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Effects of Ketamine and Pentobarbitone on Degeneration of Oocyte and of Granulosa Cells in Mouse Ovary

Kim JH, Yoon YD

  • KMID: 2304578
  • Korean J Fertil Steril.
  • 1998 Aug;25(2):179-187.
In mammal, lots of follicles start simultaneously their growth but only a few oocytes are ovulated in every sexual cycles. Most of matured and grown oocytes are destined to degenerate...
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Morphological Study on the Radiation-induced Follicular Atresia and the Follicular Macrophage

Song KI, Noh HT, Rhee YE, Son SK, Kim WS, Kim SI

  • KMID: 2272404
  • Korean J Obstet Gynecol.
  • 2004 Oct;47(10):1940-1948.
OBJECTIVE: It is well known that X-ray induces follicular atresia, but the exact mechanism of atresia is not still unveiled completely. In addition, the role of macrophage related with clean-up...
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Follicular Atresia and Macrophages in the Porcine Ovary; Immunohistochemical and Transmission Electron Microscopic Study

Kim WS, Han SR, Kim SI, Park CS

  • KMID: 1566749
  • Korean J Anat.
  • 2004 Feb;37(1):9-18.
Apoptosis of granulosa cells leads follicular atresia and macrophages have an important role during the apoptotic process. However, the propagation of apoptosis within the follicle, the ways of elimination of...
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TNFalpha and TNFR2 Immunohistochemistry During Ovarian Follicular Development and Atresia in the Rat

Han SR, Son SK, Yang YS, Kim WS

  • KMID: 2224491
  • Korean J Anat.
  • 2005 Dec;38(6):553-559.
Tumor necrosis factor alpha (TNFalpha) is an intraovarian cytokine that may play a role in ovarian development and function. Identification of ovarian TNFalpha receptors provides support for establishing a role...
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Expression of bcl-2 and bax mRNAs during follicular development and atresia in the rat ovary

Koh PO, Kang SS, Choi WS, Kwak SD, Cho GJ

  • KMID: 2224593
  • Korean J Anat.
  • 1999 Feb;32(1):43-52.
In the mammalian ovary, follicular atresia occurs through apoptosis. Apoptosis is known as the physiological cell death, which is regulated by bcl-2 gene family. In the bcl-2 gene family, bcl-2/bcl-xLong...
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Distribution and Role of Ovarian Follicle Macrophage in Rat Ovarian Follicular Atresia

Yang YS, Noh HT, Rhee YE, Son SK, Cho KJ, Choi HI, Kim SI, Kim WS

  • KMID: 2272705
  • Korean J Obstet Gynecol.
  • 2005 Oct;48(10):2353-2366.
OBJECTIVE: Ovarian follicular atresia is initiated from ovarian granulosa cell apoptosis and macrophages exert their effects directly and/or indirectly on follicular atresia by phagocytosis of apoptotic bodies and secretion of...
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Expression of CDK inhibitor (CDI) p57 and bcl-2 mRNA during follicular development and follicular atresia in the rat ovary

Cho GJ, Koh PO, Kwak SD, Kim MO, Lee BH, Choi WS, Baik SH

  • KMID: 1530096
  • Korean J Anat.
  • 1998 Jun;31(3):361-370.
In mammals, the ovary proceeds follicular development and atresia during the reproductive cycle. Follicular atresia occurs through apoptosis, programmed cell death (PCD) which is mediated by gene controlling apoptosis and...
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Electron Microscopic Studies on Granulosa Cell Apoptosis by gamma-Radiation in the Mouse Ovary

Lee JM, Lee CJ, Song KW, Park MH, Kang JS

  • KMID: 2262762
  • Korean J Obstet Gynecol.
  • 2002 May;45(5):828-835.
OBJECTIVES: Most of the follicles in mammalian ovaries are degenerated throughout the whole reproductive life. The present study was carried out to know the effect of gamma-irradiation on the ultrastructural...
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Expression of Inhibin in the Whole-body gamma-irradiated Mouse Ovary

Kim SS, Lee CJ, Yoon HT, Yoon YD

  • KMID: 1511388
  • Korean J Fertil Steril.
  • 2006 Mar;33(1):35-44.
OBJECTIVE: The purposes of the present study were to investigate the effect of gamma-radiation on the expression of inhibin-alpha proteins and genes for inhibin alpha, betaA, and betain the ovary. METHODS:...
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Increased Serum Level of Inhibin in Oligo-amenorrheic Women with Polycystic Ovaries

