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Does Recombinant Human Bone Morphogenic Protein 2 Affect Perioperative Blood Loss after Lumbar and Thoracic Spinal Fusion?

Wanderman , Carlson B, Robinson W, Bydon M, Yaszemski , Huddleston P, Freedman B

STUDY DESIGN: Retrospective cohort design. PURPOSE: This study aimed to determine whether recombinant human bone morphogenic protein 2 (rhBMP-2) reduces total perioperative blood loss during lumbar and thoracic fusion. OVERVIEW OF LITERATURE:...
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An Ovariectomy-Induced Rabbit Osteoporotic Model: A New Perspective

Wanderman , Mallet C, Giambini H, Bao N, Zhao C, An KN, Freedman B, Nassr A

STUDY DESIGN: Experimental Animal Model. PURPOSE: The aim of our study was to validate a pure bilateral ovariectomy (OVX) female New Zealand white rabbit model of postmenopausal osteoporosis utilizing animal-sparing in...
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Combat-Related Intradural Gunshot Wound to the Thoracic Spine: Significant Improvement and Neurologic Recovery Following Bullet Removal

Louwes TM, Ward WH, Lee KH, Freedman B

The vast majority of combat-related penetrating spinal injuries from gunshot wounds result in severe or complete neurological deficit. Treatment is based on neurological status, the presence of cerebrospinal fluid (CSF)...
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An Objective and Reliable Method for Identifying Sarcopenia in Lumbar Spine Surgery Patients: Using Morphometric Measurements on Computed Tomography Imaging

Tomov M, Alvi MA, Elminawy M, Currier B, Yaszemski M, Nassr A, Huddleston P, Sebastian A, Bydon M, Freedman B

Study Design: A retrospective observational study. Purpose: Establish a quantifiable and reproducible measure of sarcopenia in patients undergoing lumbar spine surgery based on morphometric measurements from readily available preoperative computed tomography...
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Reducing Stroke Risk in Atrial Fibrillation: Adherence to Guidelines Has Improved, but Patient Persistence with Anticoagulant Therapy Remains Suboptimal

Lowres N, Giskes K, Hespe C, Freedman B

Atrial fibrillation (AF) is a significant risk factor for avoidable stroke. Among high-risk patients with AF, stroke risk can be mitigated using oral anticoagulants (OACs), however reduction is largely contingent...
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Anterior Lumbar Interbody Fusion: Two-Year Results with a Modular Interbody Device

Jackson KL, Yeoman C, Chung WM, Chappuis J, Freedman B

STUDY DESIGN: Retrospective case series. PURPOSE: To present radiographic outcomes following anterior lumbar interbody fusion (ALIF) utilizing a modular interbody device. OVERVIEW OF LITERATURE: Though multiple anterior lumbar interbody techniques have proven...
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A Comparison of Computed Tomography Measures for Diagnosing Cervical Spinal Stenosis Associated with Myelopathy: A Case-Control Study

Freedman B, Hoffler CE, Cameron BM, Rhee JM, Bawa M, Malone DG, Bent M, Yoon TS

STUDY DESIGN: Retrospective comparative study. PURPOSE: To assess differences in computed tomography (CT) imaging parameters between patients with cervical myelopathy and controls. OVERVIEW OF LITERATURE: There is a lack of information regarding...
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Nurse Led Smartphone Electrographic Monitoring for Atrial Fibrillation after Ischemic Stroke: SPOT-AF

Yan B, Tu H, Lam C, Swift C, Ho MS, Mok VC, Sui Y, Sharpe D, Ghia D, Jannes J, Davis S, Liu X, Freedman B

Background and Purpose Paroxysmal atrial fibrillation (PAF) underlying acute stroke frequently evades detection by standard practice, considered to be a combination of routine electrocardiogram (ECG) monitoring, and 24-hour Holter recordings....
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Does Subcutaneous Infiltration of Liposomal Bupivacaine Following Single-Level Transforaminal Lumbar Interbody Fusion Surgery Improve Immediate Postoperative Pain Control?

Tomov M, Tou K, Winkel R, Puffer R, Bydon M, Nassr A, Huddleston P, Yaszemski , Currier B, Freedman B

STUDY DESIGN: Retrospective case-control study using prospectively collected data. PURPOSE: Evaluate the impact of liposomal bupivacaine (LB) on postoperative pain management and narcotic use following standardized single-level low lumbar transforaminal lumbar...
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