- The Effect of Anoxia on the Amino Acid and Carbohydrate Metabolism of the Isolated Dog Brain
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Huh K, Gilboe DD, Minsker DH
- KMID: 1106108
- Yonsei Med J.
- 1967 Dec;8(1):13-17.
- doi: 10.3349/ymj.1967.8.1.13
The isolated dog brain was perfused for a period of 4 minutes with blood normal in all constituents, but pathologically low in oxygen in order to follow the metabolic response... -
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- Modulation of the caveolin-3 and Akt status in caveolae by insulin resistance in H9c2 cardiomyoblasts
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Ha H, Pak Y
- KMID: 1056228
- Exp Mol Med.
- 2005 Jun;37(3):169-178.
We investigated glucose uptake and the translocation of Akt and caveolin-3 in response to insulin in H9c2 cardiomyoblasts exposed to an experimental insulin resistance condition of 100 nM insulin in... -
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- Effect of the combination of metformin and fenofibrate on glucose homeostasis in diabetic Goto-Kakizaki rats
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Oh TJ, Shin JY, Kang GH, Park KS, Cho YM
- KMID: 2154249
- Exp Mol Med.
- 2013 Jul;45(7):e30.
Metformin has been reported to increase the expression of the glucagon-like peptide-1 (GLP-1) receptor in pancreatic beta cells in a peroxisome proliferator-activated receptor (PPAR)-alpha-dependent manner. We investigated whether a PPARalpha... -
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- Regulation of glucose metabolism-related genes and VEGF by HIF-1alpha and HIF-1beta, but not HIF-2alpha, in gastric cancer
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Song IS, Wang AG, Yoon SY, Kim JM, Kim JH, Lee DS, Kim NS
- KMID: 756286
- Exp Mol Med.
- 2009 Jan;41(1):51-58.
- doi: 10.3858/emm.2009.41.1.007
Hypoxia-inducible factors (HIFs) are transcription factors that activate the transcription of target genes involved in crucial aspects of cancer development. This study investigated the expression of HIFs and their contribution... -
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- Parameters of Glucose and Lipid Metabolism Affect the Occurrence of Colorectal Adenomas Detected by Surveillance Colonoscopies
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Kim NH, Suh JY, Park JH, Park DI, Cho YK, Sohn CI, Choi K, Jung YS
- KMID: 2427123
- Yonsei Med J.
- 2017 Mar;58(2):347-354.
- doi: 10.3349/ymj.2017.58.2.347
PURPOSE: Limited data are available regarding the associations between parameters of glucose and lipid metabolism and the occurrence of metachronous adenomas. We investigated whether these parameters affect the occurrence of... -
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- Resveratrol stimulates glucose transport in C2C12 myotubes by activating AMP-activated protein kinase
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Park CE, Kim MJ, Lee JH, Min BI, Bae H, Choe W, Kim SS, Ha J
- KMID: 1094663
- Exp Mol Med.
- 2007 Apr;39(2):222-229.
trans-Resveratrol (t-RVT), a naturally occurring polyphenol found in Polygonum cuspidatum, grape, and red wine, has been reported to have anti- inflammatory, cardioprotective, and cancer chemopreventive properties. However antidiabetic effect of... -
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- Molecular Mechanism of Insulin Resistance in Obesity and Type 2 Diabetes
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Choi K, Kim YB
- KMID: 1785667
- Korean J Intern Med.
- 2010 Jun;25(2):119-129.
- doi: 10.3904/kjim.2010.25.2.119
Insulin resistance is a major risk factor for developing type 2 diabetes caused by the inability of insulin-target tissues to respond properly to insulin, and contributes to the morbidity of... -
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- Basal Forebrain Cholinergic Deficits Reduce Glucose Metabolism and Function of Cholinergic and GABAergic Systems in the Cingulate Cortex
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Jeong DU, Oh JH, Lee JE, Lee J, Cho ZH, Chang JW, Chang WS
- KMID: 2466366
- Yonsei Med J.
- 2016 Jan;57(1):165-172.
- doi: 10.3349/ymj.2016.57.1.165
PURPOSE: Reduced brain glucose metabolism and basal forebrain cholinergic neuron degeneration are common features of Alzheimer's disease and have been correlated with memory function. Although regions representing glucose hypometabolism in... -
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- The Inhibitory Effect of siRNAs on The High Glucose-Induced Overexpression of TGF-beta1 in Mesangial Cells
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Noh HJ, Kim HC, Lee SS, Kang YN, Chae YM, Park KK
- KMID: 1778423
- J Korean Med Sci.
- 2006 Jun;21(3):430-435.
- doi: 10.3346/jkms.2006.21.3.430
Diabetic nephropathy is characterized by an expansion of the glomerular mesangium, caused by mesangial cell proliferation and an excessive accumulation of extracellar matrix (ECM) proteins, which eventually leading to glomerulosclerosis.... -
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- Aging impairs insulin-stimulated glucose uptake in rat skeletal muscle via suppressing AMPKalpha
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Qiang W, Weiqiang K, Qing Z, Pengju Z, Yi L
- KMID: 756077
- Exp Mol Med.
- 2007 Aug;39(4):535-543.
Insufficient intracellular fat oxidation is an important contributor to aging-related insulin resistance, while the precise mechanism underlying is unclear. AMP-activated protein kinase (AMPK) is an important regulator of intracellular fat... -
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- Differences in Regional Glucose Metabolism of the Brain Measured with F-18-FDG-PET in Patients with Essential Tremor According to Their Response to Beta-Blockers
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Song IU, Ha SW, Yang YS, Chung YA
- KMID: 2160763
- Korean J Radiol.
