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D2GSNP: a web server for the selection of Single Nucleotide Polymorphisms within human disease genes

Kang HJ, Hong TH, Chung WH, Kim YU, Jung JH, Hwang SH, Han AR, Kim YJ

  • KMID: 2166194
  • Genomics Inform.
  • 2006 Mar;4(1):45-47.
D2GSNP is a web-based server for the selection of single nucleotide polymorph isms (SNPs) within genes related to human diseases. The D2GSNP is based on a relational database created by...
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XPERNATO-TOX: an Integrated Toxicogenomics Knowledgebase

Woo JH, Kim HE, Kong G, Kim JH

  • KMID: 2166193
  • Genomics Inform.
  • 2006 Mar;4(1):40-44.
Toxicogenomics combines transcriptome, proteome and metabolome profiling with conventional toxicology to investigate the interaction between biological molecules and toxicant or environmental stress in disease caution. Toxicogenomics faces the problems of...
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Deducing Isoform Abundance from Exon Junction Microarray

Kim PR, Oh SJ, Lee SH

  • KMID: 2166192
  • Genomics Inform.
  • 2006 Mar;4(1):33-39.
Alternative splicing (AS) is an important mechanism of producing transcriptome diversity and microarray techniques are being used increasingly to monitor the splice variants. There exist three types of microarrays interrogating...
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DNA Microarray Analysis of Gene Expression Profiles in Aging process of Mouse Brain

Lee MS, Heo JI, Kim JB, Park JB, Lee JY, Han JA, Kim JI

  • KMID: 2166191
  • Genomics Inform.
  • 2006 Mar;4(1):23-32.
In order to investigate the molecular basis of the aging process in brain, we have employed high-density oligonucleotide microarrays providing data on 10,108 gene clusters to define transcriptional patterns in...
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Gene Expression Profiling of 6-MP (6-mercaptopurine) in Liver

Kim HL, Kim HN, Lee EJ

  • KMID: 2166190
  • Genomics Inform.
  • 2006 Mar;4(1):16-22.
The KFDA (Korea Food & Drug Administration) has performed a collaborative toxicogenomics project since 2003. Its aim is to construct a toxicology database of 12 compounds administered to mice at...
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Identification of hRad21-Binding Sites in Human Chromosome

Chin C, Chung BS

  • KMID: 2166189
  • Genomics Inform.
  • 2006 Mar;4(1):11-15.
The aim of this study is to identify hRad21-binding sites in human chromosome, the core component of cohesin complex that held sister chromatids together. After chromatin immunoprecipitation with an hRad21...
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Cloning of Notl-linked DNA Detected by Restriction Landmark Genomic Scanning of Human Genome

Kim JH, Lee KT, Kim HC, Yang JO, Hahn YS, Kim SS, Kim SY, Yoo HS, Kim YS

  • KMID: 2166188
  • Genomics Inform.
  • 2006 Mar;4(1):1-10.
Epigenetic alterations are common features of human solid tumors, though global DNA methylation has been difficult to assess. Restriction Landmark Genomic Scanning (RLGS) is one of technology to examine epigenetic...
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