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Flumazenil-induced Ballism

Kim JS, Ko SB, Choi YB, Lee KS

Flumazenil, an imidazobenzodiazepine, is the first benzodiazepine antagonist and is being used to reverse the adverse pharmacological effects of benzodiazepine. There have been a few reports on the central nevous...
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Aphasic Status Epilepticus after Flumazenil Injection

Cho S, Kim BK, Kwon O, Park JM, Kang K, Lee WW, Lee JJ

No abstract available.
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Antagonistic Effect of Flumazenil on the Prolonged Oversedation after Sevoflurane Based Anesthesia: A case report

Hwang K, Kim H, Lee S

Prolonged oversedation occurs frequently in postoperative care units, and sometimes delays transfer to normal units. Flumazenil is a known reversal drug for benzodiazepines, and is used to reverse the oversedation...
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The Effects of Flumazenil after Midazolam Sedation during Spinal Anesthesia

Lee KW, Kim JS, Song KS, Park MK, Park KH, Kim KS

The effects of flumazenil, a benzodiazepine antagonist were evaluated in a clinical study in which midazolam (0.1 mg/kg) was used as a sedative agent during the spinal anesthesia. Sixty...
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Effect of Flumazenil on the Anterograde and Retrograde Amnesia Caused by Midazolam

Kim KJ, Kim JY, Lee JJ, Lee KY

We report a case of profound amnesia, anterograde and retrograde, in a patient, who had been premedicated with midazolam and underwent a posterior fusion of the cervical spine under inhalation...
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The Effects of Flumazenil on the Recovery Time and Satisfaction of the Use of Sedative Endoscopy with Midazolam

Kim DK, Jung HY, Ko HM, Jo JY, Kim SG, Lee D, Chang HS, Song HK, Lee HJ, Chung EJ, Park HW, Kim JH

  • KMID: 2084473
  • Korean J Gastrointest Endosc.
  • 2008 Apr;36(4):206-212.
BACKGROUND/AIMS: Treatment with flumazenil results in rapid reversal from sedation. In addition, the use of flumazenil can prevent accidents or memory loss after endoscopy. This study was conducted to evaluate...
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Flumazenil Use in the Emergency Department: Benefit or Risk

Kim HJ, Park KN, Choi SP, Lee MJ, Lee WJ, Kim SK

  • KMID: 2331411
  • J Korean Soc Emerg Med.
  • 2004 Dec;15(6):440-445.
PURPOSE: Flumazenil is frequently administered to poisoned and benzodiazepine-induced sedated patients. However, seizure, resedation, dysrhythmia, and death may occur in patients who awaken following flumazenil administration. Thus, this study investigated...
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Synthesis and Biodistribution of Flumazenil Derivative [F-18](3-(2-Fluoro) flumazenil for Imaging Benzodiazepine Receptor

Hong SH, Jeong JM, Chang YS, Lee DS, Chung JK, Cho JH, Lee SJ, Kang SS, Lee MC

  • KMID: 2038081
  • Korean J Nucl Med.
  • 1999 Dec;33(6):527-536.
PURPOSE: Radiotracers that bind to the central benzodiazepine receptor are useful for the investigation of various neurological and psychiatric diseases. [C-11]Flumazenil, a benzodiazepine antagonist, is the most widely used radioligand...
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Clinical Use of Flumazenil in the Emergency Department for Suspected Benzodiazepine Overdose

Lee MJ, Kim HJ, So BH, Lee WJ, Kim SK

  • KMID: 1998725
  • J Korean Soc Emerg Med.
  • 2003 Dec;14(5):529-535.
PURPOSE: Flumazenil is the specific benzodiazepine (BZP)antagonist indicated for the reversal of the sedative effect of BZP. We evaluated the safety and the effectiveness of using flumazenil to treat suspected...
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Effectiveness of Flumazenil against Midazolam as Premedication for Upper Gastrointestinal Endoscopy

Yun UD, Choi SR, Lee JH, Choi DH, Shin JM, Rho MH, Han SY, Shin WW

  • KMID: 1865459
  • Korean J Gastrointest Endosc.
  • 2000 Jul;21(1):518-524.
BACKGROUND/AIMS: Midazolam is utilized as a premedication for uppoer gastrointestinal endoscopy. Midazolam has a more rapid onset of reaction than that of diazepam and its duration is shorter. But the...
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Effect of flumazenil on recovery from anesthesia and the bispectral index after sevoflurane/fentanyl general anesthesia in unpremedicated patients

