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Comedications and potential drug-drug interactions with direct-acting antivirals in hepatitis C patients on hemodialysis

Hsu PY, Wei YJ, Lee JJ, Niu SW, Huang JC, Hsu CT, Jang TY, Yeh ML, Huang CI, Liang PC, Lin YH, Hsieh MY, Hsieh MH, Chen SC, Dai CY, Lin ZY, Chen SC, Huang JF, Chang JM, Hwang SJ, Chuang WL, Huang CF, Chiu YW, Yu ML

Background/Aims: Direct‐acting antivirals (DAAs) have been approved for hepatitis C virus (HCV) treatment in patients with end-stage renal disease (ESRD) on hemodialysis. Nevertheless, the complicated comedications and their potential drug-drug...
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The development of Taiwan Fracture Liaison Service network

Chang LY, Tsai KS, Peng JK, Chen CH, Lin GT, Lin CH, Tu ST, Mao IC, Gau YL, Liu HC, Niu CC, Hsieh MH, Chien JT, Hung WC, Yang RS, Wu CH, Chan DC

Osteoporosis and its associated fragility fractures are becoming a severe burden in the healthcare system globally. In the Asian-Pacific (AP) region, the rapidly increasing in aging population is the main...
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Association between Thioridazine Use and Cancer Risk in Adult Patients with Schizophrenia-A Population-Based Study

Chang CC, Hsieh MH, Wang JY, Chiu NY, Wang YH, Chiou JY, Huang HH, Ju PC

OBJECTIVE: Several cell line studies have demonstrated thioridazine’s anticancer, multidrug resistance-reversing and apoptosis-inducing properties in various tumors. We conducted this nationwide population-based study to investigate the association between thioridazine use...
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A New Perspective on the Heterogeneity of Cancer Glycolysis

Neugent ML, Goodwin J, Sankaranarayanan I, Yetkin CE, Hsieh MH, Kim JW

Tumors are dynamic metabolic systems which highly augmented metabolic fluxes and nutrient needs to support cellular proliferation and physiological function. For many years, a central hallmark of tumor metabolism has...
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