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Oncogene interaction in basal cell carcinomas of human skin

Ro YS

The expression of the p53 protein (p53) was compared with those of several oncogenes including c-fos (Fos), c-jun (Jun), and epidermal growth factor receptor (EGFR1) using immunohistochemistry in frozen and...
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Expression of Fos Protein in Brainstem Vestibular Nuclei of Rat - I. Off-axis Centripetal Acceleration -

Suh HK, Park HJ, Lim HH, Hwang SJ

  • KMID: 2274305
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 Feb;40(2):286-291.
Fos, the protein product of c-fos gene, has been known to be rapidly expressed in neurons following various external and internal stimuli. This experiment was performed to determine whether off-axis...
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Expressions of c-fos and c-myc genes during 3'-methyl-4-dimethylaminoazobenzene (3'-MeDAB)-induced rat hepatocarcinoma

Chai KJ, Kim JS, Lee HK

We investigated the expression of the growth-related nuclear proto-oncogenes, c-fos and c-myc, in early preneoplastic regions and tumor nodules of 3'-MeDAB induced rat hepatocarcinoma. To amplify the levels of these...
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Expression of Fos Protein in Brainstem Vestibular Nuclei of Rat-II. Sinusoidal Acceleration Stimulation-

Suh HK, Woo JS, Park HJ, Yoo DH, Lee ES, Lim HH, Hwang SJ

  • KMID: 2274516
  • Korean J Otolaryngol-Head Neck Surg.
  • 1998 Dec;41(12):1513-1520.
BACKGROUND AND OBJECTIVES: Fos, the protein product of c-fos gene, has been known to be rapidly expressed in neurons following various external and internal stimuli and this protein expression has...
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Immunohistochemical Detection of p53 and c-fos in Brain Gliomas

Son EI, Lee CC, Kim DW, Yim MB, Kim IH, Lee SS

  • KMID: 1954700
  • J Korean Neurosurg Soc.
  • 1994 Apr;23(4):402-407.
The epidemiology of cancer has long been suggested that cancer is multistep disease. We suspect some of these steps might be lated with activation of oncogenes and loss of tumor...
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Effect of Protein Kinase C Inhibitor (PKCI) on Radiation Sensitivity and c-fos Transcription Activity

Choi EK, Chang H, Rhee YH, Park KK

  • KMID: 1557157
  • J Korean Soc Ther Radiol Oncol.
  • 1999 Dec;17(4):299-306.
PURPOSE: The human genetic disorder ataxia-telangiectasia (AT) is a multisystem disease characterized by extreme radiosensitivity. The recent identification of the gene mutated in AT, ATM, and the demonstration that it...
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The Signaling Pathway of G-protein Rac and Eicosanoid Synthesis by Titanium Particles

Lee SS, Her JY, Woo CH, Kim JH, Chang JD

  • KMID: 2105760
  • J Korean Orthop Assoc.
  • 2001 Aug;36(4):317-325.
PURPOSE: In order to understand the intracellular signaling pathway involving the c-fos gene expression that is caused by Titanium-particles, we analyzed the involvement of Rac, cytosolic phospholipase A2, and eicosanoids...
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Comparison of Fos Protein Expressions Rat Hippocampus Following Single and Repeated Intraperitoneal Administration of Kainic Acid

Kim KS, Yoo KM, Chang HK

  • KMID: 1539060
  • J Korean Epilepsy Soc.
  • 1999 Jun;3(1):33-38.
BACKGROUND:Acute seizures that increase neuronal activity cause a rapid and transient induction of the immmediate early c-fos in specific brain regions. C-fos gene may mediate long-term changes in cell function,...
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The Changes of c-fos and c-jun after Capsaicine Treatment in the Rat Brain

Park GA, Lee JE, Park SH, Jang SH, Lee WT

  • KMID: 2224616
  • Korean J Anat.
  • 1997 Aug;30(4):351-360.
The expression of c-fos and c-jun in the brain of the rat after capsaicin treatment was investigated by in situ hybridization, dot blot hybridization and immunocytochemical methods. Adult male Sprague-Dawley...
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The Subdivision of the Spinal Neurons for Detrusor Function

Jeon HJ, Lee HY, Noh JY, Hong CH, Kim JH, Han SW

  • KMID: 2293972
  • Korean J Urol.
  • 2005 May;46(5):487-494.
Purpose: No ideal method for subdividing and assessing changes in neurons of the spinal cord during specific conditions has been established. We attempted to develop a method for subdividing spinal...
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Gene expression profiling of light-induced retinal degeneration in phototransduction gene knockout mice

