Genomics Inform.
2022 Dec;20(4):e39. 10.5808/gi.22074.
Overview of frequent pattern mining
- Affiliations
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- 1Laboratory of Statistical Genetics, Rockefeller University, New York, NY 10065, USA
- 2Department of Statistics, Seoul National University, Seoul 08826, Korea
- KMID: 2540167
- DOI: http://doi.org/10.5808/gi.22074
Abstract
- Various methods of frequent pattern mining have been applied to genetic problems, specifically, to the combined association of two genotypes (a genotype pattern, or diplotype) at different DNA variants with disease. These methods have the ability to come up with a selection of genotype patterns that are more common in affected than unaffected individuals, and the assessment of statistical significance for these selected patterns poses some unique problems, which are briefly outlined here.
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