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Improved Algorithms for the Identification of Yeast Proteins and Significant Transcription Factor and Motif Analysis

Lee SW, Hong SE, Lee KY, Choi DI, Chung HY, Hur CG

  • KMID: 2166220
  • Genomics Inform.
  • 2006 Jun;4(2):87-93.
With the rapid development of MS technologiesy, the demands for a more sophisticated MS interpretation algorithm haves grown as well. We have developed a new protein fingerprinting method using a...
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Construction of Chromosome-Specific BAC Libraries from the Filamentous Ascomycete Ashbya gossypii

Choi SD

  • KMID: 2166218
  • Genomics Inform.
  • 2006 Jun;4(2):80-86.
It is clear that the construction of large insert DNA libraries is important for map-based gene cloning, the assembly of physical maps, and simple screening for specific genomic sequences. The...
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Identification of Novel Genes with Proapoptotic Activity

Kang EJ, Kim JM, Kim NY, Park KM, Park SM, Kim NS, Yoo HS, Yeom YI, Kim SJ

  • KMID: 2166216
  • Genomics Inform.
  • 2006 Jun;4(2):77-79.
In order to identify novel proapoptotic genes, we screened approximately 1,000 hypothetical genes whose functions are completely unknown. After these genes were transiently expressed in HeLa cells, their nuclei images...
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Prediction of Exposure to 1763MHz Radiofrequency Radiation Using Support Vector Machine Algorithm in Jurkat Cell Model System

Huang TQ, Lee MS, Bae YJ, Park HS, Park WY, Sun SJ

  • KMID: 2166215
  • Genomics Inform.
  • 2006 Jun;4(2):71-76.
We have investigated biological responses to radiofrequency (RF) radiation in in vitro and in vivo models. By measuring the levels of heat shock proteins as well as the activation of...
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Theoretical Peptide Mass Distribution in the Non-Redundant Protein Database of the NCBI

Lim DJ, Oh HS, Kim HB

  • KMID: 2166213
  • Genomics Inform.
  • 2006 Jun;4(2):65-70.
Peptide mass mapping is the matching of experimentally generated peptides masses with the predicted masses of digested proteins contained in a database. To identify proteins by matching their constituent fragment...
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Single and Dual Ligand Effects on Gene Expression Changes in Mouse Macrophage Cells

Choi SD, Seo JS

  • KMID: 2166211
  • Genomics Inform.
  • 2006 Jun;4(2):57-64.
We identified differentially expressed genes in RAW264.7 cells in response to single and double ligand treatments (LPS, IFNgamma, 2MA, LPS plus IFNgamma, and LPS plus 2MA). The majority of the...
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Sample Size and Power Estimation in Case-Control Genetic Association Studies

Ahn C

  • KMID: 2166209
  • Genomics Inform.
  • 2006 Jun;4(2):51-56.
In planning a genetic association study, it is necessary to determine the number of samples to be collected for the study in order to achieve sufficient power to detect the...
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