- The Overexpression of Histone Deacetylase 1 and Its Relationship with p16INK4a Gene Hypermethylation in Pulmonary Squamous Cell Carcinoma and Adenocarcinoma
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Park JH, Hong YS, Choi PJ, Kim NY, Lee KE, Roh MS
- KMID: 2073788
- Korean J Pathol.
- 2009 Apr;43(2):107-112.
BACKGROUND: DNA methylation and histone modification are dynamically linked in the epigenetic control of gene silencing and they play an important role in tumorigenesis. METHODS: To evaluate the role of histone... -
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- A polymorphism in the histone deacetylase 1 gene is associated with the response to corticosteroids in asthmatics
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Kim MH, Kim SH, Kim YK, Hong SJ, Min KU, Cho SH, Park HW
- KMID: 1780132
- Korean J Intern Med.
- 2013 Nov;28(6):708-714.
- doi: 10.3904/kjim.2013.28.6.708
BACKGROUND/AIMS: Recent investigations suggest that histone deacetylase 1 (HDAC1) and HDAC2 may be target molecules to predict therapeutic responses to corticosteroids. We evaluated the effects of variation in HDAC1 and... -
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- Expressional Difference of RHEB, HDAC1, and WEE1 Proteins in the Stromal Tumors of the Breast and Their Significance in Tumorigenesis
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Eom M, Han A, Lee MJ, Park KH
- KMID: 1439867
- Korean J Pathol.
- 2012 Aug;46(4):324-330.
- doi: 10.4132/KoreanJPathol.2012.46.4.324
BACKGROUND: Fibroadenoma (FA) and phyllodes tumor (PT) are stromal tumors of breast and are histologically similar. There are no established differences in tumorigenesis and oncogene expression among them. Ras homolog... -
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- The Modulation of Neurotrophin and Epigenetic Regulators: Implication for Astrocyte Proliferation and Neuronal Cell Apoptosis After Spinal Cord Injury
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Kim JH, Kim SH, Cho SR, Lee JY, Kim JH, Baek A, Jung HS
- KMID: 2356640
- Ann Rehabil Med.
- 2016 Aug;40(4):559-567.
- doi: 10.5535/arm.2016.40.4.559
OBJECTIVE: To investigate alterations in the expression of the main regulators of neuronal survival and death related to astrocytes and neuronal cells in the brain in a mouse model of... -
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