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Hematopoietic stem cell mobilization: current status and future perspective

Kim JS

No abstract available.
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Bendamustine, etoposide, and dexamethasone to mobilize peripheral blood hematopoietic stem cells for autologous transplantation in non-Hodgkin lymphoma

Greenbaum , Green DJ, Holmberg L, Gooley T, Till BG, Budde LE, Rasmussen , Press OW, Gopal AK

BACKGROUND: Bendamustine is a chemotherapeutic agent that has shown broad activity in patients with lymphoid malignancies. It contains both alkylating and nucleoside analog moieties, and thus, is not commonly used...
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Factors Predicting Peripheral Blood Stem Cell Collection: Analysis of Korean Patients at a Single Center

Jang MJ, Cho D, Shin MG, Ryang DW

BACKGROUND: Peripheral blood stem cell (PBSC) transplantation is a curative treatment in various hematologic malignancies and some solid cancers. Effective mobilization and collection of PBSC is essential for successful PBSC...
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The possible cost effectiveness of peripheral blood stem cell mobilization with clophosphamide and the late addition of G-CSF

Min YJ, Kim SW, Suh C, Park J, Kim HJ, Kim JG, Kim TW, Lee JH, Kim SB, Lee KH, Lee JS, Kim WK, Kim SH

The purpose of this study was to develop a cost-effective protocol for the mobilization of peripheral blood stem cells (PBSC) in patients with malignancy. Thirty consecutive patients were randomized to...
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Determining the Optimal Time for Peripheral Blood Stem Cell Harvest by Detecting Immature Cells using Hematology Analyzer, SE-9000TM IMI Channel

Kim MJ, Lee SM, Lim JB, Lee KS, Park Q, Kim HO, Song KS

  • KMID: 2225862
  • Korean J Clin Pathol.
  • 1999 Apr;19(2):252-257.
BACKGROUND: A key to successful peripheral blood stem cell transplantation is to harvest a sufficient amount of hematopoietic stem cells. A method of quickly detecting hematopoietic stem cells in peripheral...
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The Effect of In Vivo Mobilization of Bone Marrow Stem Cells on the Pancreas of Diabetic Albino Rats (A Histological & Immunohistochemical Study)

Ismail ZM, Kamel AM, Yacoub MF, Aboulkhair AG

  • KMID: 1426171
  • Int J Stem Cells.
  • 2013 May;6(1):1-11.
BACKGROUND AND OBJECTIVES: The rapidly increasing number of diabetic patients across the world drew the attention to develop more effective therapeutic approaches. Recent investigations on newly differentiated insulin producing cells...
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Stem Cells and Lung Regeneration

El-Badrawy MK, Shalabi NM, Mohamed MA, Ragab A, Abdelwahab HW

Tissues such as the lung, liver, and pancreas that have a low steady-state cell turnover yet can respond robustly after injury to replace damaged cells. The airway epithelium is exposed...
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Intramarrow injection of beta-catenin-activated, but not naive mesenchymal stromal cells stimulates self-renewal of hematopoietic stem cells in bone marrow

Ahn JY, Park G, Shim JS, Lee JW, Oh IH

Bone marrow mesenchymal stromal cells (MSCs) have been implicated in the microenvironmental support of hematopoietic stem cells (HSCs) and often co-transplanted with HSCs to facilitate recovery of ablated bone marrows....
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Prognostic Factors in Non-Hodgkin's Lymphoma Patients Treated by Autologous Stem Cell Transplantation: A Single Center Experience

Suh C, Kim SH, Kim HJ, Jang G, Kim EK, Ko OB, Kim S, Sohn HJ, Lee JS, Kim W, Huh J

  • KMID: 2166119
  • Cancer Res Treat.
  • 2005 Oct;37(5):294-301.
PURPOSE: Autologous stem cell transplantation (ASCT) is increasingly used in patients with non-Hodgkin's lymphoma (NHL). Various clinical parameters-were evaluated to obtain significant predictors of the outcome following ASCT in patients...
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The Correlation between G-CSF Dosage and the Number of Collected CD34+ Cells in Pediatric Patients Undergoing Peripheral Blood Stem Cell Mobilization

Lee JS, Jung HJ, Park JE

BACKGROUND: In high risk malignancies of pediatric patients, many investigators have explored the use of stronger myeloablative regimens with autologous peripheral blood stem cell rescue such as the Tandem protocol....
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Plerixafor use for peripheral blood stem cell mobilization in Korea

Kim SJ, Yoon DH, Yang DH, Eom HS, Cho SG, Yoon SS, Lee JH, Kim WS, Suh C

No abstract available.
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Cutoff Value of PB CD34+ Cells for Optimization of PBSC Collection

