- Serum level of visfatin can reflect the severity of inflammation in patients with acute cholecystitis
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Park JW, Kim OH, Lee SC, Kim KH, Hong HE, Seo H, Choi HJ, Kim SJ
- KMID: 2503457
- Ann Surg Treat Res.
- 2020 Jul;99(1):26-36.
- doi: 10.4174/astr.2020.99.1.26
Purpose: Visfatin is a key cytokine released from the pe ripheral blood mononuclear cells (PBMCs) as well as adipose tissue, and it is involved in immune response as well as... -
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- Antioxidant action of hypoxic conditioned media from adipose-derived stem cells in the hepatic injury of expressing higher reactive oxygen species
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Hong HE, Kim OH, Kwak BJ, Choi HJ, im KH, Ahn J, Kim SJ
- KMID: 2459313
- Ann Surg Treat Res.
- 2019 Oct;97(4):159-167.
- doi: 10.4174/astr.2019.97.4.159
PURPOSE: Almost all liver diseases are known to be accompanied by increased levels of reactive oxygen species (ROS), regardless of the cause of the liver disorder. However, little is known... -
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- Potentiation of the Anticancer Effects by Combining Docetaxel with Ku-0063794 against Triple-Negative Breast Cancer Cells
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Jeon YW, Kim OH, Shin JS, Hong HE, Kim CH, Kim SJ
- KMID: 2524597
- Cancer Res Treat.
- 2022 Jan;54(1):157-173.
- doi: 10.4143/crt.2020.1063
Purpose mTORC1 and mTORC2 inhibition by Ku-0063794 could confer profound anticancer effects against cancer cells because it eliminates feedback activation of Akt. Herein, we aimed to determine anticancer effects of... -
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- 17-DMAG has the Potentiated Anticancer Effects Against Hepatocellular Carcinoma Cells by Transfection of the Gene Encoding Hepatitis B Viral X Protein
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Lee CS, Kim OH, Hong HE, Jeon SJ, Won SS, Kim SJ
- KMID: 2396567
- J Liver Cancer.
- 2017 Sep;17(2):126-135.
- doi: 10.17998/jlc.17.2.126
BACKGROUND/AIMS: Hepatitis B viral protein X (HBx) is implicated in the pathogenesis of hepatocellular carcinoma (HCC) as well as the elevation of heat shock proteins (HSPs) after hepatitis B virus... -
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- Isolation of Secretome with Enhanced Antifibrotic Properties from miR-214-Transfected Adipose-Derived Stem Cells
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Park JH, Kim OH, Kim KH, Hong HE, Seo H, Choi HJ, Ahn J, Lee TY, Kim SJ
- KMID: 2463682
- J Korean Med Sci.
- 2019 Nov;34(45):e273.
- doi: 10.3346/jkms.2019.34.e273
BACKGROUND: Secretome refers to the total set of molecules secreted or surface-shed by stem cells. The limitations of stem cell research have led numerous investigators to turn their attention to... -
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- Everolimus Plus Ku0063794 Regimen Promotes Anticancer Effects against Hepatocellular Carcinoma Cells through the Paradoxical Inhibition of Autophagy
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Lee SC, Kim KH, Kim OH, Lee SK, Hong HE, Choi BJ, Jeong W, Kim SJ
- KMID: 2417890
- Cancer Res Treat.
- 2018 Jul;50(3):1023-1038.
- doi: 10.4143/crt.2017.085
PURPOSE: Everolimus only inhibits mammalian target of rapamycin complex 1 (mTORC1), whereas Ku0063794 inhibits both mTORC1 and mTORC2. Although they have similar anticancer effects, their combination has a synergistic effect... -
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