Kim YJ, Lee H, Kim CH, Lee GY, Baik HJ, Han JI

BACKGROUND: Benzodiazepines have a hypnotic/sedative effect through the inhibitory action of gamma-aminobutyric acid type A receptor. Flumazenil antagonizes these effects via competitive inhibition, so it has been used to reverse...
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The Effects of Flumazenil and Verapamil on the Relaxation of Midazolam in Isolated Guinea-pig Tracheal Smooth Muscle

Koh SO, Kim KJ, Kim WO, Cho SM, Kim MO

BACKGROUND: Midazolam relaxes airway smooth muscle. The aim of this study is to evaluate the influence of flumazenil or verapamil on the relaxation effects of midazolam in tracheal smooth muscle...
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Delayed Flumazenil Injection after Endoscopic Sedation Increases Patient Satisfaction Compared with Immediate Flumazenil Injection

Chung HJ, Bang BW, Kim HG, Kwon KS, Shin YW, Jeong S, Lee DH, Park SG

  • KMID: 1774522
  • Gut Liver.
  • 2014 Jan;8(1):7-12.
BACKGROUND/AIMS: Flumazenil was administered after the completion of endoscopy under sedation to reduce recovery time and increase patient safety. We evaluated patient satisfaction after endoscopy under sedation according to the...
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Reverse Effect of Flumazenil on the Cerebral and Circulatory Functions Suppressed by Lorazepam in Dogs

Oh YS, Won YC, Kim YL

The effects of lorazepam on cerebral function, metabolism, and hemodynamics were studied in eight dogs receiving a general anesthesia with isoflurane(0.5 vo1%)-50% nitrous oxide-oxy-gen. The effects of benzodiazepine antaronist, flumazenil,...
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Clinical Analysis of Flumazenil Administration in the Single Emergency Department for Unconscious Patients, Suspected Benzodiazepine Overdose

Kim HJ, Kim YH, Lee JH, Hwang SY, Cho KW, Kang MJ, Lee DW, Lee KY, Lee NK

PURPOSE: Flumazenil is an effective benzodiazepine antagonist. However, serious adverse effects, including seizures, cardiac arrhythmias, and even death, have been reported in patients treated with flumazenil. These adverse effects are...
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The Effects of Flumanzenil ( Ro 15-1788 ) at the Conclusion of Anesthesia in the Patients Who Received Midazolam ( Ro 21-3981 ) as an Induction Agent

Chang SH, Chung HK, Lee HW, Lee MK, Lim HJ, Shin JS

The actions and side effcts of the benzodiazepine antagonist flumazenil were evaluated in a clinical study in which midazolam was used as an anesthetir induction agent. Anesthesia was maintained with...
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The Effect of Fixed Dose of Flumazenil on Recovery after Sedative Endoscopy by Midazolam

Kwon KH, Park YS, Kim TH, Jo YJ, Song MH, Kim CH, Kim SH

  • KMID: 1865738
  • Korean J Gastrointest Endosc.
  • 2006 Jun;32(6):361-367.
BACKGROUND/AIMS: Midazolam is widely used as a form of conscious sedation during endoscopy because of its rapid onset and safety. However, its relatively long half-life and paradoxical reactions are still...
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Effects of Midazolam on CNS and Antagonistic Effect of Flumazenil

Choi SJ, Han NH, Kim MH, Son SC, Lee JU

The effects of midazolam and diazepam which were used as an induction agent of general anesthesia were evaluated. And flumazenil which is a potent competitive inhibitor of the specific binding...
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Flumazenil administration in suspected patients with acute hypnotics and sedatives poisoning: risk-benefit re-evaluation

Huh JH, Choi SC, Lim YG, Lampotang , Park EJ

PURPOSE: The use of flumazenil administration in the emergency department is still controversial because of concerns about adverse effects. The present study was conducted to re-evaluate the risk-benefit ratio associated...
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Risperidone in a child with untractable emergency delirium: a case report

Shin YH, Lee SH, Kim DY

A 6-year-old boy was scheduled for thoracic magnetic resonance imaging under deep sedation with midazolam 1.8 mg and propofol 100 µg/kg/min via intravenous injection. He showed emergence delirium in the...
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