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Differences in the patterns and outcomes of enhanced viral replication between hepatitis C virus and hepatitis B virus in patients with hepatocellular carcinoma during transarterial chemolipiodolization

Sung PS, Bae SH, Jang JW, Song DS, Kim HY, Yoo SH, Park CH, Kwon JH, Song MJ, You CR, Choi JY, Yoon SK

BACKGROUND/AIMS: Enhanced replication of hepatitis C virus (HCV) is well described in the setting of moderate to severe immunosuppression. The aims of this retrospective study were to determine the incidence...
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Changes of guidelines diagnosing hepatocellular carcinoma during the last ten-year period

Song DS, Bae SH

Hepatocellular carcinoma (HCC) is the third most common cause of cancer deaths in the world. There have been many advances in the diagnosis of HCC during the last ten years,...
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Regression of esophageal varices and splenomegaly in two patients with hepatitis-C-related liver cirrhosis after interferon and ribavirin combination therapy

Lee SJ, Cho YK, Na SY, Choi EK, Boo SJ, Jeong SU, Song HJ, Kim HU, Kim BS, Song BC

Some recent studies have found regression of liver cirrhosis after antiviral therapy in patients with hepatitis C virus (HCV)-related liver cirrhosis, but there have been no reports of complete regression...
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Renewed 2015 Clinical Practice Guidelines for Management of Hepatitis C by Korean Association for the Study of the Liver; What Has Been Changed? - Treatment of Patients with Decompensated Cirrhosis

Gwak GY

HCV-related decompensated liver cirrhosis is a life-threatening illness with an average 5-year survival rate of 50%. Because these patients have higher risk of morbidity and mortality including development of hepatocellular...
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The significance of anti-HBc and occult hepatitis B virus infection in the occurrence of hepatocellular carcinoma in patients with HBsAg and anti-HCV negative alcoholic cirrhosis

Kim MJ, Kwon OS, Chung NS, Lee SY, Jung HS, Park DK, Ku YS, Kim YK, Kim YS, Kim JH

BACKGROUND/AIMS: Alcohol and the hepatitis B virus (HBV) exert synergistic effects in hepatocelluar carcinogenesis. We aimed to elucidate the clinical significance of the antibody to hepatitis B core antigen...
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Hepatocellular Carcinoma in the Elderly: Clinical Characteristics, Treatment, Survival Analysis in Korean Patients Older than 70 Years

Kim YJ, Jang BK, Kim ES, Chung WJ, Park KS, Cho KB, Hwang JS

The prevalence of hepatocellular carcinoma (HCC) has increased in recent years. However, HCC remains poorly characterized in elderly patients, and comprehensive data are limited. This study aimed to investigate the...
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Prevalence and Clinical Significance of Diabetes Mellitus in Patients with Liver Cirrhosis

Kwon SY

  • KMID: 863156
  • Korean J Hepatol.
  • 2003 Sep;9(3):205-211.
BACKGROUND/AIMS: Impaired glucose tolerance and overt diabetes mellitus (DM) frequently occurs in patients with chronic liver disease. Hyperinsulinaemia and peripheral insulin resistance contribute to the development of DM in these...
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Recurrence and Management of Hepatitis C after Liver Transplantation

Oh KB, Lee SG, Lee YJ, Park KM, Hwang S, Kim KH, Ahn CS, Moon DB, Chu CW, Yang HS, Ha TY, Cho SH

  • KMID: 863153
  • Korean J Hepatol.
  • 2003 Sep;9(3):180-187.
BACKGROUND/AIMS: End-stage liver disease caused by viral hepatitis C has been increasing recently in Korea. In this study, we investigated the clinical progress, recurrence, and management of hepatitis C patients...
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Hepatitis C virus-induced hepatocellular carcinoma

Goossens N, Hoshida Y

Hepatitis C virus (HCV) is a leading etiology of hepatocellular carcinoma (HCC). The interaction of HCV with its human host is complex and multilayered; stemming in part from the fact...
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Is the Prevalence of Cryptogenic Hepatocellular Carcinoma Increasing in Korea?

