- Modulation of DNA methylation by one-carbon metabolism: a milestone for healthy aging
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Choi SW, Friso S
- KMID: 2545179
- Nutr Res Pract.
- 2023 Aug;17(4):597-615.
- doi: 10.4162/nrp.2023.17.4.597
Healthy aging can be defined as an extended lifespan and health span. Nutrition has been regarded as an important factor in healthy aging, because nutrients, bioactive food components, and diets... -
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- A lifelong exposure to a Western-style diet, but not aging, alters global DNA methylation in mouse colon
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Choi SW, Tammen SA, Liu Z, Friso S
- KMID: 2313851
- Nutr Res Pract.
- 2015 Aug;9(4):358-363.
- doi: 10.4162/nrp.2015.9.4.358
BACKGROUND/OBJECTIVES: Previous studies have indicated that when compared to young mice, old mice have lower global DNA methylation and higher p16 promoter methylation in colonic mucosa, which is a common... -
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- Iron Supplementation Reverses the Reduction of Hydroxymethylcytosine in Hepatic DNA Associated With Chronic Alcohol Consumption in Rats
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Tammen SA, Park JE, Shin PK, Friso S, Chung J, Choi SW
- KMID: 2367564
- J Cancer Prev.
- 2016 Dec;21(4):264-270.
- doi: 10.15430/JCP.2016.21.4.264
BACKGROUND: Alcohol is known to affect two epigenetic phenomena, DNA methylation and DNA hydroxymethylation, and iron is a cofactor of ten-eleven translocation (TET) enzymes that catalyze the conversion from methylcytosine... -
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