- The effect of growth factor receptor HER2 on the estrogen receptor transcriptional activities and its implications
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Heo MK, Park SO, Jung SY, Kim SI, Park BW
- KMID: 2174951
- J Breast Cancer.
- 2005 Sep;8(3):105-112.
- doi: 10.4048/jbc.2005.8.3.105
PURPOSE: Until recently, breast cancer carcinogenesis has not been fully understood, but the roles of estrogen receptors(ERs) and growth factor receptors(like HER2) were known to be important. Growth factors have... -
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- Expression of Estrogen Receptor-beta mRNA in Various Mammary Tissues
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Park BW, Kim KS, Heo MK, Hong SW, Kim SI, Lee KS
- KMID: 2006610
- J Korean Breast Cancer Soc.
- 2003 Jun;6(2):75-80.
- doi: 10.4048/jkbcs.2003.6.2.75
PURPOSE: Estrogen signal transduction plays very important roles in both normal mammary development and neoplastic progression. Since the discovery of estrogen receptor-beta (ER-beta) there have been many controversial reports on... -
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- Anti-HER2/neu Peptide Producing Vector System for Biologic Therapy - Is It Possible to Mass-produce the Peptide?
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Park BW, Kim KS, Heo MK, Lee KS, Kim EK, Kim KS
- KMID: 1719070
- Yonsei Med J.
- 2003 Feb;44(1):58-64.
- doi: 10.3349/ymj.2003.44.1.58
A humanized monoclonal antibody against HER2 has been using in a clinical setting and has been shown to possess therapeutic properties. A mimetic peptide against HER2 was also reported to... -
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- Mitogen-activated Protein Kinases Activities and c-erbB-2 Expression in Breast Cancer Carcinogenesis and Progression
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Park BW, Heo MK, Kim KS, Ko SS, Kim SI, Lee KS
- KMID: 2209585
- J Korean Surg Soc.
- 2003 Jan;64(1):6-13.
PURPOSE: Increased level mitogen-activated protein kinase (MAPK) and activation of MAPK have been reported in human breast cancers, especially in breast cancers with HER2/neu overexpression. To understand the relationship between... -
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- Expression of Estrogen Receptor-beta and Its Variants in Normal Mammary and Tumor Tissues
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Kim KS, Heo MK, Kim SI, Park BW
- KMID: 2006626
- J Korean Breast Cancer Soc.
- 2003 Sep;6(3):161-167.
- doi: 10.4048/jkbcs.2003.6.3.161
PURPOSE: Since the discovery of estrogen receptor-beta(ER-beta, five C-terminal variants of ER-beta were identified. We designed this study to investigate the pattern and clinical implications of ER-betaand its splicing variants... -
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- Changes of Coregulators, MAP Kinase Activity and p27/kip1 with Estrogen or Antiestrogen Treatment in Breast Cancer Cell Line
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Park S, Heo MK, Lee MJ, Kim JH, Park BW
- KMID: 2241932
- J Breast Cancer.
- 2008 Jun;11(2):56-63.
- doi: 10.4048/jbc.2008.11.2.56
PURPOSE: Estrogen, various polypeptide hormones and growth factors are associated with the development and progression of breast cancer. Coregulatory proteins are also associated with estrogen receptor (ER) transcriptional activity and... -
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