- HIV-1 Tat Protein Promotes Amyloid beta Generation and Tau Phosphorylation in Rat Hippocampal Slices
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Lee EO, Jhang KA, An YW, Ju W, Chong YH
- KMID: 2135363
- J Bacteriol Virol.
- 2014 Mar;44(1):102-107.
- doi: 10.4167/jbv.2014.44.1.102
HIV-1 Tat protein has been implicated as a causative agent in the pathogenesis of HIV-1-associated neurocognitive disorder (HAND) and Alzheimer's disease (AD)-like pathology in HIV-1 infected patients. Here, we provide... -
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- HIV-1 Tat Protein-dependent Cytotoxicity is Attenated by 15-deoxy-Delta12,14-Prostaglandin J2 in Rat Hippocampal Slices: Involvement of the ERK1/2 Signaling Pathway
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Lee EO, Yang JH, Kim JH, Woo SY, Chong YH
- KMID: 1782702
- J Bacteriol Virol.
- 2013 Mar;43(1):45-53.
- doi: 10.4167/jbv.2013.43.1.45
15-deoxy-delta12,14 prostaglandin J2 (15d-PGJ2) may hold promise in treatment of the pathologies associated with human immunodeficiency virus (HIV) infection of the central nervous system. However, its precise role and neuroprotective... -
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- HIV-1 Infection Causes Intracellular Expression of p53, Which Induces PKR Expression, Followed by Inhibition of HIV-1 Tat Activity
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Yoon CH, Woo JY, Bae YS
- KMID: 2055008
- J Bacteriol Virol.
- 2004 Jun;34(2):157-166.
Few papers have reported that the HIV-1 replication was inhibited by p53 in the infected cells. However, the detail mechanism for the p53-medicated HIV-1 suppression has not yet been clearly... -
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- Extracellular HIV-1 Tat enhances monocyte adhesion by up-regulation of ICAM-1 and VCAM-1 gene expression via ROS-dependent NF-kappaB activation in astrocytes
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Song HY, Ryu J, Ju SM, Park LJ, Lee JA, Choi SY, Park J
- KMID: 1103678
- Exp Mol Med.
- 2007 Feb;39(1):27-37.
One of characteristic features of AIDS-related encephalitis and dementia is the infiltration of monocytes into the CNS. HIV-1 Tat was demonstrated to facilitate monocyte entry into the CNS. In this... -
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- Suppression of HIV-1 Tat-induced monocyte adhesiveness by a cell-permeable superoxide dismutase in astrocytes
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Song HY, Ju SM, Lee JA, Kwon HJ, Eum WS, Jang SH, Choi SY, Park J
- KMID: 1091072
- Exp Mol Med.
- 2007 Dec;39(6):778-786.
HIV-1 Tat is considered to be one of key players to facilitate monocyte entry into the CNS, which is characteristic feature of AIDS-related encephalitis and dementia. This study was performed... -
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- Bone regenerative effects of recombinant human bone morphogenetic protein-2 employed protein transduction domain
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Jung SW, Kim NH, Yook JI, Kim CS, Kim HJ, Cho KS
- KMID: 2191717
- J Korean Acad Periodontol.
- 2007 Sep;37(3):497-509.
- doi: 10.5051/jkape.2007.37.3.497
Bone morphogenetic proteins(BMPs) are regarded as members of the transforming growth factor-beta superfamily with characteristic features in their amino acid sequences. A number of studies have demonstrated the biologic activities... -
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- Transduction of yeast cytosine deaminase mediated by HIV-1 Tat basic domain into tumor cells induces chemosensitivity to 5-fluorocytosine
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Lee H, Ryu J, Kim KA, Lee KS, Lee JY, Park JB, Park J, Choi SY
- KMID: 755664
- Exp Mol Med.
- 2004 Feb;36(1):43-51.
Enzyme/prodrug approach is one of the actively developing areas for cancer therapy. In an effort to develop more effective enzyme/prodrug systems, cell-permeable cytosine deaminase was produced by fusing yeast cytosine... -
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- Labeling Efficacy of Superparamagnetic Iron Oxide Nanoparticles to Human Neural Stem Cells: Comparison of Ferumoxides, Monocrystalline Iron Oxide, Cross-linked Iron Oxide (CLIO)-NH2 and tat-CLIO
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Song M, Moon WK, Kim Y, Lim D, Song IC, Yoon BW
- KMID: 1734284
- Korean J Radiol.
- 2007 Oct;8(5):365-371.
- doi: 10.3348/kjr.2007.8.5.365
OBJECTIVE: We wanted to compare the human neural stem cell (hNSC) labeling efficacy of different superparamagnetic iron oxide nanoparticles (SPIONs), namely, ferumoxides, monocrystalline iron oxide (MION), cross-linked iron oxide (CLIO)-NH2... -
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