- Short Stature Associated with Polymorphisms in Chromosome 1qh+, and 16qh+
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Kim KH, Lee SW, Kim MG, Kim DH, Kim HS
- KMID: 2321983
- J Korean Soc Pediatr Endocrinol.
- 2005 Jun;10(1):95-99.
Chromosomal polymorphism of constitutive heterochromatin regions of chromosome 1, 9, 16, and Y is a stable evolutionary feature that is thought to cause no phenotypic alterations. The presence of definite... -
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- mRNA is Synthesized Mainly at the Phase between the Euchromatin and Heterochromatin: Proposal of a Phase Theory
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Kim MS, Juhng SW
- KMID: 2275638
- Korean J Pathol.
- 2001 Apr;35(2):93-97.
BACKGROUND: Malignant cell nuclei, in general, have increased amounts of heterochromatin and decreased electron densities of euchromatin, making the chromatin pattern coarser than that of benign cell nuclei. The... -
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- The Heterochromatin-1 Phosphorylation Contributes to TPA-Induced AP-1 Expression
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Choi WJ
- KMID: 2170624
- Biomol Ther.
- 2014 Jul;22(4):308-313.
Activator protein-1 (AP-1) is an inducible transcription factor that contributes to the generation of chronic inflammation in response to oxidative and electrophilic stress. Previous studies have demonstrated that the PI3K/Akt1... -
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- A case of Roberts syndrome
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Choi Y, Chung YH, Lim IS, Kim CH, Lee DK, Kim SN, Song SY, Chi JG
- KMID: 2042044
- J Korean Pediatr Soc.
- 1993 Oct;36(10):1447-1451.
Roberts syndrome is an autosomal recessive disorder accompanied by limb defects, craniofacial abnormalities, pre-and postnatal growth retardation. Patients with Roberts syndrome have characteristic premature separation of heterochromatin of many chromosomes... -
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- Relationship between Chromatin Pattern of Tumor Cell Nuclei and Transcriptional Sites
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Juhng SW
- KMID: 2172304
- Chonnam Med J.
- 2005 Dec;41(3):253-258.
Malignant cell nuclei, in general, have increased amount of heterochromatin and decreased electron density of euchromatin, making the chromatin pattern coarser than that of benign cell nuclei. Chromatin pattern in... -
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- A Case of an Addition of Chromosome 9 Short Arm Associated with Multiple Congenital Anomalies
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Chang SG, Yu JE, Park MS, Lim YJ, Yoon SH, Hong J
- KMID: 1477475
- J Korean Soc Neonatol.
- 2008 Nov;15(2):200-206.
Human chromosome 9 is characterized by a high degree of morphologic heteromorphisms, including variation in the size of the heterochromatin. We present a case of a de novo short arm... -
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- Prenatal diagnosis of interchromosomal insertion of Y chromosome heterochromatin in a family
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Lee BY, Park JY, Lee YW, Oh AR, Lee SY, Park SY, Ryu HM, Lee SW
- KMID: 2401807
- J Genet Med.
- 2017 Dec;14(2):62-66.
- doi: 10.5734/JGM.2017.14.2.62
Interchromosomal insertion of Y chromosome heterochromatin in an autosome was identified in a fetus and a family. A fetal karyotype was analyzed as 46,XX,dup(7)(?q22q21.1) in a referred amniocentesis at 16... -
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- Chromatin Pattern-Dependent mRNA Synthesis in HeLa Cells and HeLa Tumors
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Lee JH, Kang MW, Choi C, Juhng SW
- KMID: 2172398
- Chonnam Med J.
- 2001 Dec;37(4):351-356.
Malignant cell nuclei, in general, have increased amount of heterochromatin and decreased electron density of euchromatin, making the chromatin pattern coarser than that of benign cell nuclei. Chromatin pattern in... -
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- A Case of the Roberts SC Syndrome at the 17 Weeks of Gestational Age
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Kim KH, Lee KH, Park MC, Sohn JH, Lee YW
- KMID: 2269626
- Korean J Obstet Gynecol.
- 1999 May;42(5):1138-1141.
Roberts SC syndrome was initially described by Roberts in 1919 and more recently by Appelt et al. It`s transmitted as an autosomal recessive condition. Approximately 80 percent of affected... -
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- Detection of a Familial Y/l5 Translocation by FISH, G-Banding, C-Banding, and Ag-NOR Stain
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Lee KM, Kim KH, Han JY, Je GH, Shaffer LG
- KMID: 2146218
- Korean J Clin Pathol.
- 1997 Dec;17(6):1176-1181.
Prenatal chromosome analysis of amniotic cells at 18 weeks of gestation showed a male fetus to carry a large 15p+ derivative chromosome inherited from his mother. Extra genetic material on... -
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- Interplay between Epigenetics and Genetics in Cancer
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Choi JD, Lee JS
- KMID: 2166498
- Genomics Inform.
