- Mutations of p53 Tumor Suppressor Gene in Spontaneous Canine Mammary Tumors
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Lee CH, Kweon OK
- KMID: 1097349
- J Vet Sci.
- 2002 Dec;3(4):321-325.
Mutation of the p53 tumor suppressor gene has been related in the pathogenesis of numerous human and canine cancers, including breast cancers and mammary tumors. We have investigated exons 5-8... -
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- p53 protein overexpression and allele loss of p53 gene in gastric adenocarcinoma
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Choi SW, Park WS, Yang JM, Kang CS, Sun HS, Kim BS, Seo EJ, Lee MJ, Park CS
- KMID: 644812
- J Korean Med Sci.
- 1994 Aug;9(4):299-303.
- doi: 10.3346/jkms.1994.9.4.299
Gene alterations of p53 tumor suppressor gene such as point mutations, deletions or insertions occur in various human cancers. p53 protein overexpression was studied immunohistochemically in 80 gastric adenocarcinomas using... -
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- p53 Genetic Polymorphism of Gastric cancer in Korea
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Chung WC, Lee KM, Lee BI, Chun JS, Lee SY, Chang UI, Park SH, Yang JM, Choi KY, Chung IS
- KMID: 1782248
- Korean J Intern Med.
- 2006 Mar;21(1):28-32.
- doi: 10.3904/kjim.2006.21.1.28
BACKGROUND: Deletion or functional loss of the p53 tumor suppression gene plays a role in oncogenic transformation. The codon 72 polymorphism on exon 4 in the p53 gene produces... -
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- Mutation and overexpression of p53 as a prognostic factor in canine mammary tumors
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Lee CH, Kim WH, Lim JH, Kang MS, Kim DY, Kweon OK
- KMID: 1094689
- J Vet Sci.
- 2004 Mar;5(1):63-69.
We concentrated ourselves to evaluate the prognostic significance of the p53 gene mutations, its protein expression and MIB-1 index as a proliferative marker in canine mammary tumors. In the present... -
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