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A Bio-database Management System for the Monitoring and Automatic FTP of Public Databases

Tae H, Han JM, Ahn BY, Park K

  • KMID: 2166347
  • Genomics Inform.
  • 2008 Jun;6(2):95-97.
Many bioinformatics sites have managed local bio-databases, including major databases such as GenBank and PIR with update load. We have developed several programs to monitor the update status of these...
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The Korean HapMap Project Website

Kim YU, Kim SH, Jin H, Park YK, Ji M, Kim YJ

  • KMID: 2166346
  • Genomics Inform.
  • 2008 Jun;6(2):91-94.
Single nucleotide polymorphisms (SNPs) are the most abundant form of human genetic variation and are a resource for mapping complex genetic traits. A genome is covered by millions of these...
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An Optimized Strategy for Genome Assembly of Sanger/pyrosequencing Hybrid Data using Available Software

Jeong H, Kim JF

  • KMID: 2166345
  • Genomics Inform.
  • 2008 Jun;6(2):87-90.
During the last four years, the pyrosequencing-based 454 platform has rapidly displaced the traditional Sanger sequencing method due to its high throughput and cost effectiveness. Meanwhile, the Sanger sequencing methodology...
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In Vivo Target RNA Specificity of Trans-Splicing Phenomena by the Group I Intron

Song MS, Lee SW

  • KMID: 2166344
  • Genomics Inform.
  • 2008 Jun;6(2):84-86.
The Tetrahymena group I intron has been shown to employ a trans-splicing reaction and has been modified to specifically target and replace human telomerase reverse transcriptase (hTERT) RNA with a...
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Identification of Human LRG1 Polymorphisms and Their Genetic Association with Rheumatoid Arthritis

Jin EH, Chae SC, Shim SC, Kim HG, Chung HT

  • KMID: 2166343
  • Genomics Inform.
  • 2008 Jun;6(2):77-83.
Human leucine-rich alpha-2-glycoprotein 1 (LRG1 ) was first identified as a trace protein in human serum. The primary sequence of LRG1 includes repeated leucine residues and putative membrane-binding domains. But,...
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Functional Role of a Conserved Sequence Motif in the Oxygen-dependent Degradation Domain of Hypoxia-inducible Factor 1 alpha in the Recognition of p53

Chi SW

  • KMID: 2166342
  • Genomics Inform.
  • 2008 Jun;6(2):72-76.
Hypoxia-inducible factor 1 alpha (HIF1 alpha) is a transcription factor that plays a key role in the adaptation of cells to low oxygen stress and oxygen homeostasis. The oxygen-dependent degradation...
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J2dpathway: A Global Metabolic Pathway Viewer with Node-Abstracting Features

Song EH, Ham SI, Yang SD, Rhie A, Park HS, Lee SH

  • KMID: 2166341
  • Genomics Inform.
  • 2008 Jun;6(2):68-71.
The static approach of representing metabolic pathway diagrams offers no flexibility. Thus, many systems adopt automatic graph layout techniques to visualize the topological architecture of pathways. There are weaknesses, however,...
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KRDD: Korean Rice Ds-tagging Lines Database for Rice (Oryza sativa L. Dongjin)

Kim CK, Lee MC, Ahn BO, Yun DW, Yoon UH, Suh SC, Eun MY, Hahn JH

  • KMID: 2166340
  • Genomics Inform.
  • 2008 Jun;6(2):64-67.
The Korean Rice Ds-tagging lines Database (KRDD) is designed to provide information about Ac/Ds insertion lines and activation tagging lines using japonica rice. This database has provided information on 18,158...
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Development of KHapmap Browser using DAS for Korean HapMap Research

Jin H, Kim SH, Kim YU, Park YK, Ji M, Kim YJ

  • KMID: 2166339
  • Genomics Inform.
  • 2008 Jun;6(2):57-63.
The Korean HapMap Project has been carried out for the last 5 years since it started in June, 2003. The project generated data for a sum of 1,764,000 Korean SNPs...
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