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2DSpotDB: A Database for the Annotated Two-dimensional Polyacrylamide Gel Electrophoresis of Pathogen Proteins

Kim DW, Yoo WG, Lee MR, Kim YJ, Cho SH, Lee WJ, Ju JW

  • KMID: 2053277
  • Genomics Inform.
  • 2011 Dec;9(4):197-199.
The biological interpretation of two-dimensional (2D) gel electrophoresis experiments is a key step toward understanding the functions of biological systems. We here present a web-based integrated database, called 2DSpotDB, for...
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PromoterWizard: An Integrated Promoter Prediction Program Using Hybrid Methods

Park K, Kim KB

  • KMID: 2053276
  • Genomics Inform.
  • 2011 Dec;9(4):194-196.
Promoter prediction is a very important problem and is closely related to the main problems of bioinformatics such as the construction of gene regulatory networks and gene function annotation. In...
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SSR-Primer Generator: A Tool for Finding Simple Sequence Repeats and Designing SSR-Primers

Hong CP, Choi SR, Lim YP

  • KMID: 2053275
  • Genomics Inform.
  • 2011 Dec;9(4):189-193.
Simple sequence repeats (SSRs) are ubiquitous short tandem duplications found within eukaryotic genomes. Their length variability and abundance throughout the genome has led them to be widely used as molecular...
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How Many SNPs Should Be Used for the Human Phylogeny of Highly Related Ethnicities? A Case of Pan Asian 63 Ethnicities

Ghang H, Han Y, Jeong S, Bhak J, Lee S, Kim TH, Kim C, Kim S, Al-Mulla F, Youn CH, Yoo HS, The HUGO Pan-Asian SNP Consortium

  • KMID: 2053274
  • Genomics Inform.
  • 2011 Dec;9(4):181-188.
In planning a model-based phylogenic study for highly related ethnic data, the SNP marker number is an important factor to determine for relationship inferences. Genotype frequency data, utilizing a sub...
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Gene Expression Signatures for Compound Response in Cancers

He N, Yoon S

  • KMID: 2053273
  • Genomics Inform.
  • 2011 Dec;9(4):173-180.
Recent trends in generating multiple, large-scale datasets provide new challenges to manipulating the relationship of different types of components, such as gene expression and drug response data. Integrative analysis of...
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Gene Expression Analysis of Galpha13-/- Knockout Mouse Embryos Reveals Perturbations in Galpha13 Signaling Related to Angiogenesis and Hypoxia

Park JH, Choi S

  • KMID: 2053272
  • Genomics Inform.
  • 2011 Dec;9(4):161-172.
Angiogenesis is regulated by a large number of molecules and complex signaling mechanisms. The G protein Galpha13 is a part of this signaling mechanism as an endothelial cell movement regulator....
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Genome-wide Survey of Copy Number Variants Associated with Blood Pressure and Body Mass Index in a Korean Population

Moon S, Kim YJ, Kim YK, Kim DJ, Lee JY, Go MJ, Shin YA, Hong CB, Kim BJ

  • KMID: 2053271
  • Genomics Inform.
  • 2011 Dec;9(4):152-160.
Hypertension is the major factor of most death and high blood pressure (BP) can lead to stroke, myocardial infarction and cardiac failure. Moreover, hypertension is strongly correlated with body mass...
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Directed Causal Network Construction Using Linkage Analysis with Metabolic Syndrome-Related Expression Quantitative Traits

Kim KZ, Min JY, Kwon GY, Sung J, Cho SI

  • KMID: 2053270
  • Genomics Inform.
  • 2011 Dec;9(4):143-151.
In this study, we propose a novel, intuitive method of constructing an expression quantitative trait (eQT) network that is related to the metabolic syndrome using LOD scores and peak loci...
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