- The Roles of Stromelysin-1 and the Gelatinase B Gene Polymorphism in Stable Angina
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Kim JS, Park HY, Kwon JH, Im EK, Choi D, Jang Y, Cho SY
- KMID: 1122006
- Yonsei Med J.
- 2002 Aug;43(4):473-481.
- doi: 10.3349/ymj.2002.43.4.473
Matrix metalloproteinases contribute to vascular remodeling by breaking down extracellular-matrix while new matrix is synthesized. Of the variety of MMPs, stromelysin-1 and gelatinase B may have key roles in coronary... -
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- Eosinophil Inflammation of Nasal Polyp Tissue: Relationships with Matrix Metalloproteinases, Tissue Inhibitor of Metalloproteinase-1, and Transforming Growth Factor-beta1
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Park HS, Kim SS, Kim HA, Suh YJ, Lee SK, Nahm DH, Lee YM
- KMID: 1099801
- J Korean Med Sci.
- 2003 Feb;18(1):97-102.
- doi: 10.3346/jkms.2003.18.1.97
Eosinophil and mast cell infiltrations are consistent findings in nasal polyp tissue. Previous studies have shown that matrix metalloproteinases (MMPs) may be involved in eosinophil infiltration in airway mucosa of... -
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- Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression
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Hur JH, Park MJ, Park IC, Yi DH, Rhee CH, Hong SI, Lee SH
- KMID: 1128630
- J Korean Med Sci.
- 2000 Jun;15(3):309-314.
- doi: 10.3346/jkms.2000.15.3.309
To evaluate possible roles of matrix metalloproteinase (MMP)-1, -2, tissue inhibitor of metalloproteinase (TIMP)-1, -2 and membrane-type-1 matrix metalloproteinase (MT1-MMP) in invasion of human gliomas, expressions of these proteins were... -
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- Correlation between expression of matrix metalloproteinase-2 (MMP-2), and matrix metalloproteinase-9 (MMP-9) and angiogenesis in colorectal adenocarcinoma
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Kim TS, Kim YB
- KMID: 646304
- J Korean Med Sci.
- 1999 Jun;14(3):263-270.
- doi: 10.3346/jkms.1999.14.3.263
Matrix metalloproteinases-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9), which degrade extracellular matrix, are believed to play a crucial role in tumor invasion and metastasis. Angiogenesis is also perceived as an important... -
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- Reduced expression of tissue inhibitor of metalloproteinase in nodal metastasis of stomach cancer
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Ko BK, Cho HR, Choi DW, Nam CW, Park CJ, Kim GY, Kim SS, Woo YJ, Huh J, Kim MY
- KMID: 1745551
- J Korean Med Sci.
- 1998 Jun;13(3):286-290.
- doi: 10.3346/jkms.1998.13.3.286
The matrix metalloproteinases (MMPs) have been associated with tumor cell invasion and metastasis of human cancers by mediating the degradation of extracellular matrix components. Therefore, these enzymes and their... -
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- Role of tissue inhibitors of metalloproteinases (TIMPs) in colorectal carcinoma
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Joo YE, Seo KS, Kim J, Kim HS, Rew JS, Park CS, Kim SJ
- KMID: 1731316
- J Korean Med Sci.
- 1999 Aug;14(4):417-423.
- doi: 10.3346/jkms.1999.14.4.417
Increased production of matrix metalloproteinases (MMPs) has been associated with increases in invasive and metastatic potential in many types of human carcinoma. Tissue inhibitors of metalloproteinase (TIMP)-1 inhibits most interstitial... -
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- Tetraspanin CD9 induces MMP-2 expression by activating p38 MAPK, JNK and c-Jun pathways in human melanoma cells
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Hong IK, Kim YM, Jeoung DI, Kim KC, Lee H
- KMID: 1056236
- Exp Mol Med.
- 2005 Jun;37(3):230-239.
Expression of matrix metalloproteinase-2 and -9 (MMP-2 and MMP-9), which correlates with tumor invasion and metastasis, has been known to be regulated by several intracellular signaling pathways. Since the CD9... -
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- Polymorphism of Matrix Metalloproteinase-3 Promoter Gene as a Risk Factor for Coronary Artery Lesions in Kawasaki Disease
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Park JA, Shin KS, Kim YW
- KMID: 1712741
- J Korean Med Sci.
