- Mutations of hepatitis C virus 1b NS5A 2209-2248 amino acid sequence is not a edictive factor for response to interferon-alpha therapy and development of patocellular carcinoma
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Bae SH, Park YM, Yoo DG, Choi JY, Byun BH, Yang JM, Lee CD, Cha SB, Park DH, KiM BS
- KMID: 1731234
- J Korean Med Sci.
- 2000 Feb;15(1):53-58.
- doi: 10.3346/jkms.2000.15.1.53
Genetic changes between codons 2209 and 2248 of NS5A of genotype 1b hepatitis C virus (HCV-1b) have been reported to be associated with the sensitivity to interferon-alpha (IFN-alpha). The present... -
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- Expression of Transforming Growth Factor beta-1 in Chronic Hepatitis and Hepatocellular Carcinoma Associated with Hepatitis C Virus Infection
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Kim HG, Chung YH, Song BC, Kim JA, Yang SH, Lee YS, Suh DJ
- KMID: 759514
- Korean J Intern Med.
- 2000 Dec;15(3):165-170.
BACKGROUND: Transforming growth factor beta-1 (TGF beta 1) has been suggested to play a role in the development, growth or progression of hepatocellular carcinoma (HCC). Genotype and serum titer of... -
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- The prediction of interferon-alpha therapeutic effect by sequence variation of the HCV hypervariable region 1
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Yeh BI, Kim HW, Kim HS, Lee JY, Lee KH, Lee KM, Kim JS, Han KH
- KMID: 711674
- Yonsei Med J.
- 1999 Oct;40(5):430-438.
- doi: 10.3349/ymj.1999.40.5.430
Interferon-alpha (IFN-alpha) has been used to treat hepatitis C virus (HCV)-induced hepatitis, but it has been effective in only about half of the treated patients, with recurrence appearing in the... -
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