- Analysis of copy number abnormality (CNA) and loss of heterozygosity (LOH) in the whole genome using single nucleotide polymorphism (SNP) genotyping arrays in tongue squamous cell carcinoma
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Tsukasa K, Nobuharu Y, Takeshi O, Hiroki B, Takashi Y, Akira K, Nobuo T, Takahiko S
- KMID: 2136997
- J Korean Assoc Oral Maxillofac Surg.
- 2011 Dec;37(6):550-555.
- doi: 10.5125/jkaoms.2011.37.6.550
Chromosomal loss of heterozygosity (LOH) is a common mechanism for the inactivation of tumor suppressor genes in human epithelial cancers. LOH patterns can be generated through allelotyping using polymorphic microsatellite... -
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