- Host Immune Responses to Intradiscal Gene Transfer
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Moon SH, Kim H, Kwon EH, Park EH, Lee HM, Hahn SB, Kim NH, Gilbertson LG, Kang JD
- KMID: 2322876
- J Korean Soc Spine Surg.
- 2002 Jun;9(2):84-90.
PURPOSE: To elucidate host immune responses to intradiscal gene transfer. MATERIALS AND METHODS: Twenty rabbits were utilized. Ad/luciferase (adenovirus construct) were injected into nucleus pulposus of lumbar vertebrae. Group 1 received... -
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- Matrix Synthesis of Human Intervertebral Disc Cells: Effect of Gene Transfer, Exogenous Growth Factor, Incubation Period, and Culture Methods
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Moon SH, Park MS, Lee HM, Kang ES, Kim NH, Gilbertson LG, Kang JD
- KMID: 2322859
- J Korean Soc Spine Surg.
- 2001 Dec;8(4):447-454.
STUDY DESIGN: In vitro experiment to determine the matrix synthesis of intervertebral disc (IVD) cell to various biologic interventions and conditions. OBJECTIVES: To elucidate biologic responses in terms of matrix synthesis... -
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- Intradiscal Gene Therapy: Therapeutic Implications in Degenerative Disc Disease
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Moon SH, Park MS, Kang YH, Kim HJ, Lee HM, Kim NH, Gilbertson LG, Kang JD
- KMID: 2097716
- J Korean Soc Spine Surg.
- 2000 Dec;7(4):507-513.
STUDY DESIGN: In vitro and in vivo studies to determine the anabolic effects of intervertebral disc (IVD) to adenovirus-mediated therapeutic gene transfer. OBJECTIVES: To quantify the anabolic effect of human IVD... -
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