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Circulating Total Glutathione in Normal Tension Glaucoma Patients: Comparison with Normal Control Subjects

Park MH, Moon J

PURPOSE: Oxidative stress plays a critical role in the pathogenesis of glaucoma. Glutathione is a major antioxidant molecule present in intracellular or extracellular space. Herein, we aimed to examine circulating...
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Aspartate modulates the ethanol-induced oxidative stress and glutathione utilizing enzymes in rat testes.

Oh SI, Lee MS, Kim CI, Song KY, Park SC

  • KMID: 1093597
  • Exp Mol Med.
  • 2002 Mar;34(1):47-52.
In order to develop a preventive strategy against ethanol-induced oxidative damages on various tissues and organs, we have examined the protective effect of aspartate on the pathogenesis of testes in...
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Glutathione Levels in Helicobacter pylori-infected Gastric Mucosa

Park DK, Jeong SK, Chung MG, Kwon OS, Kim SS, Koo YS, Kim YK, Kim YS, Choi DJ, Park CS, Chung WG, Kim JH

  • KMID: 772556
  • Korean J Gastroenterol.
  • 2003 Oct;42(4):267-273.
BACKGROUND/AIMS: Oxidative stress may contribute to gastric epithelial damage and mutagenesis caused by Helicobacter pylori (H. pylori). H. pylori induces recruitment and activation of inflammatory cells, which produces reactive oxygen...
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Lack of Association of Glutathione S-transferase P1 Ile105Val Polymorphism with Aspirin-Intolerant Asthma

Oh JM, Kim SH, Suh CH, Nahm DH, Park HS, Lee YM, Lee JH, Park CS, Shin HD

BACKGROUND: Glutathion S-transferase P1 (GSTP1), the abundant isoform of glutathione S-transferase in lung epithelium, plays an important role in cellular protection against oxidative stress and toxic foreign chemicals. GSTP1 (Ile105Val)...
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Rapid uptake of oxidized ascorbate induces loss of cellular glutathione and oxidative stress in liver slices

Song JH, Simons C, Cao L, Shin SH, Hong M, Chung IM

  • KMID: 1097253
  • Exp Mol Med.
  • 2003 Apr;35(2):67-75.
The observation that ascorbate known to retain pro-oxidant properties induces cell death in a number of immortal cell lines, led us to examine its mechanism and whether it is involved...
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Bucillamine prevents cisplatin-induced ototoxicity through induction of glutathione and antioxidant genes

Kim SJ, Hur JH, Park C, Kim HJ, Oh GS, Lee JN, Yoo SJ, Choe SK, So HS, Lim DJ, Moon SK, Park R

Bucillamine is used for the treatment of rheumatoid arthritis. This study investigated the protective effects of bucillamine against cisplatin-induced damage in auditory cells, the organ of Corti from postnatal rats...
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