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Adenoviral mediated hepatocyte growth factor gene attenuates hyperglycemia and beta cell destruction in overt diabetic mice

Park MK, Kim DK, Lee HJ

  • KMID: 1119330
  • Exp Mol Med.
  • 2003 Dec;35(6):494-500.
Hepatocyte growth factor (HGF) is a potent mitogen and promoter of proliferation of insulin producing beta cells of pancreatic islets. To study the role of HGF, an adenoviral vector carrying...
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Immunomodulatory effects of human amniotic membrane-derived mesenchymal stem cells

Kang JW, Koo HC, Hwang SY, Kang SK, Ra JC, Lee MH, Park YH

Human amniotic membrane-derived mesenchymal stem cells (hAM-MSCs) are capable of differentiating into several lineages and possess immunomodulatory properties. In this study, we investigated the soluble factor-mediated immunomodulatory effects of hAM-MSCs....
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Islet Transplantation and Regeneration for Treatment of Diabetes

Yamada Y

Islet transplantation has the potential to restore normoglycemia and prevent the development of diabetic complications such as retinopathy, nephropathy and neuropathy, and could therefore ve a valuable treatment for diabetic...
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