- Heritability and linkage study on heart rates in a Mongolian population
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Gombojav B, Park H, Kim JI, Ju YS, Sung J, Cho SI, Lee MK, Ohrr H, Radnaabazar J, Seo JS
- KMID: 1104810
- Exp Mol Med.
- 2008 Oct;40(5):558-564.
- doi: 10.3858/emm.2008.40.5.558
Elevated heart rate has been proposed as an independent risk factor for cardiovascular diseases, but their interrelationships are not well understood. In this study, we performed a genome-wide linkage scan... -
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- Identification of novel substrates for human checkpoint kinase Chk1 and Chk2 through genome-wide screening using a consensus Chk phosphorylation motif
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Kim MA, Kim HJ, Brown AL, Lee MY, Bae YS, Park JI, Kwak JY, Chung JH, Yun J
- KMID: 1094661
- Exp Mol Med.
- 2007 Apr;39(2):205-212.
Checkpoint kinase 1 (Chk1) and Chk2 are effector kinases in the cellular DNA damage response and impairment of their function is closely related to tumorigenesis. Previous studies revealed several substrate... -
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- Integrative epigenomic and genomic analysis of malignant pheochromocytoma
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Sandgren J, Andersson , Rada-Iglesias A, Enroth S, Akerstrom , Dumanski J, Komorowski J, Westin G, Wadelius C
- KMID: 1104209
- Exp Mol Med.
- 2010 Jul;42(7):484-502.
- doi: 10.3858/emm.2010.42.7.050
Epigenomic and genomic changes affect gene expression and contribute to tumor development. The histone modifications trimethylated histone H3 lysine 4 (H3K4me3) and lysine 27 (H3K27me3) are epigenetic regulators associated to... -
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