- Simple Method of Preparation and Characterization of New Antifungal Active Biginelli Type Heterocyclic Compounds
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Pothiraj C, Velan AS, Joseph J, Raman N
- KMID: 2052891
- Mycobiology.
- 2008 Mar;36(1):66-69.
- doi: 10.4489/MYCO.2008.36.1.066
A simple, efficient and cost effective method is described for the synthesis of Biginelli type heterocyclic compounds of dihydropyrimidinones analogous. They were prepared from a reaction mixture consisting of substituted... -
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- Plerixafor use for peripheral blood stem cell mobilization in Korea
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Kim SJ, Yoon DH, Yang DH, Eom HS, Cho SG, Yoon SS, Lee JH, Kim WS, Suh C
- KMID: 2172902
- Blood Res.
- 2013 Jun;48(2):72-73.
- doi: 10.5045/br.2013.48.2.72
No abstract available. -
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- 68Ga-Labeled Radiopharmaceuticals for Positron Emission Tomography
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Shetty D, Lee YS, Jeong JM
- KMID: 2313117
- Nucl Med Mol Imaging.
- 2010 Dec;44(4):233-240.
68Ga is a promising emerging radionuclide for positron emission tomography (PET). It is produced using a 68Ge/68Ga-generator, and thus, would enable the cyclotron-independent distribution of PET. However, new 68Ga-labeled radiopharmaceuticals... -
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- Antifungal Activity of Securinine against Some Plant Pathogenic Fungi
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Singh AK, Pandey MB, Singh S, Singh AK, Singh UP
- KMID: 2411403
- Mycobiology.
- 2008 Jun;36(2):99-101.
The alkaloid securinine was assessed against spore germination of some plant pathogenic and saprophytic fungi (Alternaria alternata, Alternaria brassicae, Alternaria brassicicola, Curvularia lunata, Curvularia maculans, Curvularia pallenscens, Colletotrichum musae, Colletotrichum... -
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- Activation of small Rho GTPases by blebbistatin in PC12 cells
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Kim EG, Shin EY
- KMID: 1498922
- J Biomed Res.
- 2013 Jun;14(2):60-64.
Neuronal differentiation is a complex biological process accompanying cytoskeletal reorganization, including neurite outgrowth and growth cone formation. Therefore, neuronal differentiation is critically regulated by actin-related signaling proteins, such as small... -
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- Effect of phlorotannins isolated from Ecklonia cava on angiotensin I-converting enzyme (ACE) inhibitory activity
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Wijesinghe WAJP, Ko SC, Jeon YJ
- KMID: 2313504
- Nutr Res Pract.
- 2011 Apr;5(2):93-100.
Inhibition of angiotensin I-converting enzyme (ACE) activity is the most common mechanism underlying the lowering of blood pressure. In the present study, five organic extracts of a marine brown seaweed... -
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- A New Synthesis of TE2A-a Potential Bifunctional Chelator for (64)Cu
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Pandya DN, Kim JY, Kwak W, Park JC, Gawande MB, An GI, Ryu EK, Yoo J
- KMID: 1455394
- Nucl Med Mol Imaging.
- 2010 Sep;44(3):185-192.
PURPOSE: The development of a new bifunctional chelator, which holds radiometals strongly in living systems, is a prerequisite for the successful application of disease-specific biomolecules to medical diagnosis and therapy.... -
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- The Usefulness of the Computed Tomography for Diagnosing DeepVenous Thrombosis of the Lower Extremities
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Yi JH, Park SJ, Kwon EK, Oh YJ, Kang TW, Hwang JC, Kang BS, Choi SH, Cho HR
- KMID: 2096863
- J Korean Soc Vasc Surg.
- 2009 May;25(1):12-16.
PURPOSE: This study aims to access the usefulness of indirect computed tomographic venography (CTV) after performing computed tomographic pulmonary angiography (CTPA) to detect deep venous thrombosis. METHODS: Eighty six patients who... -
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- Radiolabeling of NOTA and DOTA with Positron Emitting 68Ga and Investigation of In Vitro Properties
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Jeong JM, Kim YJ, Lee YS, Lee DS, Chung JK, Lee MC
- KMID: 2313109
- Nucl Med Mol Imaging.
- 2009 Aug;43(4):330-336.
PURPOSE: We established radiolabeling conditions of NOTA and DOTA with a generator-produced PET radionuclide 68Ga and studied in vitro characteristics such as stability, serum protein binding, octanol/water distribution, and interference... -
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- Recent advances in the pharmacotherapy of psychiatric disorders
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Woo YS, Bahk WM
- KMID: 2342057
- J Korean Med Assoc.
- 2011 Oct;54(10):1061-1069.
Psychopharmacology has developed over approximately the past five decades. The remarkable proliferation of information in this area has made it difficult for clinicians to understand the characteristics of various psychotropic... -
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- Differential effects of CXCR4 antagonists on the survival and proliferation of myeloid leukemia cells in vitro
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Kim HY, Hwang JY, Oh YS, Kim SW, Lee HJ, Yun HJ, Kim S, Yang YJ, Jo DY
- KMID: 2251985
- Korean J Hematol.