- 2005 Aug;20(4):607-611.
- doi: 10.3346/jkms.2005.20.4.607
Kawasaki disease (KD) is a major cause of acquired coronary artery diseases in childhood. The serum levels of matrix metalloproteinase (MMP)-3 and MMP-9 in KD have been reported to be... -
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- The Changes of Matrix Metalloproteinase-9 Expression in the Gastric Antral Mucosa after Helicobacter pylori Eradication: Immunohistochemical Study
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Ahn HS, Kim IH, Lee SO, Kang MJ, Kim DG, Lee ST
- KMID: 772611
- Korean J Gastroenterol.
- 2004 Feb;43(2):90-95.
BACKGROUND/AIMS: In this study, we analysed the changes of matrix metalloproteinase-9 (MMP-9) expression in the gastric antral epithelium in respect to H. pylori eradication. METHODS: Twenty patients with H.... -
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- The Role of Angiostatin, Vascular Endothelial Growth Factor, Matrix Metalloproteinase 9 and 12 in the Angiogenesis of Hepatocellular Carcinoma
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Kim S, Park HS, Son HJ, Moon WS
- KMID: 760532
- Korean J Hepatol.
- 2004 Mar;10(1):62-72.
BACKGROUND/AIMS: Tumor angiogenesis, a major requirement for tumor growth and metastasis, is regulated by pro- and anti-angiogenic factors. Hepatocellular carcinoma (HCC) has become a common malignant tumor worldwide. It... -
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- Lung Matrix Metalloproteinase-9 Correlates with Cigarette Smoking and Obstruction of Airflow
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Kang MJ, Oh YM, Lee JC, Kim DG, Park MJ, Lee MG, Hyun IG, Han SK, Shim YS, Jung KS
- KMID: 1086738
- J Korean Med Sci.
- 2003 Dec;18(6):821-827.
- doi: 10.3346/jkms.2003.18.6.821
Cigarette smoking is the most important risk factor for obstruction of airflow in chronic obstructive pulmonary disease (COPD). Matrix metalloproteinases (MMPs) or an imbalance between MMPs and their inhibitors, the... -
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- Expression of Epidermal Growth Factor Receptor, ErbB2 and Matrix Metalloproteinase-9 in Hepatolithiasis and Cholangiocarcinoma
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Kim HJ, Kim JS, Kang CD, Lee SJ, Kim JY, Yeon JE, Park JJ, Shim JJ, Byun KS, Bak YT, Lee CH
- KMID: 772717
- Korean J Gastroenterol.
- 2005 Jan;45(1):52-59.
BACKGROUND/AIMS: Hepatolithiasis is a common disease in East Asia and presents as a histological feature of proliferative glands containing mucin. 5-10% of hepatolithiasis is known to be associated with... -
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- Ox-LDL suppresses PMA-induced MMP-9 expression and activity through CD36-mediated activation of PPAR-gamma
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Lee KJ, Kim HA, Kim PH, Lee HS, Ma KR, Park JH, Kim DJ, Hahn JH
- KMID: 1103320
- Exp Mol Med.
- 2004 Dec;36(6):534-544.
During chronic inflammatory response, mono- cytes/macrophages produce 92-kDa matrix metalloproteinase-9 (MMP-9), which may contribute to their extravasation, migration and tissue remodeling. Activation of peroxisome proliferator- activated factor receptor-gamma (PPAR-gamma) has... -
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- Serologic and histopathologic study of Chlamydia pneumoniae infection in atherosclerosis: a possible pathogenetic mechanism of atherosclerosis induced by Chlamydia pneumoniae
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Song YG, Kwon HM, Kim JM, Hong BK, Kim DS, Huh AJ, Chang KH, Kim HY, Kang TS, Lee BK, Choi DH, Jang YS, Kim HS
- KMID: 711753
- Yonsei Med J.
- 2000 Jun;41(3):319-327.
- doi: 10.3349/ymj.2000.41.3.319
Chronic infection and inflammation have recently been implicated as important etiologic agents for atherosclerosis in general and, in particular, ischemic heart disease. Several agents have been suggested as possible candidates... -
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