Lee HJ, Shin KH, Song D, Kim SY, Kim HH, Lee EY, Son HC

  • KMID: 2300015
  • Korean J Blood Transfus.
  • 2011 Apr;22(1):46-53.
BACKGROUND: Peripheral hematopoietic stem cell mobilization is increasing due to its advantages. For successful engraftment, obtaining sufficient stem cells is prerequisite. The number of CD34+ cells of collected blood are...
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Differences in Mobilization Efficiency between Small Children and Adults with Healthy Marrows

Shin EK, Kim DY, Rah WJ, Koh H, Suh JY, Chang M, Nam E, Lee YH

BACKGROUND: We compared the yields of mobilized PBSCs from single day of normal volume leukapheresis (NVL) in children and adults, and factors affecting the yields, to understand differences in mobilization...
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The effect of the dexamethasone, cytarabine, and cisplatin (DHAP) regimen on stem cell mobilization and transplant outcomes of patients with non-Hodgkin's lymphoma who are candidates for up-front autologous stem cell transplantation

Jeon SY, Yhim HY, Kim HS, Kim JA, Yang DH, Kwak JY

BACKGROUND/AIMS: Data on dexamethasone, cytarabine, and cisplatin (DHAP) as a mobilization regimen, compared to high-dose cyclophosphamide (HDC), for up-front autologous stem cell transplantation (ASCT) in non-Hodgkin’s lymphoma (NHL) is limited. METHODS:...
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Allogeneic Peripheral Blood Stem Cell Transplantation in Hematological Malignancies: Stem Cell Mobilization with GM-CSF alone or a combination of GM-CSF and G-CSF from Normal Healthy Donors

Kwak DS, Lee YT, Chae YS, Seo KW, Park SW, Baek JH, Kim JG, Kim DH, Jung JT, Park SH, Sohn SK, Suh JS, Lee KB

  • KMID: 2083425
  • Korean J Hematol.
  • 2001 Feb;36(1):25-34.
BACKGROUND: Granulocyte-colony stimulating factor (G-CSF) has been used in normal heathy donors to mobilize hematopoietic progenitors. Recently, it was reported that an addition of granulocyte-macrophage-CSF (GM-CSF) mobilized more primitive CD34+...
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Correlation between the Severity of Bone Pain and the Amount of CD34+ Cells after Peripheral Blood Stem Cell Mobilization

Seo JW, Choi JS, Kim YH, Yoon SS, Park S, Han KS

BACKGROUND: Peripheral blood stem cells (PBSCs) are mobilized by granulocyte-colony stimulating factor (G-CSF), which causes several side effects in allogeneic donors. We report on side effects of G-CSF administration and...
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The Effect of Overnight Storage of Cord Bloods on Cell Viability, Live CD34 Cell Fraction, and Clonogenic Potential under Different Storage Conditions

Yoo KH, Koh SH, Park ES, Han KS, Shin HY, Ahn HS

  • KMID: 2278225
  • Korean J Pediatr Hematol Oncol.
  • 2001 Apr;8(1):90-100.
PURPOSE: In children, at least two or more stem cell mobilization processes are needed in autologous peripheral blood stem cell transplantation to prevent delayed engraftment. And to decrease the risk...
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Clinical Usefulness of the Hematopoietic Progenitor Cell Counts in Predicting the Optimal Timing of Peripheral Blood Stem Cell Harvest

Lee JL, Kim SB, Lee GW, Ryu MH, Kim EK, Kim S, Kim WK, Lee JS, Park KU, Suh C

Although enumeration of CD34+ cells in the peripheral blood (PB) on the day of apheresis predicts the quantity of those cells collected, the flow cytometric techniques used are complex and...
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Retrospective Analysis of Peripheral Blood Stem Cell Transplantation for the Treatment of High-Risk Neuroblastoma

Kim EK, Kang HJ, Park JA, Choi HS, Shin HY, Ahn HS

Disease relapse after autologous peripheral blood stem cell transplantation (APBSCT) is the main cause of treatment failure in high-risk neuroblastoma (NBL). To reduce relapse, various efforts have been made such...
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Transplantation of peripheral blood stem cells mobilized by intensified consolidation and granulocyte colony-stimulating factor in acute leukemia

Min YH, Lee ST, Kim JS, Jang JH, Suh HC, Kim HO, Hahn JS, Ko YW

The purpose of this study was to evaluate the feasibility and efficacy of autologous transplantation of peripheral blood stem cells (PBSC) mobilized with high-dose consolidation chemotherapy and...
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