- Paricalcitol prevents MAPK pathway activation and inflammation in adriamycin-induced kidney injury in rats
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Deluque AL, Almeida LFd, Oliveira BM, Souza CS, Maciel ALD, Francescato HDC, Giovanini C, Costa RS, Coimbra TM
- KMID: 2559067
- J Pathol Transl Med.
- 2024 Sep;58(5):219-228.
- doi: 10.4132/jptm.2024.07.12
Background: Activation of the mitogen-activated protein kinase (MAPK) pathway induces uncontrolled cell proliferation in response to inflammatory stimuli. Adriamycin (ADR)-induced nephropathy (ADRN) in rats triggers MAPK activation and pro-inflammatory mechanisms... -
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