- 2011 Dec;46(4):244-252.
- doi: 10.5045/kjh.2011.46.4.244
BACKGROUND: Antagonists of CXC chemokine receptor 4 (CXCR4), including AMD3100, induce peripheral mobilization of hematopoietic stem cells and have been approved for clinical use. We explored whether the CXCR4 antagonists... -
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- The CXCR4 Antagonist AMD3100 Has Dual Effects on Survival and Proliferation of Myeloma Cells In Vitro
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Kim HY, Hwang JY, Kim SW, Lee HJ, Yun HJ, Kim S, Jo DY
- KMID: 2165956
- Cancer Res Treat.
- 2010 Dec;42(4):225-234.
PURPOSE: AMD3100, an antagonist of the CXCR4 chemokine receptor is soon to be used clinically for the peripheral mobilization of hematopoietic stem cells (HSCs) in patients with multiple myeloma. AMD3100... -
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- Dynamic Contrast-Enhanced MRI Using a Macromolecular MR Contrast Agent (P792): Evaluation of Antivascular Drug Effect in a Rabbit VX2 Liver Tumor Model
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Park HS, Han JK, Lee JM, Kim YI, Woo S, Yoon JH, Choi JY, Choi BI
- KMID: 2160770
- Korean J Radiol.
- 2015 Oct;16(5):1029-1037.
- doi: 10.3348/kjr.2015.16.5.1029
OBJECTIVE: To evaluate the utility of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) using macromolecular contrast agent (P792) for assessment of vascular disrupting drug effect in rabbit VX2 liver tumor models. MATERIALS... -
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- Effect of Endogenous Bone Marrow Derived Stem Cells Induced by AMD-3100 on Expanded Ischemic Flap
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Jeong HS, Lee HK, Tark KC, Lew DH, Koh YW, Kim CH, Seo IS
- KMID: 2151419
- J Korean Med Sci.
- 2014 Nov;29(Suppl 3):S237-S248.
- doi: 10.3346/jkms.2014.29.S3.S237
The purpose of this study was to devise an expanded ischemic flap model and to investigate the role of AMD-3100 (Plerixafor, chemokine receptor 4 inhibitor) in this model by confirming... -
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- Trends in Scientific Literature on Atypical Antipsychotics in South Korea: A Bibliometric Study
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Lopez-Munoz F, Shen WW, Pae CU, Moreno R, Rubio G, Molina JD, Noriega C, Perez-Nieto MA, Huelves L, Alamo C
- KMID: 2316240
- Psychiatry Investig.
- 2013 Mar;10(1):8-16.
OBJECTIVE: We have carried out a bibliometric study on the scientific publications in relation to atypical or second-generation antipsychotic drugs (SGAs) in South Korea. METHODS: With the EMBASE and MEDLINE databases,... -
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- Early Assessment of Myocardial Contractility by Contrast-Enhanced Magnetic Resonance (ceMRI) Imaging after Revascularization in Acute Myocardial Infarction (AMI)
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Lim HE, Yong HS, Shin SH, Ahn JC, Seo HS, Oh DJ, Ro YM, Park CG
- KMID: 1109519
- Korean J Intern Med.
- 2004 Dec;19(4):213-219.
BACKGROUND: Recent studies have demonstrated that the size and shape of the hyperenhanced areas on contrast-enhanced magnetic resonance imaging (ceMRI) were nearly identical to areas of irreversible injury, as defined... -
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- MR Diagnosis of a Pulmonary Embolism: Comparison of P792 and Gd-DOTA for First-Pass Perfusion MRI and Contrast-Enhanced 3D MRA in a Rabbit Model
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Keilholz S, Bozlar U, Fujiwara N, Mata JF, Berr SS, Corot C, Hagspiel K
- KMID: 1093959
- Korean J Radiol.
- 2009 Oct;10(5):447-454.
- doi: 10.3348/kjr.2009.10.5.447
OBJECTIVE: To compare P792 (gadomelitol, a rapid clearance blood pool MR contrast agent) with gadolinium-tetraazacyclododecanetetraacetic acid (Gd-DOTA), a standard extracellular agent, for their suitability to diagnose a pulmonary embolism (PE)... -
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- Inhibitory effect of CXC chemokine receptor 4 antagonist AMD3100 on bleomycin induced murine pulmonary fibrosis
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Song JS, Kang CM, Kang HH, Yoon HK, Kim YK, Kim KH, Moon HS, Park SH
- KMID: 1078362
- Exp Mol Med.
- 2010 Jun;42(6):465-476.
- doi: 10.3858/emm.2010.42.6.048
CXC chemokine receptor 4 (CXCR4), which binds the stromal cell-derived factor-1 (SDF-1), has been shown to play a critical role in mobilizing the bone marrow (BM)-derived stem cells and inflammatory... -
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