- Clinical Implications of Genetic Testing for Hereditary Breast and Ovarian Cancer Syndrome in the Era of Genomic Medicine: Clinician's Perspectives
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Park HS, Park JS, Nam EJ, Lee ST, Han JW, Kim TI
- KMID: 2360680
- J Breast Dis.
- 2016 Jun;4(1):1-9.
- doi: 10.14449/jbd.2016.4.1.1
Hereditary breast and ovarian cancer syndrome accounts for approximately 5% to 10% of breast or ovarian cancers, with which the high-penetrant BRCA1/2 genes have been associated. With the recent development... -
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- A Study on Genetic Knowledge and Anxiety in Patients with Breast Cancer
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Seo H, Yi M
- KMID: 2392514
- Asian Oncol Nurs.
- 2017 Sep;17(3):151-157.
- doi: 10.5388/aon.2017.17.3.151
PURPOSE: The purpose of the study was to understand the levels of knowledge about hereditary breast cancer and anxiety among patients with breast cancer and to identify the relationship between... -
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- Knowledge and Anxiety Related to Hereditary Ovarian Cancer in Serous Ovarian Cancer Patients
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Lee SH, Lee H, Lim MC, Kim S
- KMID: 2465979
- Korean J Women Health Nurs.
- 2019 Dec;25(4):365-378.
- doi: 10.4069/kjwhn.2019.25.4.365
PURPOSE: The awareness of hereditary breast and ovarian cancer (HBOC) and BRCA testing is increasing in Korea. Compared to the sizable research on HBOC knowledge among breast cancer women, studies... -
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- Clinical Validity of Next-Generation Sequencing Multi-Gene Panel Testing for Detecting Pathogenic Variants in Patients With Hereditary Breast-Ovarian Cancer Syndrome
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Yoo J, Lee GD, Kim JH, Lee SN, Chae H, Han E, Kim Y, Kim M
- KMID: 2460912
- Ann Lab Med.
- 2020 Mar;40(2):148-154.
- doi: 10.3343/alm.2020.40.2.148
BACKGROUND: Hereditary breast and ovarian cancer syndrome (HBOC) is caused by pathogenic variants in BRCA and other cancer-related genes. We analyzed variants in BRCA gene and other cancer-related genes in... -
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- Contralateral Breast Cancer and Ipsilateral Breast Tumor Recurrence in BRCA1/2 Carriers and Non-Carriers at High-Risk of Hereditary Breast Cancer
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Yoon KH, Chae S, Kang E, Shin HC, Kim JH, Kim IA, Park SY, Kim SW, Kim EK
- KMID: 2470895
- J Breast Cancer.
- 2019 Dec;22(4):587-598.
- doi: 10.4048/jbc.2019.22.e47
PURPOSE: We evaluated the risk of contralateral breast cancer (CBC) and ipsilateral breast tumor recurrence (IBTR) and investigated the predictive factors for CBC and IBTR in breast cancer patients with... -
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- Analysis of BRIP1 Variants among Korean Patients with BRCA1/2 Mutation-Negative High-Risk Breast Cancer
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Kim H, Cho DY, Choi DH, Jung GH, Shin I, Park W, Huh SJ, Nam SJ, Lee JE, Gil WH, Kim SW
- KMID: 2344068
- Cancer Res Treat.
- 2016 Jul;48(3):955-961.
- doi: 10.4143/crt.2015.191
PURPOSE: The aim of the current study is to assess the spectrum of genetic variation in the BRIP1 gene among Korean high-risk breast cancer patients who tested negative for the... -
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- The influence of BRCA variants of unknown significance on cancer risk management decision-making
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Chern JY, Lee SS, Frey MK, Lee J, Blank SV
- KMID: 2450239
- J Gynecol Oncol.
- 2019 Jul;30(4):e60.
- doi: 10.3802/jgo.2019.30.e60
OBJECTIVE: To compare gynecological cancer risk management between women with BRCA variants of unknown significance (VUS) to women with negative genetic testing METHODS: Ninety-nine patients whose BRCA genetic testing yielded VUS... -
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- Comparison of Targeted Next-Generation and Sanger Sequencing for the BRCA1 and BRCA2 Mutation Screening
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Park J, Jang W, Chae H, Kim Y, Chi HY, Kim M
- KMID: 2373527
- Ann Lab Med.
- 2016 Mar;36(2):197-201.
- doi: 10.3343/alm.2016.36.2.197
No abstract available. -
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