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In vivo determination of the gap2 gene promoter activity in Giardia lamblia

Yang HW, Kim J, Yong TS, Park SJ

A shuttle vector for Escherichia coli and Giardia lamblia was modified to produce a reporter plasmid, which monitors the expression of prescribed gene in G. lamblia by measuring its luciferase...
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p53 overexpression represses androgen-mediated induction of NKX3.1 in a prostate cancer cell line

Jiang A, Yu C, Zhang P, Chen W, Liu W, Hu X, Zhang J

  • KMID: 1115940
  • Exp Mol Med.
  • 2006 Dec;38(6):625-633.
Prostate cancer is a disease involving complicated multiple-gene alterations. Both NKX3.1 and p53 are related to prostate cancer and play crucial roles in prostate cancer progression. However, little is known...
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Weakening of the repressive YY-1 site on the thrombospondin-1 promoter via c-Jun/YY-1 interaction

Kang JH, Chang SY, Yeom DH, Kim SA, Um SH, Hong KJ

  • KMID: 1094074
  • Exp Mol Med.
  • 2004 Aug;36(4):300-310.
Thrombospondin-1 (TSP-1) level is tightly regulated at the transcriptional level. To determine the detailed molecular mechanisms of TSP-1 expression, nine serial 5'-deletion constructs of the human genomic tsp-1 promoter (nucleotides...
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Cardiac expression profiles of the naked DNA vectors encoding vascular endothelial growth factor and basic fibroblast growth factor

Lee JS, Byun J, Kim JM, Kim CY, Kim BM, Chung JH, Jang Y, Kim DK

  • KMID: 1089454
  • Exp Mol Med.
  • 2005 Oct;37(5):447-456.
We investigated expression profiles and biological effects of the naked DNA vectors in the heart. To this end, naked DNA vector was injected into the apex of the beating rat...
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