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Cyclin D1 Gene Amplification in Oral Squamous Cell Carcinoma using Differential Polymerase Chain Reaction

Kim KS, Kim KW, Lee JH, Kim CJ

  • KMID: 2005998
  • J Korean Assoc Oral Maxillofac Surg.
  • 2000 Aug;26(4):355-362.
Neoplastic growth is characterized by alterations of oncogenes and antioncogenes. The interaction between activated oncogenes and functional deletion of antioncogene appears to be the driving force directing normal cells to...
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Expression of beta-Catenin, c-Myc, and Cyclin D1 in Pulmonary Adenocarcinomas

Chun BK, Yoon HK

  • KMID: 2275588
  • Korean J Pathol.
  • 2001 Dec;35(6):486-495.
BACKGROUND: beta-Catenin has dual functions: adhesive molucule and transcriptional activator. Subcellular accumulation of beta-catenin and subsequent formation of beta-catenin- Tcf/Lef-1 complexes, as well as c-myc and cyclin D1 genes...
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Amplification and Overexpression of Cyclin D1 in Head and Neck Squamous Cell Carcinomas

Kim SH, Yeom BW

  • KMID: 1920908
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 Dec;40(12):1801-1807.
BACKGROUND: Overexpression of the cell cycle control gene, cyclin D1 may, at least in some tumor types, provide a prognostic marker. Cyclin D1 is expressed during the G1 phase of...
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Longer Survival in Patients with Breast Cancer with Cyclin D1 Over-Expression after Tumor Recurrence: Longer, but Occupied with Disease

Chung J, Noh H, Park KH, Choi E, Han A

  • KMID: 2353083
  • J Breast Cancer.
  • 2014 Mar;17(1):47-53.
PURPOSE: The effect of cyclin D1 overexpression on breast cancer outcomes and prognosis is controversial, even though amplification of the cyclin D1 gene, CCND1, has been shown to be associated...
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Human Papillomavirus Infection and Expression of Cyclin D1 in the Uterine Cervical Neoplasia

Kim MK, Kim HB, Lee SK, Sunwoo JG, Bae DH, Kim CJ

  • KMID: 2143478
  • Korean J Gynecol Oncol Colposc.
  • 2002 Mar;13(1):28-37.
About 80 subtypes of human papilloma viruses(HPVs) were known, and they were divided into two groups as 'high-risk HPVs' and 'low-risk HPVs' according to their oncogenic potentialities. Even though the...
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Cyclin D1 Expression in Primary Breast Carcinoma: Correlation with Estrogen Receptor Status and Other Clinicopathologic Parameters

Seo HC, Kim SI, Yang WI, Park CH, Park CJ

PURPOSE: Cyclins are groups of proteins that play a role as a major regulator of the G1 restriction point promoting inactivation of the retinoblastoma protein. The cyclin D1 gene, CCND1,...
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Cyclin D1 Expression in Primary Breast Carcinoma: Correlation with Estrogen Receptor Status and Other Clinicopathologic Parameters

Seo HC, Kim SI, Yang WI, Park CH, Park CJ

  • KMID: 2324959
  • J Korean Surg Soc.
  • 2001 Nov;61(5):479-484.
PURPOSE: Cyclins are groups of proteins that play a role as a major regulator of the G1 restriction point promoting inactivation of the retinoblastoma protein. The cyclin D1 gene, CCND1,...
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Detection of IgH and Cyclin D1 gene Rearrangement with Interphase FISH in Multiple Myeloma

Huh JW, Ahn JY, Lee JH, Im SA, Seong CM, Chung WS

  • KMID: 2082779
  • Korean J Lab Med.
  • 2002 Oct;22(5):367-371.
BACKGROUND: The t(11;14)(q13;q32) is known to be one of the most frequent chromosomal abnor-malities found in multiple myeloma (MM). However, studies on t(11;14) in MM have been problemat-ic due to...
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Prognostic Significance of Cyclin D1 Overexpression in Non-Small Cell Lung Cancer

Yang SC, Shin DH, Park SS, Lee JH, Keum JS, Kong G, Lee JD

BACKGROUND: The cyclin D1 gene is one of the most frequently amplified chromosomal regions(11ql3) in human carcinomas. In laryngeal and head and neck carcinomas, its overexpression has been shown to...
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