- Interleukin-10 Promoter Polymorphism is Associated with the Predisposition to the Development of IgA Nephropathy and Focal Segmental Glomerulosclerosis in Korea
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Chin HJ, Na KY, Kim SJ, Oh KH, Kim YS, Lim CS, Kim S, Chae DW
- KMID: 2157750
- J Korean Med Sci.
- 2005 Dec;20(6):989-993.
- doi: 10.3346/jkms.2005.20.6.989
The roles of interleukin-10 (IL-10) have been emphasized in several models of glomerulonephritis (GN). Three biallelic polymorphisms within the IL-10 promoter region, at positions -1,082, -819, and -592 from the... -
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- The enabled homolog gene polymorphisms are associated with susceptibility and progression of childhood IgA nephropathy
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Hahn WH, Suh JS, Cho BS, Kim SD
- KMID: 1122280
- Exp Mol Med.
- 2009 Nov;41(11):793-801.
- doi: 10.3858/emm.2009.41.11.085
The enabled homolog gene (ENAH, hMena) is abundantly expressed in mesangial tissue, and might play an important role in inflammatory processes of IgA nephropathy (IgAN). The present study was conducted... -
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- Is Tumor Necrosis Factor Genotype (TNFA2/TNFA2)a Genetic Prognostic Factor of an Unfavorable Outcome in IgA Nephropathy?
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Lee EY, Yang DH, Hwang KY, Hong SY
- KMID: 648357
- J Korean Med Sci.
- 2001 Dec;16(6):751-755.
- doi: 10.3346/jkms.2001.16.6.751
The purpose of this study was to examine whether there are the associations between TNF alpha and TNF beta gene polymorphisms and the development and progression of Ig A nephropathy... -
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- The Heme Oxygenase-1 Genotype is a Risk Factor to Renal Impairment of IgA Nephropathy at Diagnosis, Which is a Strong Predictor of Mortality
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Chin HJ, Cho HJ, Lee TW, Na KY, Yoon HJ, Chae DW, Kim S, Jeon US, Do JY, Park JW, Yoon KW, Shin YT, Lee KW, Na KR, Cha DR, Kang YS, The Progressive REnal disease and Medical Informatics and gEnomics Research (PREMIER) members
- KMID: 1778137
- J Korean Med Sci.
- 2009 Jan;24(Suppl 1):S30-S37.
- doi: 10.3346/jkms.2009.24.S1.S30
The induction of heme oxygenase-1 (HO-1) ameliorates oxidative stress and inflammatory process, which play important roles in IgA nephropathy. We hypothesized length polymorphism in the promoter region of the HO-1... -
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- CpG Array Analysis of Histone H3 Lysine 4 Trimethylation by Chromatin Immunoprecipitation Linked to Microarrays Analysis in Peripheral Blood Mononuclear Cells of IgA Nephropathy Patients
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Qi S, Sui W, Yang M, Chen J, Dai Y
- KMID: 1120206
- Yonsei Med J.
- 2012 Mar;53(2):377-385.
- doi: 10.3349/ymj.2012.53.2.377
PURPOSE: The purpose of the present study was to investigate the aberrance of histone H3 lysine 4 trimethylation (H3K4me3) in patients with IgA Nephropathy (IgAN). MATERIALS AND METHODS: In this study,... -
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