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GABAergic neuronal development in the embryonic mesencephalon of mice

This study presents neurogenesis and neuronal migration patterns of gamma-aminobutyric acid-ergic (GABAergic) neurons during mesencephalic development of mouse. After neurons from embryonic day (E) 10-16 were labelled by a single...
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Colocalization of GABA and Glycine within the Neurons of the Rat Retina

Son WH, Oh SJ, Kim IB, Chun MH, Jung JW

  • KMID: 2224609
  • Korean J Anat.
  • 1997 Dec;30(6):695-704.
The role of GABA or glycine as an inhibitory neurotransmitter is well established, and GABAergic or glycinergic neurons appear to play an important role in the mammalian retinas. It has...
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The effect of µ-opioid receptor activation on GABAergic neurons in the spinal dorsal horn

Kim YR, Shim HG, Kim CE, Kim SJ

The superficial dorsal horn of the spinal cord plays an important role in pain transmission and opioid activity. Several studies have demonstrated that opioids modulate pain transmission, and the activation...
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Direct Corticosteroid Modulation of GABAergic Neurons in the Anterior Hypothalamic Area of GAD65-eGFP Mice

Shin SY, Han TH, Lee SY, Han SK, Park JB, Erdelyi F, Szabo G, Ryu PD

Corticosterone is known to modulate GABAergic synaptic transmission in the hypothalamic paraventricular nucleus. However, the underlying receptor mechanisms are largely unknown. In the anterior hypothalamic area (AHA), the sympathoinhibitory center...
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Immunocytochemical Studies of Calbindin D-28k and Parvalbumin-Containing GABAergic Neurons in the Midbrain of the Cat

Kim JJ, Jeong SB, Kim NH, Ahn GH, Chung YY, Moon JS, Chang IY, Kim HS

  • KMID: 2071859
  • Korean J Phys Anthropol.
  • 2000 Jun;13(2):201-211.
This study was carried out to investigate the morphology, distribution and co-localization of calbindin D-28k and parvalbumin-containing GABAergic cells in the midbrain of the cat. The results obtain by immunocytochemical...
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Excitotoxic Cell Death in Cultured Retinal Neurons

Yoon YH, Shim MJ, Lee J

  • KMID: 2123633
  • J Korean Ophthalmol Soc.
  • 1997 Nov;38(11):1987-1999.
We examined excitotoxicity, putatively a major mechanism of ischemic neuronal death, in primary rat retinal cultures. Retinal cultures were prepared from newborn rats (day 1 or 2). Exposure of these...
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Aucubin Promotes Differentiation of Neural Precursor Cells into GABAergic Neurons

Song M, Kim H, Park S, Kwon H, Joung I, Kim Kwon Y

Aucubin is a small compound naturally found in traditional medicinal herbs with primarily anti-inflammatory and protective effects. In the nervous system, aucubin is reported to be neuroprotective by enhancing neuronal...
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Differentiation of neuroepithelial progenitor cells implanted into newborn rat brain striatum

Kwon SC, Park JS, Lee JJ, Nam TS, Yeon DS

  • KMID: 1606833
  • Korean J Physiol Pharmacol.
  • 2001 Feb;5(1):9-17.
It has been demonstrated that multipotent neuronal progenitor cells can be isolated from the developing or adult CNS and proliferated in vitro in response to epidermal growth factor. The present study was undertaken...
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The Relationship of Alcohol and Crime in Korea

Lee KS

No abstract available.
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Immunocytochemical Study on the Development of the Rod Pathway in the Rat Retina

Lim EJ, Lee EJ, Chun MH

  • KMID: 1610768
  • Korean J Anat.
  • 2003 Aug;36(4):331-342.
Rod bipolar cells constitute the second-order neuron in the rod pathway. Previous investigations of the rat retina have evaluated the development of other components of the rod pathway namely the...
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The changes of mitochondrial cytochrome c and GABAergic neuron in neuropathic pain model

Kim WS, Park JY, Kim TK, Baik SW

BACKGROUND: Role of cytochrome c (Cyt c) is an apoptogenic agent under certain conditions. The mitochondrial permeability transition pore (MPTP) plays an important role in cell death since it opens,...
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Interhemispheric Modulation on Afferent Sensory Transmission to the Ventral Posterior Medial Thalamus by Contralateral Primary Somatosensory Cortex

Jung SC, Choi IS, Cho JH, Kim JH, Bae YC, Lee MG, Shin HC, Choi BJ

  • KMID: 2285296
  • Korean J Physiol Pharmacol.
  • 2004 Jun;8(3):129-132.
Single unit responses of the ventral posterior medial (VPM) thalamic neurons to stimulation were monitored in anesthetized rats during activation of contralateral primary somatosensory (SI) cortex by GABA antagonist. The...
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Basal Forebrain Cholinergic Deficits Reduce Glucose Metabolism and Function of Cholinergic and GABAergic Systems in the Cingulate Cortex

Jeong DU, Oh JH, Lee JE, Lee J, Cho ZH, Chang JW, Chang WS

PURPOSE: Reduced brain glucose metabolism and basal forebrain cholinergic neuron degeneration are common features of Alzheimer's disease and have been correlated with memory function. Although regions representing glucose hypometabolism in...
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In Vivo Roles of a Patient-Derived Induced Pluripotent Stem Cell Line (HD72-iPSC) in the YAC128 Model of Huntington's Disease

Jeon I, Choi C, Lee N, Im W, Kim M, Oh SH, Park IH, Kim HS, Song J

  • KMID: 2054559
  • Int J Stem Cells.
  • 2014 May;7(1):43-47.
Induced pluripotent stem cells (iPSCs) generated from somatic cells of patients can provide immense opportunities to model human diseases, which may lead to develop novel therapeutics. Huntington's disease (HD) is...
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Roles of Stem Cell Factor and c-kit Receptor in the Development of Cerebellar GABAergic Neurons

Won YJ, Lee JH, Im JO, Yun SY, Hwang SJ, Kim D, Hong HN

  • KMID: 2092844
  • Korean J Anat.
  • 2004 Oct;37(5):481-490.
Evidence that Stem cell factor (SCF) and c-Kit receptor tyrosine kinase are expressed in the cerebellum during postnatal development, suggests a possible contribution of the SCF/Kit signaling pathway in the...
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Gephyrin: a central GABAergic synapse organizer

Choii G, Ko J

Gephyrin is a central element that anchors, clusters and stabilizes glycine and gamma-aminobutyric acid type A receptors at inhibitory synapses of the mammalian brain. It self-assembles into a hexagonal lattice...
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Reexamination of Dopaminergic Amacrine Cells in the Rabbit Retina: Confocal Analysis with Double- and Triple-labeling Immunohistochemistry

Lee JW, Lim MY, Park YS, Park SJ, Kim IB

Dopaminergic amacrine cells (DACs) are among the most well-characterized neurons in the mammalian retina, and their connections to AII amacrine cells have been described in detail. However, the stratification of...
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Current clinical application of dexmedetomidine for sedation and anesthesia

Kim DS, Na HS, Lee JH, Shin YD, Shim JK, Shin HW, Kang H, Joung KW

Many sedatives are used clinically and include benzodiazepines, barbiturates, antihistamines, propofol, and alpha-2-agonist. Benzodiazepines activate GABA neuronal receptors in the brain and present sedating, hypnotic, anxiolytic, amnestic, and anticonvulsant effects,...
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