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Unfolded Histidine-Tagged Protein is Immobilized to Nitrilotriacetic Acid-Nickel Beads, But Not the Nickel-Coated Glass Slide

Cho M, Ahn S, Park H

  • KMID: 1512149
  • Genomics Inform.
  • 2006 Sep;4(3):133-136.
The adsorption of proteins on the surface of glass slides is essential for construction of protein chips. Previously, we prepared a nickel-coated plate by the spin-coating method for immobilization of...
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GraPT: Genomic InteRpreter about Predictive Toxicology

Woo JH, Park YR, Jung Y, Kim JH, Kim JH

  • KMID: 1512148
  • Genomics Inform.
  • 2006 Sep;4(3):129-132.
Toxicogenomics has recently emerged in the field of toxicology and the DNA microarray technique has become common strategy for predictive toxicology which studies molecular mechanism caused by exposure of chemical...
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BioCC: An Openfree Hypertext Bio Community Cluster for Biology

Gong S, Kim TH, Oh J, Kwon J, Cho SA, Bolser D, Bhak J

  • KMID: 1512147
  • Genomics Inform.
  • 2006 Sep;4(3):125-128.
We present an openfree hypertext (also known as wiki) web cluster called BioCC. BioCC is a novel wiki farm that lets researchers create hundreds of biological web sites. The web...
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A Metabolic Pathway Drawing Algorithm for Reducing the Number of Edge Crossings

Song EH, Kim MK, Lee SH

  • KMID: 1512146
  • Genomics Inform.
  • 2006 Sep;4(3):118-124.
For the direct understanding of flow, pathway data are usually represented as directed graphs in biological journals and texts. Databases of metabolic pathways or signal transduction pathways inevitably contain these...
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Significant Gene Selection Using Integrated Microarray Data Set with Batch Effect

Kim KY, Chung HC, Jeung HC, Shin JH, Kim TS, Rha SY

  • KMID: 1512145
  • Genomics Inform.
  • 2006 Sep;4(3):110-117.
In microarray technology, many diverse experimental features can cause biases including RNA sources, microarray production or different platforms, diverse sample processing and various experiment protocols. These systematic effects cause a...
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Association of the Human IL-28RA Gene Polymorphisms in a Korean Population with Asthma

Chae SC, Park YR, Lee YC, Yang YS, Chung HT

  • KMID: 1512144
  • Genomics Inform.
  • 2006 Sep;4(3):103-109.
IL-28RA is one of the important candidate genes for complex trait of genetic diseases, but there are only a few published results for this gene. Previously, we identified eighteen SNPs...
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Identification of Gene Expression Signatures in Korean Acute Leukemia Patients

Lee KH, Park SW, Kim I, Yoon SS, Park S, Kim BK

  • KMID: 1512143
  • Genomics Inform.
  • 2006 Sep;4(3):97-102.
BACKGROUND: In acute leukemia patients, several successful methods of expression profiling have been used for various purposes, i.e., to identify new disease class, to select a therapeutic target, or to...
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