- Correlation of HBV DNA Level and Viral Breakthrough During Lamivudine Therapy for Chronic Hepatitis B
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Park HS, Lee DH, Heo J, Kim GH, Kang DH, Song GA, Cho M
- KMID: 760644
- Korean J Hepatol.
- 2006 Jun;12(2):173-183.
BACKGROUND/AIMS: Lamivudine is an effective therapy in chronic hepatitis B patients, but the emergence of resistant hepatitis B virus (HBV) mutants is a major concern. This study was performed... -
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- Clinical Outcome in Cases of Viral Breakthrough During Lamivudine Therapy in Chronic Hepatitis B Patients
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Ahn SH, Chang YJ, Oh SN, Choi DW, Baek SJ, Jeong WS, Choi CW, Kim KO, Yim HJ, Jo NY, Bak JJ, Kim JS, Bak YT, Lee MS, Yeon JE, Byun KS, Lee CH
- KMID: 863114
- Korean J Hepatol.
- 2002 Dec;8(4):389-396.
BACKGROUND/AIMS: Long-term lamivudine therapy can induce the emergence of lamivudine resistant hepatitis B virus (HBV) mutants. Clinically emergence of the mutant is expressed by the reappearance of disappeared HBV... -
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- Predictive Factors and Clinical Outcome of Viral Breakthrough during Lamivudine Treatment for Chronic Hepatitis B Infection
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Park NH, Shin JW, Park JH, Bang SJ, Kim DH, Joo KR, Kim DH
- KMID: 1085302
- Korean J Hepatol.
- 2003 Dec;9(4):293-303.
BACKGROUND/AIMS: Long-term treatment with lamivudine causes breakthrough, but the clinical course after lamivudine breakthrough is not well known. The aims of this study were to evaluate the clinical course... -
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- Elecsys Hepatitis B Surface Antigen Quantitative Assay: Performance Evaluation and Correlation with Hepatitis B Virus DNA during 96 Weeks of Follow-up in Chronic Hepatitis B Patients
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Lee HJ, Kim SY, Lee SM, Heo J, Kim HH, Chang CL, Lee EY, Son HC
- KMID: 2434483
- Ann Lab Med.
- 2012 Nov;32(6):420-425.
BACKGROUND: Treatment for chronic hepatitis B aims to suppress virus replication and virus sequestration in hepatocytes. Covalently closed circular (ccc) DNA is the template for transcription of viral genes and... -
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- HBV DNA Loss within 24 Weeks Predicts Late Viral Breakthrough in Chronic Hepatitis B
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Jeon SR, Jang JY, Jeong SW, Park SH, Lee SH, Kim SG, Cheon YK, Kim YS, Cho YD, Moon JH, Kim HS, Lee JS, Kim BS
- KMID: 1792811
- Korean J Gastroenterol.
- 2011 Jul;58(1):25-30.
- doi: 10.4166/kjg.2011.58.1.25
BACKGROUND/AIMS: Sustained HBV DNA reduction is necessary for biochemical remission, histological improvement, and prevention of complications. We analyzed the time taken from HBV DNA loss to viral breakthrough after antiviral... -
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