- Effects of propofol on beta-adrenoceptor-mediated signal transduction in cardiac muscle; role of cAMP
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Chang CH, Roh GU, Park WK
- KMID: 2299336
- Korean J Anesthesiol.
- 2010 Apr;58(4):374-377.
- doi: 10.4097/kjae.2010.58.4.374
BACKGROUND: Propofol may decrease myocardial contractility via actions on the beta-adrenoceptor-mediated signal transduction. The aim of this study was to evaluate the effect of propofol via beta-adrenoceptor-mediated signal transduction by... -
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- Effect of ATP on Calcium Channel Modulation in Rat Adrenal Chromaffin Cells
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Kim KA, Goo YS
- KMID: 1910548
- Prog Med Phys.
- 2014 Sep;25(3):157-166.
- doi: 10.14316/pmp.2014.25.3.157
ATP in quantity co-stored with neurotransmitters in the secretory vesicles of neurons, by being co-released with the neurotransmitters, takes an important role to modulate the stimulus-secretion response of neurotransmitters. Here,... -
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- Studies of G Protein Activation of Orphanin FQ in the Cerebrum, Thalamus and Spinal Cord of Monkeys
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Lee H, Han JI
- KMID: 2032606
- Korean J Anesthesiol.
- 2004 Dec;47(6):877-882.
- doi: 10.4097/kjae.2004.47.6.877
BACKGROUND: The aim of this in vitro study was to investigate [35S]GTP gamma S binding stimulated activation by orphanin FQ in monkey cerebral, thalamic, and spinal membranes. METHODS: A rhesus monkey... -
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- Investigation of Orphanin FQ-stimulated [35S]GTPgammaS Binding in the Whole Brain of Mice: Does Orphanin FQ Have Anti-opioid Effect in the Level of Receptor-ligand Interaction and [35S]GTPgammaS Activation?
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Lee H, Lee EM
- KMID: 2238304
- Korean J Anesthesiol.
- 2007 Jul;53(1):91-96.
- doi: 10.4097/kjae.2007.53.1.91
BACKGROUND: This study was examined whether or not the orphanin FQ (OFQ)-stimulated [35S]GTPgammaS activity interact with DAMGO in the whole brain of mice. METHODS: ICR mice (male, n = 20,... -
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- Dynorphin A (1-17) was Selective tomicro-Opioid Receptor in Agonist-Stimulated [35S] GTPgammaS Binding in Cortical and Thalamic Membranes of Monkey
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Lee H, Lee SA, Kang SY, Kim DY, Kim CH
- KMID: 2032239
- Korean J Anesthesiol.
- 2005 Apr;48(4):412-416.
- doi: 10.4097/kjae.2005.48.4.412
BACKGROUND: Dynorphin A (1-17) is conceived as an endogenous opioid peptide with a high degree of selectivity forkappa- opioid receptor even though it has been reported to sometimes act like... -
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- Partial purification of protein farnesyl cysteine carboxyl methyltransferase from bovine brain
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Yoo BC, Kang MS, Kim SD, Lee YS, Choi SY, Ryu CK, Park GH, Han JS
- KMID: 755013
- Exp Mol Med.
- 1998 Dec;30(4):227-234.
C-terminal farnesyl cysteine carboxyl methylation has been known to be the last step in the post-translational modification processes of several important signal transduction proteins in eukaryotes including ras related GTP... -
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- A new member of alpha 1-adrenoceptor-coupled G alpha h (transglutaminase II) family in pig heart: purification and characterization
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Yoo SM, Jeong HS, Han KJ, Cho SH, Lee HS, Yun HY, Kwon NS, Baek KJ
- KMID: 754992
- Exp Mol Med.
- 1998 Jun;30(2):81-86.
We previously reported an identification of a 77-kDa GTP-binding protein that co-purified with the alpha 1-adrenoceptor following ternary complex formation. In the present paper, we report on the purification and characterization of... -
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- The nuclear 16-kD protein methylation increases in the early period of liver regeneration in a hepatectomized rat
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Lee K, Lee KM, Kim TJ, Han JS, Kim MK, Hong YS, Park GH, Lee KW
- KMID: 1103324
- Exp Mol Med.
- 2004 Dec;36(6):563-571.
Methylation events play a critical role in various cellular processes including regulation of gene transcription and proliferation. We observed that methyltransferase activity underwent time-dependent changes in the cytosol of the... -
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- The proteins of synaptic vesicle membranes are affected during ageing of rat brain
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Lee SR, Kim AR, Kim JS, Kim JB, Lee JY, Lee YL, Choe M, Park JB
- KMID: 1457533
- Exp Mol Med.
- 2001 Dec;33(4):220-225.
Low molecular weight GTP-binding proteins are molecular switches that are believed to play pivotal roles in cell growth, differentiation, cytoskeletal organization, and vesicular trafficking. Rab proteins are key players in... -
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