Roh JS, Yoo JB, Moon H, Hwang YY

  • KMID: 2085110
  • Korean J Fertil Steril.
  • 1998 Apr;25(1):93-102.
Normal and abnormal follicular growth and steroidogenesis depend on gonadotropins as well as intraovarian peptides, which may mediate or potentiate gonadotropin action. Inhibin also affect follicular development and steroidogenesis and...
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The Immunologic Expression of Apoptosis Related Proteins and Apoptotic Cells in Human Ovarian Follicles

Park SR, Lee BS, Yang WI, Kim JH, Park BJ, Park KH, Cho DJ, Song CH

  • KMID: 1566255
  • Korean J Fertil Steril.
  • 2002 Sep;29(3):195-200.
OBJECTIVE: To investigate the expression of apoptosis related proteins and apoptotic cells on the human ovarian follicles. MATERIALS AND METHODS: Thirty five Formalin-fixed paraffin-embedded human ovarian tissue blocks were selected from...
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The Expression of Apoptosis Related Genes bel-2, TRPM-2 in Luteinized Human Granulosa Cells

Lee BS, Choi EA, Chang KH, Kim JY, Bae SW, Park KH, Cho DJ, Lee K, Kim JW, Song CH

  • KMID: 1531514
  • Korean J Fertil Steril.
  • 1997 Aug;24(2):267-271.
Apoptosis, programmed cell death, is posulated to occur in granulosa cells in ovarian follicular atresia. bcl-2 gene serves as protector from apoptosis and, thus, is associated with increased cell survival....
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The expression of BH3-only Bcl-2 family members in mouse ovary and influence of gonadotropin on Nix expression in granulosa cells

Hwang SJ, Kim MR, Kim JH

  • KMID: 2272801
  • Korean J Obstet Gynecol.
  • 2006 Feb;49(2):408-414.
OBJECTIVE: In the ovary apoptosis eliminates granulosa cells (GC) during follicle atresia. While we identified many cell death regulatory molecules not yet characterized in the ovary, of particular interest were...
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Low-dose Radiation-induced Hormetic Effect in the Rat Ovarian Follicle

Lee WJ, Son SK, Lee MA, Yang YS, Kim WS

  • KMID: 2283411
  • Korean J Phys Anthropol.
  • 2007 Sep;20(3):201-211.
Hormesis is the generally-favorable biological responses to low exposures to toxins and other stressors. Radiation hormesis is the theory that ionizing radiation is benign at low levels of exposure, and...
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High Correlation of Serum Inhibin A and B with Gonadotropin Levels in Oligo-amenorrheic Women with Polycystic Ovary Syndrome

Roh JS, Ji IW, Son BR, Kim HS

  • KMID: 2075833
  • Korean J Obstet Gynecol.
  • 1999 Jul;42(7):1550-1555.
OBJECTIVES: Normal and abnormal follicular growth and steroidogenesis depend on gonadotropins as well as intraovarian peptides. Inhibin also affect follicular development and steroidogenesis and may play a role in dominant...
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Effects of GnRH Agonist Used for Ovarian Hyperstimulation in Human IVF-ET on the Apoptosis of Preovulatory Follicular Cells

Yang HW, Kwon HC, Hwang KJ, Park JM, Oh KS, Yoon YD

  • KMID: 2085117
  • Korean J Fertil Steril.
  • 1999 Apr;26(1):55-65.
There have been many reports to date regarding the role of GnRH as a local regulatory factor of ovarian function as studies of human and rat ovaries revealed GnRH and...
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HCG attenuates ATP induced apoptosis in cultured human luteinized granulosa cells (hLGCs)

Kim MR, Park DW, Kim YA, Cho TS, Hwang KJ, Min CK, Jo MY

  • KMID: 2262671
  • Korean J Obstet Gynecol.
  • 2002 Mar;45(3):475-483.
OBJECTIVE: To determine the effects of hCG on extracellular ATP induced apoptosis in cultured human luteinized granulosa cells (hLGCs) METHODS: The addition of various concentrations of ATP (0, 0.1, 0.25, 0.5,...
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