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Role of the nm23-H1 gene in the metastasis of gastric cancer

Hwang BG, Park IC, Park MJ, Moon NM, Choi DW, Hong WS, Lee SH, Hong SI

The nm23 gene is now generally accepted as one of the suppressor genes for metastasis in many types of human cancer. To investigate the role of the nm23 gene...
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Loss of heterozygosity on chromosome XP22.2-p22.13 and Xq26.1-q27.1 in human breast carcinomas

Choi C, Kim MH, Juhng SW

In an attempt to investigate the X chromosome harboring putative tumor suppressor genes (TSGs) in sporadic breast carcinoma, we performed loss of heterozygosity (LOH) studies on 23 breast carcinomas...
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Administration of multiple cytokine genes with anti-tumor activity inhibits both tumor incidence and tumor growth

Jang HS, Cho TH, Jang YS, Choung PH

The finding of reporter gene expression in muscle cells after intramuscular injection of a reporter gene containing DNA has suggested that injection of a certain gene in its...
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TGF-beta1 inhibition of apoptosis through the transcriptional up-regulation of Bcl-X(L) in human monocytic leukemia U937 cells

Lee JH, Park BJ, Park JH, Yang MH, Chi SG

  • KMID: 755040
  • Exp Mol Med.
  • 1999 Sep;31(3):126-133.
To characterize the TGF-beta1 response of monocytic leukemia cells, we analyzed the effects of TGF-beta1 on cell proliferation, differentiation, and apoptosis of human monoblastic U937 cells. Treatment of cells with TGF-beta1 in...
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