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Calcium-dependent protein kinases are potential targets for Toxoplasma gondii vaccine

Foroutan M, Ghaffarifar F

Toxoplasma gondii belongs to the Apicomplexa phylum that caused a widespread zoonotic infection in wide range of intermediate hosts. Over one-third of the world's population are latently infected with T....
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Recent progress in microneme-based vaccines development against Toxoplasma gondii

Foroutan M, Zaki L, Ghaffarifar F

Toxoplasmosis is a cosmopolitan zoonotic disease, which infect several warm-blooded mammals. More than one-third of the human population are seropositive worldwide. Due to the high seroprevalence of Toxoplasma gondii infection...
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In-depth computational analysis of calcium-dependent protein kinase 3 of Toxoplasma gondii provides promising targets for vaccination

Majidiani H, Soltani S, Ghaffari AD, Sabaghan M, Taghipour A, Foroutan M

Purpose: The Toxoplasma gondii calcium-dependent protein kinase-3 (CDPK3) is a key enzyme for parasite egress, control of calcium-dependent permeabilization in parasitophorous vacuole membrane and tissue cyst formation. In this study,...
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A systematic review and meta-analysis of the prevalence of toxoplasmosis in hemodialysis patients in Iran

Foroutan M, Rostami A, Majidiani , Riahi SM, Khazaei S, Badri M, Yousefi E

OBJECTIVES: Toxoplasmosis is a parasitic disease that occurs worldwide, with a wide range of complications in immunocompromised patients. This systematic review and meta-analysis was performed to evaluate the seroprevalence of...
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Rhoptry antigens as Toxoplasma gondii vaccine target

Foroutan M, Ghaffarifar F, Sharifi Z, Dalimi A, Jorjani O

Toxoplasmosis is a cosmopolitan zoonotic infection, caused by a unicellular protozoan parasite known as Toxoplasma gondii that belongs to the phylum Apicomplexa. It is estimated that over one-third of the...
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