Oh KC, Park SH, Park JC, Jin DK, Park CS, Kim KO, Jang HJ, Lee JY, Park CH, Han TH, Yoo KS, Kim JH, Kim DJ, Lee MS, Park CK

  • KMID: 772716
  • Korean J Gastroenterol.
  • 2005 Jan;45(1):45-51.
BACKGROUND/AIMS: Nonalcoholic fatty liver disease (NAFLD) has been characterized by a wide spectrum of liver damages that span from steatosis to cryptogenic liver cirrhosis and even to hepatocellular carcinoma...
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Serum bilirubin levels are inversely associated with nonalcoholic fatty liver disease

Kwak MS, Kim D, Chung GE, Kang SJ, Park MJ, Kim YJ, Yoon JH, Lee HS

BACKGROUND/AIMS: Serum bilirubin exerts antioxidant and cytoprotective effects. In addition, elevated serum bilirubin levels are associated with a decreased risk of metabolic and cardiovascular diseases. However, few studies have evaluated...
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Usefulness of Non-invasive Markers for Predicting Significant Fibrosis in Patients with Chronic Liver Disease

Lee HH, Seo YS, Um SH, Won NH, Yoo H, Jung ES, Kwon YD, Park S, Keum B, Kim YS, Yim HJ, Jeen YT, Chun HJ, Kim CD, Ryu HS

The purpose of this prospective study was to verify and compare the strengths of various blood markers and fibrosis models in predicting significant liver fibrosis. One hundred fifty-eight patients with...
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The relationship between hepatitis B virus infection and the incidence of pancreatic cancer: a retrospective case-control study

Hong SG, Kim JH, Lee YS, Yoon E, Lee HJ, Hwang JK, Jung ES, Joo MK, Jung YK, Yeon JE, Park JJ, Kim JS, Bak YT, Byun KS

BACKGROUND/AIMS: An association between past history of hepatitis B virus (HBV) infection and pancreatic cancer (PC) has recently been reported. We investigated whether HBV and hepatitis C virus (HCV) infections...
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Parvovirus B19-induced Pure Red Cell Aplasia in a Liver Transplant Recipient

Lee EY, Cho Y, Lee SG, Song J

Parvovirus B19 infection is known to cause chronic anemia in immunocompromised hosts, including organ transplant recipients. We report the first case of liver transplant recipient with parvovirus B19-induced pure red...
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The usefulness of non-invasive liver stiffness measurements in predicting clinically significant portal hypertension in cirrhotic patients: Korean data

Hong WK, Kim MY, Baik SK, Shin SY, Kim JM, Kang YS, Lim YL, Kim YJ, Cho YZ, Hwang HW, Lee JH, Chae MH, Kim HA, Kang HW, Kwon SO

BACKGROUND/AIMS: Liver stiffness measurement (LSM) has been proposed as a non-invasive method for estimating the severity of fibrosis and the complications of cirrhosis. Measurement of the hepatic venous pressure gradient...
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Long-term outcome of preoperative transarterial chemoembolization and hepatic resection in patients with hepatocellular carcinoma

Kang JY, Choi MS, Kim SJ, Kil JS, Lee JH, Koh KC, Paik SW, Yoo BC

BACKGROUND/AIMS: Transarterial chemoembolization (TACE) improves the survival of patients with unresectable hepatocellular carcinoma (HCC) and has been recommended as a first-line therapy for nonsurgical patients with large or multifocal HCC....
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Clinical significance and predictive factors of early massive recurrence after radiofrequency ablation in patients with a single small hepatocellular carcinoma

Cho JY, Choi MS, Lee GS, Sohn W, Ahn J, Sinn DH, Gwak GY, Paik YH, Lee JH, Koh KC, Paik SW

BACKGROUND/AIMS: Radiofrequency ablation (RFA) is one of the most frequently applied curative treatments in patients with a single small hepatocellular carcinoma (HCC). However, the clinical significance of and risk factors...
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