- A polymorphism in the histone deacetylase 1 gene is associated with the response to corticosteroids in asthmatics
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Kim MH, Kim SH, Kim YK, Hong SJ, Min KU, Cho SH, Park HW
- KMID: 1780132
- Korean J Intern Med.
- 2013 Nov;28(6):708-714.
- doi: 10.3904/kjim.2013.28.6.708
BACKGROUND/AIMS: Recent investigations suggest that histone deacetylase 1 (HDAC1) and HDAC2 may be target molecules to predict therapeutic responses to corticosteroids. We evaluated the effects of variation in HDAC1 and... -
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- Response of Glucocorticoid Receptor Alpha and Histone Deacetylase 2 to Glucocorticoid Treatment Predicts the Prognosis of Sudden Sensorineural Hearing Loss
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Zhang X, Chen J, Gao Z, Qi H, Dai Y, She W
- KMID: 2462732
- Clin Exp Otorhinolaryngol.
- 2019 Nov;12(4):367-375.
- doi: 10.21053/ceo.2018.01298
OBJECTIVES: To investigate glucocorticoid receptor (GR) and histone deacetylase 2 (HDAC2) gene expression and protein levels in peripheral blood mononuclear cells (PBMCs) of patients with severe or profound sudden sensorineural... -
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- Effects of Macrolide and Corticosteroid in Neutrophilic Asthma Mouse Model
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An TJ, Rhee CK, Kim JH, Lee YR, Chon JY, Park CK, Yoon HK
- KMID: 2420594
- Tuberc Respir Dis.
- 2018 Jan;81(1):80-87.
- doi: 10.4046/trd.2017.0108
BACKGROUND: Asthma is a disease of chronic airway inflammation with heterogeneous features. Neutrophilic asthma is corticosteroid-insensitive asthma related to absence or suppression of TH2 process and increased TH1 and/or TH17... -
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