- 2015 Oct;16(5):967-972.
- doi: 10.3348/kjr.2015.16.5.967
OBJECTIVE: In this study, there was an investigation as to whether there is a functional difference in essential tremor (ET), according to responses to beta-blockers, by evaluating regional changes in... -
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- Postpartum Glucose Testing Rates Following Gestational Diabetes Mellitus and Factors Affecting Testing Non-compliance from Four Tertiary Centers in Korea
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Cho GJ, An JJ, Choi SJ, Oh SY, Kwon HS, Hong SC, Kwon JY
- KMID: 2359970
- J Korean Med Sci.
- 2015 Dec;30(12):1841-1846.
- doi: 10.3346/jkms.2015.30.12.1841
The purpose of this study was to investigate postpartum glucose testing rates in patients with gestational diabetes mellitus (GDM) and to determine factors affecting testing non-compliance in the Korean population.... -
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- Relations between Long-term Glycemic Control and Postoperative Wound and Infectious Complications after Total Knee Arthroplasty in Type 2 Diabetics
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Han HS, Kang SB
- KMID: 1705532
- Clin Orthop Surg.
- 2013 Jun;5(2):118-123.
- doi: 10.4055/cios.2013.5.2.118
BACKGROUND: The authors examined whether poor preoperative glucose control, as indicated by the hemoglobin A1c (HbA1c) level of more than 8%, is associated with postoperative wound and infectious complications in... -
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- Emodin ameliorates high-glucose induced mesangial p38 over-activation and hypocontractility via activation of PPARgamma
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Liu Y, Jia L, Liu ZC, Zhang H, Zhang PJ, Wan Q, Wang R
- KMID: 756208
- Exp Mol Med.
- 2009 Sep;41(9):648-655.
- doi: 10.3858/emm.2009.41.9.071
Early stage diabetic nephropathy is characterized by elevated glomerular filtration. Recent studies have identified high-glucose induced p38 MAPK (p38) over-activation in mesangial cells. Mesangial hypocontractility is the major underlying mechanism,... -
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- Does Abdominal Obesity Accelerate the Effect of Hypertriglyceridemia on Impaired Fasting Glucose?
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Lee S, Chun K, Lee S, Kim D
- KMID: 1074987
- Yonsei Med J.
- 2010 May;51(3):360-366.
- doi: 10.3349/ymj.2010.51.3.360
PURPOSE: This study sought to determine whether abdominal obesity is a risk factor for impaired fasting glucose (IFG) and hypertriglyceridemia and to verify whether moderate effect of abdominal obesity on... -
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- A Telephone-Delivered Intervention to Improve Glycemic Control in Type 2 Diabetic Patients
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Oh JA, Kim HS, Yoon KH, Choi ES
- KMID: 1719062
- Yonsei Med J.
- 2003 Feb;44(1):1-8.
- doi: 10.3349/ymj.2003.44.1.1
This study was performed to investigate the effect of a telephone-delivered intervention on glycemic control and body mass index in Korean type 2 diabetic patients. 38 patients were randomly selected,... -
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- Anti-Proliferative Effects of Rutin on OLETF Rat Vascular Smooth Muscle Cells Stimulated by Glucose Variability
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Yu SH, Yu JM, Yoo HJ, Lee SJ, Kang DH, Cho YJ, Kim DM
- KMID: 2374042
- Yonsei Med J.
- 2016 Mar;57(2):373-381.
- doi: 10.3349/ymj.2016.57.2.373
PURPOSE: Proliferation of vascular smooth muscle cells (VSMCs) plays a crucial role in atherosclerosis. Rutin is a major representative of the flavonol subclass of flavonoids and has various pharmacological activities.... -
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- Estimating Average Glucose Levels from Glycated Albumin in Patients with End-Stage Renal Disease
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Kim JK, Park JT, Oh HJ, Yoo DE, Kim SJ, Han SH, Kang SW, Choi KH, Yoo TH
- KMID: 1776994
- Yonsei Med J.
- 2012 May;53(3):578-586.
- doi: 10.3349/ymj.2012.53.3.578
PURPOSE: In patients with diabetic end stage renal disease (ESRD), glycated albumin (GA) reflects recent glycemic control more accurately than glycated hemoglobin (HbA1c). We evaluated the relationship between GA and... -
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- Insulin-dependent suppression of cholesterol 7alpha-hydroxlase is a possible link between glucose and cholesterol metabolisms
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Park WH, Pak YK
- KMID: 1123369
- Exp Mol Med.
- 2011 Oct;43(10):571-579.
- doi: 10.3858/emm.2011.43.10.064
Cholesterol 7alpha-hydroxylase (CYP7A1) regulates the balance between cholesterol supply and metabolism by catalyzing the rate-limiting step of bile acid biosynthesis. The transcriptional activity of CYP7A1 is tightly controlled by various... -
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- Characteristics Predictive for a Successful Switch from Insulin Analogue Therapy to Oral Hypoglycemic Agents in Patients with Type 2 Diabetes
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Kim G, Lee YH, Kang ES, Cha BS, Lee HC, Lee BW
- KMID: 2427157
- Yonsei Med J.
- 2016 Nov;57(6):1395-1403.
- doi: 10.3349/ymj.2016.57.6.1395
PURPOSE: The objective of this study was to investigate clinical and laboratory parameters that could predict which patients could maintain adequate glycemic control after switching from initial insulin therapy to... -
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