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Editor's Introduction to This Issue

Chung YJ

No abstract available.
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SFannotation: A Simple and Fast Protein Function Annotation System

Yu DS, Kim BK

Owing to the generation of vast amounts of sequencing data by using cost-effective, high-throughput sequencing technologies with improved computational approaches, many putative proteins have been discovered after assembly and structural...
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Examining the Gm18 and m1G Modification Positions in tRNA Sequences

Subramanian M, Srinivasan T, Sudarsanam D

The tRNA structure contains conserved modifications that are responsible for its stability and are involved in the initiation and accuracy of the translation process. tRNA modification enzymes are prevalent in...
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New Lung Cancer Panel for High-Throughput Targeted Resequencing

Kim EH, Lee S, Park J, Lee K, Bhak J, Kim BC

We present a new next-generation sequencing-based method to identify somatic mutations of lung cancer. It is a comprehensive mutation profiling protocol to detect somatic mutations in 30 genes found frequently...
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Elucidating Molecular Interactions of Natural Inhibitors with HPV-16 E6 Oncoprotein through Docking Analysis

Kumar S, Jena L, Galande S, Daf S, Mohod K, Varma AK

Human papillomavirus (HPV) infection is the leading cause of cancer mortality among women worldwide. The life-threatening infection caused by HPV demands the need for designing anticancerous drugs. In the recent...
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Association Analysis of TEC Polymorphisms with Aspirin-Exacerbated Respiratory Disease in a Korean Population

Lee JS, Bae JS, Park BL, Cheong HS, Kim JH, Kim JY, Namgoong S, Kim JO, Park CS, Shin HD

The tyrosine-protein kinase Tec (TEC) is a member of non-receptor tyrosine kinases and has critical roles in cell signaling transmission, calcium mobilization, gene expression, and transformation. TEC is also involved...
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