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Individual-Level Lesion-Network Mapping to Visualize the Effects of a Stroke Lesion on the Brain Network: Connectograms in Stroke Syndromes

Lim JS, Lee JJ, Woo CW, Song J, Oh MS, Yu KH, Lee BC

BACKGROUND AND PURPOSE: Similar-sized stroke lesions at similar locations can have different prognoses in clinical practice. Lesion-network mapping elucidates network-level effects of lesions that cause specific neurologic symptoms and signs,...
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A New Metabolic Network Correlated with Olfactory and Executive Dysfunctions in Idiopathic Rapid Eye Movement Sleep Behavior Disorder

Yoon EJ, Lee JY, Nam H, Kim HJ, Jeon B, Jeong JM, Kim YK

BACKGROUND AND PURPOSE: To identify a metabolic network reflecting neurodegeneration in patients with idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD). METHODS: We recruited a prospective cohort comprising patients with...
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Neurobiological understanding of suicide

Kim S, Lee KU

Suicide is a complex phenomenon resulting from interactions between individual vulnerabilities and socio-environmental factors. The current review primarily focuses on research into the serotonin system, hypothalamic-pituitary-adrenal axis, neurotrophic factors, lipid...
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Understanding Neurogastroenterology From Neuroimaging Perspective: A Comprehensive Review of Functional and Structural Brain Imaging in Functional Gastrointestinal Disorders

Kano M, Dupont P, Aziz Q, Fukudo S

  • KMID: 2422842
  • J Neurogastroenterol Motil.
  • 2018 Oct;24(4):512-527.
  • doi: 10.5056/jnm18072
This review provides a comprehensive overview of brain imaging studies of the brain-gut interaction in functional gastrointestinal disorders (FGIDs). Functional neuroimaging studies during gut stimulation have shown enhanced brain responses...
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Regional Brain Activity During Rest and Gastric Water Load in Subtypes of Functional Dyspepsia: A Preliminary Brain Functional Magnetic Resonance Imaging Study

Chen Y, Wang R, Hou B, Feng F, Fang X, Zhu L, Sun X, Wang Z, Ke M

  • KMID: 2413103
  • J Neurogastroenterol Motil.
  • 2018 Apr;24(2):268-279.
  • doi: 10.5056/jnm17076
BACKGROUND/AIMS: Functional dyspepsia (FD) remains a great clinical challenge since the FD subtypes, defined by Rome III classification, still have heterogeneous pathogenesis. Previous studies have shown notable differences in visceral...
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Current Knowledge and Clinical Application of Brain Imaging in Alzheimer's Disease

Kang DW, Lim HK

Alzheimer's disease (AD) is a debilitating syndrome with cognitive decline and impairment in daily activities. Although clinical assessment forms the basis for diagnosing AD, structural and functional brain imaging tools...
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How to Perform and Interpret Functional Magnetic Resonance Imaging Studies in Functional Gastrointestinal Disorders

Lee IS, Preissl H, Enck P

  • KMID: 2433520
  • J Neurogastroenterol Motil.
  • 2017 Apr;23(2):197-207.
  • doi: 10.5056/jnm16196
Functional neuroimaging studies have revealed the importance of the role of cognitive and psychological factors and the dysregulation of the brain-gut axis in functional gastrointestinal disorder patients. Although only a...
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Comprehensive Evaluation of Internet Gaming Disorder : Clinical and Neurobiological Assessments

Paik SH, Cho H, Choi JS, Choi SW, Kim DJ

A growing body of evidence supports that Internet gaming disorder (IGD) is considered as ‘behavioral addiction’ with neurobiological alterations. We have reviewed previous research into the clinical and neurobiological features...
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Movement Disorders Following Cerebrovascular Lesions in Cerebellar Circuits

Choi SM

Cerebellar circuitry is important to controlling and modifying motor activity. It conducts the coordination and correction of errors in muscle contractions during active movements. Therefore, cerebrovascular lesions of the cerebellum...
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Functional Imaging of Tinnitus

Kim JH, Lee HJ

Tinnitus is an auditory phantom characterized by the perception of sound without the presence of an external acoustical source. The peripheral auditory system is considered to contribute to the initiation...
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Non-Conscious Perception of Emotions in Psychiatric Disorders: The Unsolved Puzzle of Psychopathology

Lee SA, Kim CY, Lee SH

Psychophysiological and functional neuroimaging studies have frequently and consistently shown that emotional information can be processed outside of the conscious awareness. Non-conscious processing comprises automatic, uncontrolled, and fast processing that...
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Functional Neuroimaging in Neuro-Otology

Song JJ

Neuro-otologic symptoms such as dizziness, hearing loss, or tinnitus give rise to peripheral change-induced neuroplasticity or central pathology-induced structural or functional changes. In this regard, functional neuroimaging modalities such as...
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Modulating Neural Network through rTMS

Yoo WK

Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive method to produce potent changes in cortical excitability. Therefore, the application of rTMS was recently proposed to promote functional recovery in stroke...
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Advances in Functional Connectomics in Neuroscience : A Focus on Post-Traumatic Stress Disorder

Park S, Jeong HS, Lyoo IK

Recent breakthroughs in functional neuroimaging techniques have launched the quest of mapping the connections of the human brain, otherwise known as the human connectome. Imaging connectomics is an umbrella term...
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Cognition in Restless Legs Syndrome

Jung KY

Cognition is the mental abilities related to knowledge which includes attention, memory, language, judgment, and decision making. Cognitive function can be affected by several factors including attention, emotion, and sleep....
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Abnormal Brain Activity in Social Reward Learning in Children with Autism Spectrum Disorder: An fMRI Study

Choi US, Kim SY, Sim HJ, Lee SY, Park SY, Jeong JS, Seol KI, Yoon HW, Jhung K, Park JI, Cheon KA

PURPOSE: We aimed to determine whether Autism Spectrum Disorder (ASD) would show neural abnormality of the social reward system using functional MRI (fMRI). MATERIALS AND METHODS: 27 ASDs and 12 typically...
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Electroencephalographic Characteristics of Alcohol Dependent Patients: 3-Dimensional Source Localization

Seo S, Im S, Lee SG, Shin CJ

OBJECTIVES: The power spectral analysis of electroencephalogram has been widely used to reveal the pathophysiology of the alcoholic brain. However, the results were not consistent and the three dimensional study...
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Chronometry TMS in Language Network

Ahn HJ, Yoo WK

The purpose of this review is to introduce a new mapping technique, the chronometry transcranial magnetic stimulation (TMS), which can be used to delineate detailed time information of specific functioning...
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Functional Neuroimaging of Tinnitus: State-of-the-Art

Song JJ

Non-pulsatile subjective tinnitus is a phantom sound percept without any objective physical sound source. Recent advances in tinnitus research have suggested central rather than peripheral changes as the culprit of...
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Serotonin and Mental Disorders: A Concise Review on Molecular Neuroimaging Evidence

Lin SH, Lee LT, Yang YK

Serotonin is one of the most important neurotransmitters influencing mental health and, thus, is a potential target for pharmaco-logical treatments. Functional neuroimaging techniques, such as positron-emission tomography (PET) and single...
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