- Identification and characterization of scirr1, a novel gene up-regulated after spinal cord injury
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Liu T, Ma Z, Que H, Li X, Ni Y, Jing S, Liu S
- KMID: 1047076
- Exp Mol Med.
- 2007 Jun;39(3):255-266.
Spinal cord injury and regeneration involves transcriptional activity of many genes, of which many remain unknown. Using the rat spinal cord full- transection model, bioinformatics, cloning, expression assays, fusion proteins,... -
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- Molecular cloning of clathrin assembly protein gene (rCALM) and its differential expression to AP180 in rat brain
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Kim HL, Lee SC
- KMID: 1029926
- Exp Mol Med.
- 1999 Dec;31(4):191-196.
Binding of clathrin assembly protein to clathrin triskelia induces their assembly into clathrin-coated vesicle (CCV) in neurons. The clathrin assembly protein gene (rCALM) was cloned from rat brain... -
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- Transcriptional regulation of Zic3 by heterodimeric AP-1(c-Jun/c-Fos) during Xenopus development
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Lee SY, Lee HS, Moon JS, Kim JI, Park JB, Lee JY, Park MJ, Kim J
- KMID: 1123768
- Exp Mol Med.
- 2004 Oct;36(5):468-475.
The heterodimeric c-Jun/c-Fos, an activator protein-1 (AP-1) has been implicated in mesoderm induction (Dong et al., 1996; Kim et al., 1998) whereas the homodimer of c-Jun was reported to be... -
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- Polycystin-1 Expression in Fetal, Adult and Autosomal Dominant Polycystic Kidney
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Chae SW, Cho EY, Park MS, Lee KB, Kim H, Kim U
- KMID: 1778422
- J Korean Med Sci.
- 2006 Jun;21(3):425-429.
- doi: 10.3346/jkms.2006.21.3.425
The mutation of the PKD1 gene causes autosomal dominant polycystic kidney disease (ADPKD), and the PKD1 gene encodes polycystin-1 (PC-1). PC-1 is thought to be a cell-cell/matrix adhesion receptor molecule... -
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- A simplified one-step nuclear transfer procedure alters the gene expression patterns and developmental potential of cloned porcine embryos
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Park SK, Roh S, Park JI
- KMID: 1737612
- J Vet Sci.
- 2014 Mar;15(1):73-80.
- doi: 10.4142/jvs.2014.15.1.73
Various somatic cell nuclear transfer (SCNT) techniques for mammalian species have been developed to adjust species-specific procedures to oocyte-associated differences among species. Species-specific SCNT protocols may result in different expression... -
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- Nuclear receptor regulation of stemness and stem cell differentiation
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Jeong Y, Mangelsdorf DJ
- KMID: 1119318
- Exp Mol Med.
- 2009 Aug;41(8):525-537.
- doi: 10.3858/emm.2009.41.8.091
Stem cells include a diverse number of toti-, pluri-, and multi-potent cells that play important roles in cellular genesis and differentiation, tissue development, and organogenesis. Genetic regulation involving various transcription... -
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- A Novel 1.13 Mb Interstitial Duplication at 19q13.32 Causing Developmental Delay and Microcephaly in a Pediatric Patient: the First Asian Case Report
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Rim JH, Kim JA, Yoo J
- KMID: 2418909
- Yonsei Med J.
- 2017 Nov;58(6):1241-1244.
- doi: 10.3349/ymj.2017.58.6.1241
Only 6 patients with partial trisomy of the long arm of chromosome 19 (19q), caused by direct interstitial duplications, have been reported until today. Herein, we report a pediatric patient... -
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- Expression of KA1 kainate receptor subunit in the substantia gelatinosa of the trigeminal subnucleus caudalis in mice
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Park SA, Park SJ, Han SK
- KMID: 1072178
- J Vet Sci.
- 2010 Dec;11(4):299-304.
- doi: 10.4142/jvs.2010.11.4.299
The KA1 kainate receptor (KAR) subunit in the substantia gelatinosa (SG) of the trigeminal subnucleus caudalis (Vc) has been implicated in the processing of nociceptive information from the orofacial region.... -
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- Genomic organization and expression of parkin in Drosophila melanogaster
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Bae YJ, Park KS, Kang SJ
- KMID: 1093612
- Exp Mol Med.
- 2003 Oct;35(5):393-402.
We report here the isolation, characterization on genomic structure and expression of the D. melanogaster homolog of human parkin. The 2,122 bp parkin gene sequence contains six exons that form... -
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- Spatiotemporal regulation of fibroblast growth factor signal blocking for endoderm formation in Xenopus laevis
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Cha SW, Lee JW, Hwang YS, Chae JP, Park KM, Cho HJ, Kim DS, Bae YC, Park MJ
- KMID: 1104809
- Exp Mol Med.
- 2008 Oct;40(5):550-557.
- doi: 10.3858/emm.2008.40.5.550
We have previously shown that the inhibition of fibroblast growth factor (FGF) signaling induced endodermal gene expression in the animal cap and caused the expansion of the endodermal mass in... -
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- Spatio-temporal expression patterns of Runx2 isoforms in early skeletogenesis
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Choi KY, Lee SW, Park MH, Bae YC, Shin HI, Nam SH, Kim YJ, Kim HJ, Ryoo HM
- KMID: 1121096
- Exp Mol Med.
