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Hormonal Regulation of Hematopoietic Stem Cells and Their Niche: A Focus on Estrogen

Heo HR, Chen L, An B, Kim KS, Ji J, Hong SH

Self-renewal and differentiation are hallmarks of stem cells and controlled by various intrinsic and extrinsic factors. Increasing evidence indicates that estrogen (E2), the primary female sex hormone, is involved in...
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Cadmium-induced ER stress and inflammation are mediated through C/EBP–DDIT3 signaling in human bronchial epithelial cells

Kim J, Song H, Heo HR, Kim JW, Kim HR, Hong Y, Yang SR, Han SS, Lee SJ, Kim WJ, Hong SH

Cadmium (Cd), a major component of cigarette smoke, disrupts the normal functions of airway cells and can lead to the development of various pulmonary diseases such as chronic obstructive pulmonary...
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ACN9 Regulates the Inflammatory Responses in Human Bronchial Epithelial Cells

Jeong JH, Kim J, Kim J, Heo HR, Jeong JS, Ryu YJ, Hong Y, Han SS, Hong SH, Lee SJ, Kim WJ

BACKGROUND: Airway epithelial cells are the first line of defense, against pathogens and environmental pollutants, in the lungs. Cellular stress by cadmium (Cd), resulting in airway inflammation, is assumed to...
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