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Leukotriene B4 pathway regulates the fate of the hematopoietic stem cells

Chung JW, Kim GY, Mun YC, Ahn JY, Seong CM, Kim JH

  • KMID: 1033100
  • Exp Mol Med.
  • 2005 Feb;37(1):45-50.
Leukotriene B4(LTB4), derived from arachidonic acid, is a potent chemotactic agent and activating factor for hematopoietic cells. In addition to host defense in vivo, several eicosanoids have been reported to...
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Counteracting the enzymatic activity of dipeptidylpeptidase 4 for potential therapeutic advantage, with an emphasis on cord blood transplantation

Broxmeyer

Dipeptidylpeptidase (DPP) 4, also known as CD26, is an enzyme present on the surface of a number of different cell types. It is also found within cells and as a...
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Effect of Human Parathyroid Hormone on Hematopoietic Progenitor Cells in NOD/SCID Mice Co-Transplanted with Human Cord Blood Mononuclear Cells and Mesenchymal Stem Cells

Lim YJ, Hwang K, Kim M, Cho YH, Lee JH, Lee YH, Seo JJ

PURPOSE: We evaluated the effect of human parathyroid hormone (hPTH) on the engraftment and/or in vivo expansion of hematopoietic stem cells in an umbilical cord blood (UCB)-xenotransplantation model. In addition,...
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