- 2002 Dec;34(6):426-433.
Skeletogenesis occurs through either intramembranous or endochondral ossification. In addition, some parts of the skeletal components maintain their cartilaginous characteristics throughout life without mineralization. Runx2 is known to be... -
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- Identification of abnormal gene expression in bovine transgenic somatic cell nuclear transfer embryos
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Cho J, Kang S, Lee BC
- KMID: 1784643
- J Vet Sci.
- 2014 Jun;15(2):225-231.
- doi: 10.4142/jvs.2014.15.2.225
This study was conducted to investigate the expression of three genes related to early embryonic development in bovine transgenic cloned embryos. To accomplish this, development of bovine transgenic somatic cell... -
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- Expression patterns of beta ig-h3 in chondrocyte differentiation during endochondral ossification
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Han MS, Kim JE, Shin HI, Kim IS
- KMID: 1094125
- Exp Mol Med.
- 2008 Aug;40(4):453-460.
- doi: 10.3858/emm.2008.40.4.453
beta ig-h3 is a TGF-beta-induced extracellular matrix protein which is expressed in many tissues including bones and cartilages. In previous reports, we showed that beta ig-h3 mediates cell adhesion and... -
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- Serum amyloid A inhibits RANKL-induced osteoclast formation
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Oh E, Lee HY, Kim HJ, Park YJ, Seo JK, Park JS, Bae YS
- KMID: 2359881
- Exp Mol Med.
- 2015 Nov;47(11):e194.
- doi: 10.1038/emm.2015.83
When mouse bone marrow-derived macrophages were stimulated with serum amyloid A (SAA), which is a major acute-phase protein, there was strong inhibition of osteoclast formation induced by the receptor activator... -
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- Microarray Analysis of Differentially Expressed Genes between Cysts and Trophozoites of Acanthamoeba castellanii
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Moon EK, Xuan YH, Chung DI, Hong Y, Kong HH
- KMID: 1715738
- Korean J Parasitol.
- 2011 Dec;49(4):341-347.
- doi: 10.3347/kjp.2011.49.4.341
Acanthamoeba infection is difficult to treat because of the resistance property of Acanthamoeba cyst against the host immune system, diverse antibiotics, and therapeutic agents. To identify encystation mediating factors of... -
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- Molecular Characterization of Trypanosoma cruzi Tc8.2 Gene Indicates Two Differential Locations for the Encoded Protein in Epimastigote and Trypomastigote Forms
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Kian D, Lancheros , Damiani IA, Fernandes , Pinge-Filho P, dos Santos MRM, da Silveira JF, Nakamura C, da Silva J, Yamada-Ogatta SF, Yamauchi L
- KMID: 2381767
- Korean J Parasitol.
- 2015 Aug;53(4):483-488.
- doi: 10.3347/kjp.2015.53.4.483
This report describes the molecular characterization of the Tc8.2 gene of Trypanosoma cruzi. Both the Tc8.2 gene and its encoded protein were analyzed by bioinformatics, while Northern blot and RT-PCR... -
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- Differential Expression of TGF-beta Isoforms During Differentiation of HaCaT Human Keratinocyte Cells: Implication for the Separate Role in Epidermal Differentiation
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Cho HR, Hong SB, Kim YI, Lee JW, Kim NI
- KMID: 1778568
- J Korean Med Sci.
- 2004 Dec;19(6):853-858.
- doi: 10.3346/jkms.2004.19.6.853
The three mammalian isoforms of transforming growth factor-beta (TGF-beta1, beta2, beta3) are potent regulators of cell growth, differentiation, and extracellular matrix deposition. To study their role in skin differentiation, we... -
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- Shank 2 expression coincides with neuronal differentiation in the developing retina
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Kim JH, Kim JH, Yang E, Park JH, Yu YS, Kim KW
- KMID: 1088598
- Exp Mol Med.
- 2009 Apr;41(4):236-242.
- doi: 10.3858/emm.2009.41.4.026
The retinal activity for vision requires a precise synaptic connectivity. Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. However, the correlation... -
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- Expression of tyrosine kinase A in the cerebral cortex of postnatal developing rat
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Kwon HJ, Lee KY, Park IK, Park MS, Lee MY, Kim MK
- KMID: 1091197
- J Vet Sci.
- 2005 Sep;6(3):185-189.
Tyrosine kinase A (TrkA)is an essential component of the high affinity nerve growth factor (NGF) receptor necessary to the mediate the biological effects of the neurotrophins, NGF. This study examined... -
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- Distribution and ontogeny of gastrin- and serotonin-immunoreactive cells in the proventriculus of developing chick, Gallus gallus domestica
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Aksoy A, Cinar K
- KMID: 1089340
- J Vet Sci.
- 2009 Mar;10(1):9-13.
- doi: 10.4142/jvs.2009.10.1.9
The ontogeny and distribution of gastrin- and serotonin-immunoreactive (IR) cell in the proventriculus of chicks (Gallus gallus domestica, n = 60) in different growth periods was examined immunohistochemically using antisera... -
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