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The Uric Acid and Gout have No Direct Causality With Osteoarthritis: A Mendelian Randomization Study

Lee YH, Song GG

OBJECTIVE: To examine whether uric acid level or gout is causally associated with the risk of osteoarthritis. METHODS: We performed a two-sample Mendelian randomization (MR) analysis using inverse-variance weighted (IVW), MR-Egger...
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What is the Best Choice for Urate-lowering Therapy for Korean?

Cheon YH, Song JS

Gout is one of the most common forms of acute inflammatory arthritis caused by long-standing hyperuricemia. Various clinical and epidemiological studies have demonstrated that uric acid, which is strongly associated...
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The Relationship between Pulmonary Function and Serum Uric Acid Level in the Korean Population

Kim GT, Sull JW

BACKGROUND: Forced vital capacity (FVC), forced expiratory volume in the first second (FEV₁), and the ratio of FEV₁ to FVC (FEV₁/FVC) are considered as the major spirometry parameters. Serum uric...
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Pathological Fracture of the Femoral Neck due to Tophaceous Gout: An Unusual Case of Gout

Jeon YS, Hwang DS, Hwang JM, Lee JK, Park YC

A 48-year-old man visited the emergency room with right hip pain that started abruptly while walking out of the bathroom. Computed tomography showed an intraosseous mass in the femoral neck....
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Symptomatic Tophaceous Gout in the Bilateral Patellae

Kim DG, Ahn GY

Tophaceous gout is an inflammatory arthropathy caused by hyperuricemia. Gout shows typically episodic acute and chronic pain with arthritis due to synovitis induced by deposition of monosodium urate crystals. Tophus...
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Prominent Inflammatory Features of Monocytes/Macrophages in Acute Calcium Pyrophosphate Crystal Arthritis: a Comparison with Acute Gouty Arthritis

Jeong JH, Jung JH, Lee JS, Oh JS, Kim YG, Lee CK, Yoo B, Hong S

Calcium pyrophosphate (CPP) crystals can present as acute inflammatory arthritis which is known as an acute CPP crystal arthritis. Although monocytes/macrophages have been shown to play a role in the...
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Relationship between Urate Crystal Deposits Detected by Dual-energy Computed Tomography and Bone Erosions in Symptomatic Gout Patients without Clinically Apparent Tophi

Chung MK, Kim IJ, Hyun H, Hwang JY, Lee J

OBJECTIVE: Dual-energy computed tomography (DECT) allows sensitive detection of monosodium urate (MSU) crystal deposits in gout. However, the role of MSU deposits on DECT during the disease process of gout...
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Comparison of Efficacy and Safety of Febuxostat in Gout Patients with Chronic Kidney Disease Stage 3 and Stage 4/5

Ahn E, Lee S, Lee HN, Lee SG, So MW

OBJECTIVE: To compare efficacy and safety of febuxostat in gouty patients with chronic kidney disease (CKD) stage 3 and stage 4/5. METHODS: Age and sex matched patients with CKD stage 3...
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Giant Tophi Involving Both Suprapatellar Pouches and Upper Poles of the Patellae: Treatment with Febuxostat and the 6 Years Follow-Up

Kim ST, Lee SY, Kim SJ, Kim BS

Tophi is one of the clinical manifestations of gout. On the other hand, it does not draw the patient's attention when it is asymptomatic, which leads to delayed management. The...
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Osteoclasts in the Inflammatory Arthritis: Implications for Pathologic Osteolysis

Jung YK, Kang YM, Han S

The enhanced differentiation and activation of osteoclasts (OCs) in the inflammatory arthritis such as rheumatoid arthritis (RA) and gout causes not only local bone erosion, but also systemic osteoporosis, leading...
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Insulin resistance is an independent predictor of erectile dysfunction in patients with gout

Kim JH, Chung MK, Kang JY, Koh JH, Lee J, Kwok SK, Ju JH, Park SH

BACKGROUND/AIMS: Gout is associated with metabolic disorders that are important risk factors for cardiovascular disease and erectile dysfunction (ED). We aimed to identify independent predictors of ED in patients with...
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Traumatic Separation of Bipartite Patella Underlying Gout

Choi ES, Sim JA, Go JY, Na YG

Gouty arthritis is a common crystal arthropathy, but gout tophus in the bipartite patella is a rare condition. This report presented a traumatic separation of bipartite patellar fragment caused by...
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Surgical Treatment of Chronic Tophaceous Gout in the 1st Metatarso-Phalangeal Joint

Lee TH, Nam IH, Ahn GY, Lee YH, Lee YS, Choi YD, Lee HH

PURPOSE: Chronic tophaceous gout is a painful and disabling inflammatory disease. Surgical treatment for chronic tophaceous gout is very difficult with many complications. This study evaluated the efficacy of shortening...
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Chronic Multiple Gouty Arthritis Diagnosed during Anti-Tuberculosis Treatment of Recurrent Tuberculous Arthritis: A Case Report

Oh HC, Choi YJ, Ha JW, Park SH, Kim SH, Yoon HK

Gout occurs mainly in monoarthritis and is found in more than 50% of cases in hallux of the foot. In addition, symptoms sometimes begin in the hand, wrist, and elbow,...
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New Classification Criteria and Guideline for Management of Gout

Song JS

Gout is a chronic systemic metabolic disease characterized by recurrent attacks of inflammatory arthritis resulting from the precipitation of monosodium urate crystals, which has various clinical and pathological manifestations. The...
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Metabolic syndrome: prevalence and risk factors in Korean gout patients

Jung JH, Song GG, Ji JD, Lee YH, Kim JH, Seo YH, Choi SJ

BACKGROUND/AIMS: We performed this study to investigate associations between metabolic syndrome, chronic kidney disease (CKD), and gout. METHODS: We reviewed the medical records of 151 patients with gout at the Department...
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Hypouricemic Effect of Ethanol Extract of Aster glehni Leaves in Potassium Oxonate-Induced Hyperuricemic Rats

Park JE, Yeom Z, Park KT, Han EH, Yu HJ, Kang HS, Lim YH

The prevalence of gout is increasing worldwide, and control of serum uric acid level has been regarded as one of the therapeutic methods for gout. Inhibition of xanthine oxidase (XO)...
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Is the Serum Uric Acid Level Independently Associated with Incidental Urolithiasis?

Lim DH, Kim MH, Hong S, Kim YG, Lee CK, Choi SW, Yoo B, Oh JS

OBJECTIVE: Urolithiasis is one of the manifestations of gout and the risk is higher in gouty patients. On the other hand, an independent association between the urinary stone and serum...
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Tophaceous Gout of the Lumbar Spine Mimicking Infectious Spondylodiscitis and Epidural Abscess

Jeong JS, Jeong HT, Lee IS, Woo YH

STUDY DESIGN: Case report OBJECTIVES: We report a case of surgically proven tophaceous gout of the lumbar spine at the L5-S1 level in a 43-year-old man that mimicked infectious spondylodiscitis and...
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Prescription pattern of urate-lowering therapy in Korean gout patients: data from the national health claims database

Kim JW, Kwak SG, Park SH

No abstract available.
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