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Clinicopathological Features of Rare BRAF Mutations in Korean Thyroid Cancer Patients

Cho U, Oh WJ, Bae JS, Lee S, Lee YS, Park GS, Lee YS, Jung CK

The most common BRAF mutation in thyroid cancer is c.1799T>A (p.Val600Glu), and other BRAF mutations are rarely reported. We investigated the clinicopathological features of thyroid cancer with rare BRAF mutations....
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KISS1 Gene Polymorphisms in Korean Girls with Central Precocious Puberty

Rhie YJ, Lee KH, Ko JM, Lee WJ, Kim JH, Kim HS

Kisspeptin/G-protein couple receptor-54 (GPR54) system plays a key role in the activation of the gonadotropic axis at puberty. Central precocious puberty (CPP) is caused by the premature activation of hypothalamic...
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Gender-Specific Associations between CHGB Genetic Variants and Schizophrenia in a Korean Population

Shin JG, Kim JH, Park CS, Kim BJ, Kim JW, Choi IG, Hwang J, Shin HD, Woo SI

PURPOSE: Schizophrenia is a devastating mental disorder and is known to be affected by genetic factors. The chromogranin B (CHGB), a member of the chromogranin gene family, has been proposed...
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Prognostic role of genetic biomarkers in clinical progression of prostate cancer

Alvarez-Cubero MJ, Martinez-Gonzalez LJ, Saiz M, Carmona-Saez P, Alvarez JC, Pascual-Geler M, Lorente JA, Cozar JM

The aim of this study was to analyze the use of 12 single-nucleotide polymorphisms in genes ELAC2, RNASEL and MSR1 as biomarkers for prostate cancer (PCa) detection and progression, as...
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Candidate gene polymorphisms for diabetes mellitus, cardiovascular disease and cancer are associated with longevity in Koreans

Park JW, Ji YI, Choi YH, Kang MY, Jung E, Cho SY, Cho HY, Kang BK, Joung YS, Kim DH, Park SC, Park J

Long-lived people may have a unique genetic makeup that makes them more resistant than the general population to prevalent age-related diseases; however, not much is known about genes involved in...
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Molecular Identification of Haemadipsa rjukjuana (Hirudiniformes: Haemadipsidae) in Gageo Island, Korea

Won S, Park BK, Kim BJ, Kim HW, Kang JG, Park TS, Seo HY, Eun Y, Kim KG, Chae JS

  • KMID: 1792164
  • Korean J Parasitol.
  • 2014 Apr;52(2):169-175.
There are 60 species of blood-feeding land leeches, 50 species belonging to the family Haemadipsidae and 10 species belonging to the family Xerobdellidae. Despite recent papers on the land leeches,...
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Association between Promoter Polymorphisms of TFF1, TFF2, and TFF3 and the Risk of Gastric and Diffuse Gastric Cancers in a Korean Population

Jin EH, Lee SI, Kim J, Seo EY, Lee SY, Hur GM, Shin S, Hong JH

Gastric cancer is one of the most common cancers in the world. The aims of this study were to evaluate the association between polymorphisms in TFF gene family, TFF1, TFF2,...
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Overexpression of SOX9 in mouse embryonic stem cells directs the immediate chondrogenic commitment

Kim JH, Do HJ, Yang HM, Oh JH, Choi SJ, Kim DK, Cha KY, Chung HM

  • KMID: 1093460
  • Exp Mol Med.
  • 2005 Aug;37(4):261-268.
Mouse embryonic stem (mES) cells are capable of undergoing chondrogenesis in vitro. To enhance this process, the human SOX9 (hSOX9) cDNA was delivered into mES cells and the clones overexpressing...
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Potential biomarkers as an indicator of vertical transmission of Johne's disease in a Korean native cattle farm

Park HT, Park HE, Cho YI, Kim EH, Jung M, Shin SW, Lee SH, Kim DY, Yoo HS

Paratuberculosis (PTB) is caused by Mycobacterium avium subsp. paratuberculosis (MAP) and is one of the most widespread and economically important diseases in cattle. After birth, calves are raised with natural...
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HLA Antigens in Malay Patients with Systemic Lupus Erythematosus: Association with Clinical and Autoantibody Expression

Azizah MR, Ainol SS, Kong N, Normaznah , Rahim MN

  • KMID: 938278
  • Korean J Intern Med.
  • 2001 Jun;16(2):123-131.
BACKGROUND: Studies have shown that certain genes within the major histocompatibility complex predispose to systemic lupus erythematosus (SLE) and may influence clinical and autoantibody expression. Thus, we studied the frequency...
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