- Inhibition of hepatitis B virus replication by RNA interference
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Park YG
- KMID: 1776809
- Korean J Hepatol.
- 2009 Mar;15(1):1-6.
- doi: 10.3350/kjhep.2009.15.1.1
No abstract available. -
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- Efficacy of Entecavir Treatment in Hepatitis B Virus-related Decompensated Cirrhosis
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Kim YS
- KMID: 1245203
- Korean J Gastroenterol.
- 2012 Mar;59(3):203-204.
- doi: 10.4166/kjg.2012.59.3.203
No abstract available. -
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- Emergence of vaccine-induced escape mutant of hepatitis b virus with multiple surface gene mutations in a korean child
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Lee KM, Kim YS, Ko YY, Yoo BM, Lee KJ, Kim JH, Hahm KB, Cho SW
- KMID: 1129912
- J Korean Med Sci.
- 2001 Jun;16(3):359-362.
- doi: 10.3346/jkms.2001.16.3.359
The S protein of hepatitis B virus is the principal component of virus envelope and the primary target of anti-HBs response. Mutants or variants that escape neutralization by anti-HBs have... -
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- Therapeutic Strategy for YMDD Mutants of Hepatitis B Virus
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Ryu SH, Chung YH
- KMID: 760526
- Korean J Hepatol.
- 2004 Mar;10(1):1-10.
No abstract available. -
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- New Insight for HBV DNA and HBsAg Quantitation during Antiviral Therapy in Patients with Chronic Hepatitis B
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Cho YK, Song BC
- KMID: 1128352
- Korean J Gastroenterol.
- 2011 Mar;57(3):144-149.
- doi: 10.4166/kjg.2011.57.3.144
Over the past decade, advances in the antiviral therapy in patients with chronic hepatitis B have enabled the sustained suppression of hepatitis B viral replication and the prevention of progressive... -
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- Relationship Between Core Gene Mutations of Hepatitis B Virus and Response to Alpha Interferon Therapy in Chronic Hepatitis B
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Yoo BC, Kim HJ, Do JH, Park SM
- KMID: 863113
- Korean J Hepatol.
- 2002 Dec;8(4):381-388.
BACKGROUND/AIMS: Treatment of chronic hepatitis B with interferon results in a sustained loss of hepatitis B virus DNA and hepatitis B e antigen (HBeAg) and remission of liver disease... -
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- Overlapping Gene Mutations of Hepatitis B Virus in a Chronic Hepatitis B Patient with Hepatitis B Surface Antigen Loss during Lamivudine Therapy
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Lee SY, Choi MS, Lee D, Lee JH, Koh KC, Paik SW, Yoo BC
- KMID: 1778502
- J Korean Med Sci.
- 2005 Jun;20(3):433-437.
- doi: 10.3346/jkms.2005.20.3.433
Disappearance of hepatitis B surface antigens (HBsAg) in chronic hepatitis B usually indicates clearance of hepatitis B virus (HBV) infection. However, false HBsAg negativity with mutations in pre-S2 and 'a'... -
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- Gene Expression Profile in Response to Hepatitis B Virus X Gene by Using an Adenoviral Vector
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Joo HY, Han KH, Ryu WS
- KMID: 863112
- Korean J Hepatol.
- 2002 Dec;8(4):371-380.
BACKGROUND/AIMS: Hepatitis B virus (HBV) is the etiological factor for hepatocellular carcinoma (HCC). Numerous evidence has indicated a link between chronic infection with HBV and the development of HCC.... -
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- Mutations in the pre-core region of hepatitis B virus DNA in patients with chronic liver diseases
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Kim WH, Kim KH, Chung JP, Kang JK, Park IS
- KMID: 1729604
- Yonsei Med J.
- 1993 Jun;34(2):158-165.
- doi: 10.3349/ymj.1993.34.2.158
To investigate the prevalence of point mutation in the pre-core (pre-C) region of hepatitis B virus (HBV) DNA, we performed dot blot hybridization and sequencing of enzymatically amplified HBV DNA... -
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- Identification of integrated hepatitis B virus DNA sequences in human hepatocellular carcinomas in Korea
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Lee HS, Kim ST, Kim CY
- KMID: 1421492
- J Korean Med Sci.
- 1990 Sep;5(3):145-148.
- doi: 10.3346/jkms.1990.5.3.145
The rate of HBV DNA integration into the genome of hepatocellular carcinoma (HCC) cells varies greatly among HCC tissues from different geographical districts. Because of the potential etiological significance of... -
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- Inhibition of in vitro hepatitis B virus replication by lentivirus-mediated short-hairpin RNA against HBx
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Kim JW, Lee SH, Park YS, Jeong SH, Kim N, Lee DH
- KMID: 1776811
- Korean J Hepatol.
- 2009 Mar;15(1):15-24.
- doi: 10.3350/kjhep.2009.15.1.15
BACKGROUNDS/AIMS: Hepatitis B virus (HBV) replicates via RNA intermediates, which could serve as targets for RNA interference (RNAi). Vector-mediated short-hairpin RNA (shRNA) can induce sustained RNAi in comparison to small... -
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- The Prevalence and Clinical Significance of Precore and Core Promoter Mutations in Korean Patients with hronic Hepatitis B Virus Infection
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Kim HJ, Yoo BC
- KMID: 1123164
- Korean J Hepatol.
