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Challenges and New Approaches in Genomics and Bioinformatics

Park JH, Han KS

  • KMID: 1973989
  • Genomics Inform.
  • 2003 Sep;1(1):1-6.
No abstract available.
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Global Optimization of Clusters in Gene Expression Data of DNA Microarrays by Deterministic Annealing

Lee KM, Chung TS, Kim JH

  • KMID: 1973991
  • Genomics Inform.
  • 2003 Sep;1(1):20-24.
The analysis of DNA microarry data is one of the most important things for functional genomics research. The matrix representation of microarray data and its successive 'optimal' incisional hyperplanes is...
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Biological Network Evolution Hypothesis Applied to Protein Structural Interactome

Bolser DM, Park JH

  • KMID: 1973990
  • Genomics Inform.
  • 2003 Sep;1(1):7-19.
The latest measure of the relative evolutionary age of protein structure families was applied (based on taxonomic diversity) using the protein structural interactome map (PSIMAP). It confirms that, in general,...
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Computational Analysis of Neighboring Genes on Arabidopsis thaliana Chromosomes 4 and 5: Their Genomic Association as Functional Subunits

Goh SH, Kim TH, Kim JH, Nam DG, Choi D, Hur CG

  • KMID: 1973994
  • Genomics Inform.
  • 2003 Sep;1(1):40-49.
The genes related to specific events or pathways in bacteria are frequently localized proximate to the genome of their neighbors, as with the structures known as operon, but eukaryotic genes...
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Gene Expression Pattern Analysis via Latent Variable Models Coupled with Topographic Clustering

Chang JH, Chi SW, Zhang BT

  • KMID: 1973993
  • Genomics Inform.
  • 2003 Sep;1(1):32-39.
We present a latent variable model-based approach to the analysis of gene expression patterns, coupled with topographic clustering. Aspect model, a latent variable model for dyadic data, is applied to...
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A Heuristic Algorithm to Find All Normalized Local Alignments Above Threshold

Kim S, Sim JS, Park H, Park K, Park H, Seo JS

  • KMID: 1973992
  • Genomics Inform.
  • 2003 Sep;1(1):25-31.
Local alignment is an important task in molecular biology to see if two sequences contain regions that are similar. The most popular approach to local alignment is the use of...
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A Small Cryptic Plasmid pZMO1 of Zymomonas mobilis ATCC10988

Kang HL, Kang HS

  • KMID: 1973996
  • Genomics Inform.
  • 2003 Sep;1(1):55-60.
The nucleotide sequence of pZMO1, a small cryptic plasmid of Zymomonas mobilis ATCC10988 was determined. Analysis of 1,680 bp of sequence revealed 69% identity with Shigella sonnei plasmid, pKYM and...
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Genome Mapping of an Extreme Thermophile, Thermus caldophilus GK24

Park JH, Park BC, Koch SH, Kim JS, Koh JH, Yang MH, Kim YS, Kim CH, Kim MH, Kwon ST, Lee DS

  • KMID: 1973995
  • Genomics Inform.
  • 2003 Sep;1(1):50-54.
Genome of an extreme thermophile, Thermus caldophilus GK24 has been analyzed to construct the genomic map. The genomic DNAs encapsulated in agarose gel were digested with SspI, EcoRI, SpeI, and...
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