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Editor’s introduction to this issue (G&I 20:4, 2022)

Park T

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Overview of frequent pattern mining

Ott J, Park T

Various methods of frequent pattern mining have been applied to genetic problems, specifically, to the combined association of two genotypes (a genotype pattern, or diplotype) at different DNA variants with...
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Antimicrobial resistance in Klebsiella pneumoniae: identification of bacterial DNA adenine methyltransferase as a novel drug target from hypothetical proteins using subtractive genomics

Omeershffudin UNM, Kumar S

Klebsiella pneumoniae is a gram-negative bacterium that is known for causing infection innosocomial settings. As reported by the World Health Organization, carbapenem-resistantEnterobacteriaceae, a category that includes K. pneumoniae, are classified...
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Beta-Meta: a meta-analysis application considering heterogeneity among genome-wide association studies

Kim G, Lee Y, Park JH, Kim D, Lee W

Many packages for a meta-analysis of genome-wide association studies (GWAS) have beendeveloped to discover genetic variants. Although variations across studies must be considered, there are not many currently-accessible packages that...
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The pattern of coding sequences in the chloroplast genome of Atropa belladonna and a comparative analysis with other related genomes in the nightshade family

Sahoo S, Rakshit R

Atropa belladonna is a valuable medicinal plant and a commercial source of tropane alkaloids, which are frequently utilized in therapeutic practice. In this study, bioinformaticmethodologies were used to examine the...
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MP-LASSO chart: a multi-level polar chart for visualizing group LASSO analysis of genomic data

Song M, Lee M, Park T, Park M

Penalized regression has been widely used in genome-wide association studies for jointanalyses to find genetic associations. Among penalized regression models, the least absolute shrinkage and selection operator (Lasso) method effectively...
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A genetic approach to comprehend the complex and dynamic event of floral development: a review

Mohanty JN, Sahoo S, Mishra P

The concepts of phylogeny and floral genetics play a crucial role in understanding the origin and diversification of flowers in angiosperms. Angiosperms evolved a great diversity of ways to display...
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In silico detection and characterization of novel virulence proteins of the emerging poultry pathogen Gallibacterium anatis

Rajapaksha LGTG, Gunasekara CWR, Alwis PSD

The pathogen Gallibacterium anatis has caused heavy economic losses for commercial poultry farms around the world. However, despite its importance, the functions of its hypothetical proteins (HPs) have been poorly...
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Metagenomic analysis of viral genes integrated in whole genome sequencing data of Thai patients with Brugada syndrome

Chitcharoen S, Phokaew C, Mauleekoonphairoj J, Khongphatthanayothin A, Sutjaporn B, Wandee P, Poovorawan Y, Nademanee K, Payungporn S

Brugada syndrome (BS) is an autosomal dominant inheritance cardiac arrhythmia disorder associated with sudden death in young adults. Thailand has the highest prevalence of BS worldwide, and over 60% of...
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Development of reverse-transcription loop-mediated isothermal amplification assays for point-of-care testing of human influenza virus subtypes H1N1 and H3N2

Kang JS, Seo MR, Chung YJ

Influenza A virus (IAV) is the most widespread pathogen causing human respiratory infections. Although polymerase chain reaction (PCR)–based methods are currently the mostcommonly used tools for IAV detection, PCR is...
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Application of data fusion modeling for the prediction of auxin response elements in Zea mays for food security purposes

Sghaier N, Ayed RB, Rebai A

Food security will be affected by climate change worldwide, particularly in the developingworld, where the most important food products originate from plants. Plants are often exposed to environmental stresses that...
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The relationship of E-selectin singlenucleotide polymorphisms with breast cancer in Iraqi Arab women

Zakariya BF, Almohaidi AMS, Şimşek SA, Al-Waysi SA, Al-Dabbagh WH, Kamal AM

Breast cancer (BC) is a significant threat to female health, with both modifiable andnon-modifiable risk factors. It is essential to monitor patients regularly and to raise population awareness. Increasing research...
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