- 2013 Dec;11(4):164-173.
- doi: 10.5808/GI.2013.11.4.164
Genomic instability, which occurs through both genetic mechanisms (underlying inheritable phenotypic variations caused by DNA sequence-dependent alterations, such as mutation, deletion, insertion, inversion, translocation, and chromosomal aneuploidy) and epigenomic aberrations... -
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- The Effect of Mitomycin C(MMC) on Sinus Mucosal Openings in Rabbits
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Kim BK, Chung WS
- KMID: 2206015
- J Korean Ophthalmol Soc.
- 2001 Jul;42(7):1016-1029.
PURPOSE: This experimental study investigates the effect of mitomycin C(MMC) on the healing of sinus mucosal opening. METHODS: One hundred and twenty rabbits were used and divided into 8 groups... -
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- Molecular and Cytogenetic Findings in 46,XX Males
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Choi SK
- KMID: 1538078
- J Genet Med.
- 1998 Mar;2(1):11-16.
This paper reports 3 cases with 46,XX sex reversed male. Three 46,XX hypogonadal subjects showed complete sex reversal and had normal phallus and azoospermia. We studied them under clinical, cytogenetic... -
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- Effect of Paclitaxel on the beta-actin, Fibronectin, Laminin and Fine Structure in HeLa and L929 Cells
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Kim JY, Liu Y, Sung HK, Park JH, Song IH, Sung EG, Lee Y
- KMID: 2030734
- Korean J Anat.
- 2001 Feb;34(1):1-11.
The aim of this investigation was to elucidate the changes in the cytoplasmic distribution of beta-actin, fibronectin, and laminin through mainly the morphological changes occurring in HeLa and L929 cancer... -
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- A study of Digital Image Analysis of Chromatin Texture for Discrimination of Thyroid Neoplastic Cells
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Juhng SW, Lee JH, Bum EK, Kim CW
- KMID: 2226488
- Korean J Cytopathol.
- 1996 Jun;7(1):23-30.
Chromatin texture, which partly reflects nuclear organization, is evolving as an important parameter indicating cell activation or transformation. In this study, chromatin pattern was evaluated by image analysis of the... -
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- Interactome Analysis Reveals that Heterochromatin Protein 1gamma (HP1gamma) Is Associated with the DNA Damage Response Pathway
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Kim H, Choi JD, Kim BG, Kang HC, Lee JS
- KMID: 2152291
- Cancer Res Treat.
- 2016 Jan;48(1):322-333.
- doi: 10.4143/crt.2014.294
PURPOSE: Heterochromatin protein 1gamma (HP1gamma) interacts with chromosomes by binding to lysine 9-methylated histone H3 or DNA/RNA. HP1gamma is involved in various biological processes. The purpose of this study is... -
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- Effects of Melatonin on Fine Structures and Extracellular Matrix Proteins of Cancer Cell Lines
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Sung EK, Jeong HG, Song IH, Kim JY, Lee Y
- KMID: 2224581
- Korean J Anat.
- 1999 Apr;32(2):199-210.
Melatonin could be used as an anticancer agent to suppress the proliferation of tumor cells and induce the differentiation of cancer cells. HeLa, HepG2, A549, L929, and NIH/3T3 cell lines... -
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- Targeted Downregulation of kdm4a Ameliorates Tau-engendered Defects in Drosophila melanogaster
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Park SY, Seo J, Chun YS
- KMID: 2455488
- J Korean Med Sci.
- 2019 Aug;34(33):e225.
- doi: 10.3346/jkms.2019.34.e225
BACKGROUND: Tauopathies, a class of neurodegenerative diseases that includes Alzheimer's disease (AD), are characterized by the deposition of neurofibrillary tangles composed of hyperphosphorylated tau protein in the human brain. As... -
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- Molecular Analysis of the Y Chromosome in a 46,XY Female Phenotype
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Kim JW, Kim TJ, Park SY, Nam SA, Jun JY
- KMID: 1536936
- J Genet Med.
- 1999 Dec;3(1):5-10.
This is a case report of 46,XY female phenotype (46,XY karyotype, no pubic hair, blind vagina and absence of uterus)in an 18-year-old patient. To confirm whether a Y chromosome has... -
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- Protective Effect of Cholesteryl Hemisuccinate on Fumonisin B1-nduced Apoptosis of Hepatocytes in the Rat Liver
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Moon WS, Park CK, Kang MJ, Lee DG, Choi HY
- KMID: 2241314
- Korean J Hepatol.
- 1999 Sep;5(3):227-239.
BACKGROUND/AIMS: This study was aimed to examine if FB1 induced-hepatotoxicity involves apoptosis, and cholesteryl hemisuccinate (CS) pre-treatment would selectively interfere with FB1 induced-apoptosis of hepatocytes. METHODS: Sprague-Dawley rats were intravenousely... -
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