- 2002 Jun;8(2):149-156.
BACKGROUND/AIMS: Precore and core promoter mutations of hepatitis B virus (HBV) have been reported in Korea but their prevalence and clinical significance have not been determined. The aims of this... -
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- Clinical significance of occult hepatitis B virus infection in chronic hepatitis C patients
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Jang JY, Jeong SW, Cheon SR, Lee SH, Kim SG, Cheon YK, Kim YS, Cho YD, Kim HS, Jin SY, Kim YS, Kim BS
- KMID: 1025200
- Korean J Hepatol.
- 2011 Sep;17(3):206-212.
- doi: 10.3350/kjhep.2011.17.3.206
BACKGROUND/AIMS: We investigated the frequency of occult hepatitis B virus (HBV) infection in anti-hepatitis C virus (HCV)-positive individuals and the effects of occult HBV infection on the severity of liver... -
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- Precore and Core Promoter Mutations of the Hepatitis B Virus Gene in Chronic Genotype C -Infected Children
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Kang HS, Kang KS, Song BC
- KMID: 1777886
- J Korean Med Sci.
- 2011 Apr;26(4):546-550.
- doi: 10.3346/jkms.2011.26.4.546
The precore (G1896A) and core promoter (A1762T, G1764A) mutations of the hepatitis B virus gene are known to be associated with changes in immunologic phase or the progression to complicated... -
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- Analysis of Clinical Characteristics and S Gene Mutation of Hepatitis B Virus (HBV) in Patients with Hepatitis B Surface Antigen RIA Negative and HBV DNA Positive
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Sohn YH, Oh HB, Ko SY, Lim YS, Kwon OJ
- KMID: 1096974
- Korean J Lab Med.
- 2009 Jun;29(3):224-230.
- doi: 10.3343/kjlm.2009.29.3.224
BACKGROUND: We investigated hepatitis B virus (HBV) infection cases, who were HBsAg negative by radioimmunoassay (RIA) and HBV DNA positive for their clinical characteristics, the S gene mutation of hepatitis... -
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- Natural YMDD Motif Mutations of HBV Polymerase in the Chronic Hepatitis B Virus Infected Patients
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Shin YM, Cho M, Heo J, Kim GH, Kang DH, Song GA, Yang US, Kim CM, Park HK, Jang HJ
- KMID: 1011389
- Korean J Hepatol.
- 2003 Mar;9(1):1-9.
BACKGROUND/AIMS: Lamivudine, a nucleoside analogue has been widely used as an effective antiviral agent for the treatment of patients with chronic hepatitis B infection. However, the YMDD motif mutation... -
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- Distribution of Hepatitis B Virus Genotypes according to the Clinical Outcomes in Patients with Chronic Hepatitis B Virus Infection in Jeju Island
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Kim BJ, Song BC
- KMID: 1066040
- Korean J Gastroenterol.
- 2003 Dec;42(6):496-501.
BACKGROUND/AIMS: The genotype of hepatitis B virus (HBV) has been suggested to correlate with the clinical outcome of HBV infection. We analyzed the distribution of HBV genotypes according to... -
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- Comparative Analysis of Liver Injury-Associated Cytokines in Acute Hepatitis A and B
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Shin SY, Jeong SH, Sung PS, Lee J, Kim HJ, Lee HW, Shin EC
- KMID: 2374085
- Yonsei Med J.
- 2016 May;57(3):652-657.
- doi: 10.3349/ymj.2016.57.3.652
PURPOSE: Acute hepatitis A (AHA) and acute hepatitis B (AHB) are caused by an acute infection of the hepatitis A virus and the hepatitis B virus, respectively. In both AHA... -
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- Detection of YMDD Motif Mutants by Oligonucleotide Chips in Lamivudine-Untreated Patients with Chronic Hepatitis B Virus Infection
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Heo J, Cho M, Kim HH, Shin YM, Jang HJ, Park HK, Kim CM, Kim GH, Kang DH, Song GA, Yang US
- KMID: 2157683
- J Korean Med Sci.
- 2004 Aug;19(4):541-546.
- doi: 10.3346/jkms.2004.19.4.541
Lamivudine, a nucleoside analogue, has been used widely as an effective antiviral agent for the treatment of patients with chronic hepatitis B virus (HBV) infection. However, the YMDD motif mutation... -
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- Hepatitis B Virus Genotype C Prevails Among Chronic Carriers of the Virus in Korea
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Bae SH, Yoon SK, Jang JW, Kim CW, Nam SW, Choi JY, Kim BS, Park YM, Suzuki S, Sugauchi F, Mizokami M
- KMID: 1781765
- J Korean Med Sci.
- 2005 Oct;20(5):816-820.
- doi: 10.3346/jkms.2005.20.5.816
Hepatitis B virus (HBV) is one of the major causative agents of chronic liver diseases in Korea. HBV has been classified into 8 genotypes by a divergence of >8% in... -
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