- XPERNATO-TOX: an Integrated Toxicogenomics Knowledgebase
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Woo JH, Kim HE, Kong G, Kim JH
- KMID: 2166193
- Genomics Inform.
- 2006 Mar;4(1):40-44.
Toxicogenomics combines transcriptome, proteome and metabolome profiling with conventional toxicology to investigate the interaction between biological molecules and toxicant or environmental stress in disease caution. Toxicogenomics faces the problems of... -
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- D2GSNP: a web server for the selection of Single Nucleotide Polymorphisms within human disease genes
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Kang HJ, Hong TH, Chung WH, Kim YU, Jung JH, Hwang SH, Han AR, Kim YJ
- KMID: 2166194
- Genomics Inform.
- 2006 Mar;4(1):45-47.
D2GSNP is a web-based server for the selection of single nucleotide polymorph isms (SNPs) within genes related to human diseases. The D2GSNP is based on a relational database created by... -
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- Identification of hRad21-Binding Sites in Human Chromosome
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Chin C, Chung BS
- KMID: 2166189
- Genomics Inform.
- 2006 Mar;4(1):11-15.
The aim of this study is to identify hRad21-binding sites in human chromosome, the core component of cohesin complex that held sister chromatids together. After chromatin immunoprecipitation with an hRad21... -
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- Cloning of Notl-linked DNA Detected by Restriction Landmark Genomic Scanning of Human Genome
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Kim JH, Lee KT, Kim HC, Yang JO, Hahn YS, Kim SS, Kim SY, Yoo HS, Kim YS
- KMID: 2166188
- Genomics Inform.
- 2006 Mar;4(1):1-10.
Epigenetic alterations are common features of human solid tumors, though global DNA methylation has been difficult to assess. Restriction Landmark Genomic Scanning (RLGS) is one of technology to examine epigenetic... -
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- Gene Expression Profiling of 6-MP (6-mercaptopurine) in Liver
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Kim HL, Kim HN, Lee EJ
- KMID: 2166190
- Genomics Inform.
- 2006 Mar;4(1):16-22.
The KFDA (Korea Food & Drug Administration) has performed a collaborative toxicogenomics project since 2003. Its aim is to construct a toxicology database of 12 compounds administered to mice at... -
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- DNA Microarray Analysis of Gene Expression Profiles in Aging process of Mouse Brain
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Lee MS, Heo JI, Kim JB, Park JB, Lee JY, Han JA, Kim JI
- KMID: 2166191
- Genomics Inform.
- 2006 Mar;4(1):23-32.
In order to investigate the molecular basis of the aging process in brain, we have employed high-density oligonucleotide microarrays providing data on 10,108 gene clusters to define transcriptional patterns in... -
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- Deducing Isoform Abundance from Exon Junction Microarray
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Kim PR, Oh SJ, Lee SH
- KMID: 2166192
- Genomics Inform.
- 2006 Mar;4(1):33-39.
Alternative splicing (AS) is an important mechanism of producing transcriptome diversity and microarray techniques are being used increasingly to monitor the splice variants. There exist three types of microarrays interrogating... -
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