Krishnan J, Chen J, Shin KJ, Hwang JI, Han SU, Lee G, Choi S

Exposure to light can induce photoreceptor cell death and exacerbate retinal degeneration. In this study, mice with genetic knockout of several genes, including rhodopsin kinase (Rhok-/-), arrestin (Sag-/-), transducin (Gnat1-/-),...
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The Effect and Mechanism of Intravesical Electrical Stimulation in Spinal Cord Injured Rats

Jeon HJ, Jin MH, Ko HK, Hong CH, Kim JH, Han SW

PURPOSE: The objective of this study was to evaluate whether the effect on afferent c-fiber activity is the underlying mechanism of intravesical electrical stimulation (IVES) in spinal cord injured rats. MATERIALS...
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Role of the Peripheral Vestibular System on Neuroplasticity Induced by Hypergravity Stimulation

Lee JH, Lee GW, Park HS, Lee JH, Choi DO, Choi MA, Park BR

  • KMID: 1603943
  • J Korean Bal Soc.
  • 2006 Dec;5(2):213-223.
BACKGROUND AND OBJECTIVES: Altered environmental gravity, including both hypo- and hypergravity, may result in space adaptation syndrome. To explore the characteristics of this adaptive plasticity, the expression of immediate early...
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The effects of superoxide dismutase on the expression of c-fos gene in the chronic post-ischemic pain model rats

Kim TK, Shin SW, Jung H, Lim DG

BACKGROUND: Chronic post-ischemia pain (CPIP) model is reported to represent the complex regional pain syndrome type I. The administration of non-specific free radical scavengers reduced mechanical allodynia, but it is...
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Expression of the c-myc and c-fos Protooncogenes in Human Thyroid Tumors

Moon BI, Kim CW, Youn YK, Oh SK

  • KMID: 2206231
  • J Korean Surg Soc.
  • 1997 Jun;52(6):804-823.
Some proto-oncogenes in human malignancies can be primary cause of carcinogenesis and can be correlated to histologic aggressiveness or prognosis. In this study, to define the role of c-myc and...
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Dexamethasone-induced differentiation of pancreatic AR42J cell involves p21(waf1/cip1)and MAP kinase pathway

Eum WS, Li MZ, Sin GS, Choi SY, Park JB, Lee JY, Kwon HY

  • KMID: 1093610
  • Exp Mol Med.
  • 2003 Oct;35(5):379-384.
Dexamethasone converts pluripotent pancreatic AR42J cells into exocrine cells expressing digestive enzymes. In order to address molecular mechanism of this differentiation, we have investigated the role of mitogen-activated protein (MAP)...
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Association Study of FOS-Like Antigen-2 Promoter Polymorphisms With Papillary Thyroid Cancer in Korean Population

Kim SW, Kim CD, Chung JH, Kwon KH

  • KMID: 2278403
  • Clin Exp Otorhinolaryngol.
  • 2014 Mar;7(1):42-46.
OBJECTIVES: FOS-like antigen-2 (FOSL-2), a member of the FOS gene family, encode leucine zipper proteins that can heterodimerize with proteins of Jun family. Thus, activating protein (AP)-1 transcription factor is...
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Characteristics of Lithium-Pilocarpine Seizure Model: Behaviors, Electroencephalography, Fos Expression and Neuropathologic changes

Kim YI, Lee KS, Kim BS, Kim YJ, Chun MH, Kim MS

  • KMID: 2066046
  • J Korean Neurol Assoc.
  • 1996 Mar;14(1):74-88.
It is well known that the status epilepticus induced by the administration of pilocarpine to lithium-pretreated rats is a role model to study for the cholinergic system in epileptogenesis and...
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Gene expression pattern during osteogenic differentiation of human periodontal ligament cells in vitro

Choi MH, Noh WC, Park JW, Lee JM, Suh JY

PURPOSE: Periodontal ligament (PDL) cell differentiation into osteoblasts is important in bone formation. Bone formation is a complex biological process and involves several tightly regulated gene expression patterns of bone-related...
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Effect of peripheral nerve stimulation on the dorsal horn cell activity in cats with cutaneous inflammation

Nam TS, Song SH, Kim YH, Baik EJ, Paik KS

There are some reports showing that an experience of long-enduring pain causes a change in the pain transmission system, suggesting a plastic nature of the nociceptive system. However, most of...
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